STRINGSTRING
AKT2 AKT2 ARRB1 ARRB1 PPP3CA PPP3CA PRKCA PRKCA ENSCSAP00000000542 ENSCSAP00000000542 MAPK10 MAPK10 PPP2R2D PPP2R2D ARNTL ARNTL SLC18A2 SLC18A2 MAPK11 MAPK11 CLOCK CLOCK GNAO1 GNAO1 CREB3L1 CREB3L1 ATF4 ATF4 CACNA1A CACNA1A PRKCB PRKCB CALY CALY GNG3 GNG3 DRD3 DRD3 PLCB3 PLCB3 GSK3B GSK3B PLCB2 PLCB2 PPP2R5B PPP2R5B ADCY5 ADCY5 ITPR2 ITPR2 GNAQ GNAQ MAPK9 MAPK9 KCNJ6 KCNJ6 GRIN2B GRIN2B GRIN2A GRIN2A PPP1CA PPP1CA CREB3L2 CREB3L2 PPP3CB PPP3CB CAMK2G CAMK2G ATF6B ATF6B AKT3 AKT3 DRD1 DRD1 ITPR3 ITPR3 AKT1 AKT1 TH TH CREB1 CREB1 MAPK8 MAPK8 MAPK14 MAPK14 MAPK13 MAPK13 GNB3 GNB3 PPP2R5C PPP2R5C CREB3 CREB3 PPP1CB PPP1CB CREB3L3 CREB3L3 GRIA1 GRIA1 PPP2R3A PPP2R3A ITPR1 ITPR1 CACNA1C CACNA1C GNB5 GNB5 CALM1 CALM1 GNG7 GNG7 PPP2R5D PPP2R5D CAMK2A CAMK2A KIF5B KIF5B GNAI1 GNAI1 COMT COMT FOS FOS GNG10 GNG10 PPP2R2B PPP2R2B GNG11 GNG11 GNB4 GNB4 CACNA1D CACNA1D CALML4 CALML4 PLCB1 PLCB1 PLCB4 PLCB4 PPP2CA PPP2CA PPP2R5E PPP2R5E MAOB MAOB MAOA MAOA GNAI2 GNAI2 CREB5 CREB5 ATF2 ATF2 GNG2 GNG2 PPP2R5A PPP2R5A SCN1A SCN1A PPP2R3C PPP2R3C GNAS GNAS CAMK2B CAMK2B PPP2CB PPP2CB KCNJ3 KCNJ3 DDC DDC PPP2R2A PPP2R2A PPP2R2C PPP2R2C KIF5C KIF5C SLC18A1 SLC18A1 CACNA1B CACNA1B SLC6A3 SLC6A3 GNAL GNAL GNB2 GNB2 GRIA3 GRIA3 PPP2R3B PPP2R3B GSK3A GSK3A GRIA2 GRIA2 GRIA4 GRIA4 GNG8 GNG8 PPP2R1B PPP2R1B DRD2 DRD2 PPP1R1B PPP1R1B PPP1CC PPP1CC KCNJ9 KCNJ9 GNGT2 GNGT2 KCNJ5 KCNJ5 PPP2R1A PPP2R1A PRKCG PRKCG GNAI3 GNAI3 PRKACB PRKACB GNG12 GNG12 GNB1 GNB1 PRKACG PRKACG LOC103243499 LOC103243499 CALML5 CALML5 CALML3 CALML3 DRD5 DRD5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase. (535 aa)
ARRB1Arrestin beta 1. (418 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
ENSCSAP00000000542Uncharacterized protein. (267 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (458 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (583 aa)
SLC18A2Solute carrier family 18 member A2. (517 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
CLOCKClock circadian regulator. (847 aa)
GNAO1G protein subunit alpha o1. (354 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
ATF4Activating transcription factor 4. (351 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1363 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
CALYCalcyon neuron specific vesicular protein. (217 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (403 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GNAQG protein subunit alpha q. (301 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (331 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1402 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1327 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (465 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
THTyrosine hydroxylase. (501 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
GNB3G protein subunit beta 3. (340 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (311 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (811 aa)
PPP2R3AUncharacterized protein. (529 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
GNB5G protein subunit beta 5. (353 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
GNAI1G protein subunit alpha i1. (354 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (270 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNB4G protein subunit beta 4. (340 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
CALML4Calmodulin like 4. (194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (435 aa)
MAOBAmine oxidase. (520 aa)
MAOAAmine oxidase. (527 aa)
GNAI2G protein subunit alpha i2. (355 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
SCN1ASodium voltage-gated channel alpha subunit 1. (1359 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
GNASUncharacterized protein. (335 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
DDCDopa decarboxylase. (480 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2342 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
GNALG protein subunit alpha L. (381 aa)
GNB2G protein subunit beta 2. (340 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
PPP2R3BEF-hand domain-containing protein. (575 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (811 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (599 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (450 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNB1G protein subunit beta 1. (340 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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