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CALHM1 CALHM1 PDE1B PDE1B ADCY6 ADCY6 ASIC2 ASIC2 GABRA5 GABRA5 CACNA1A CACNA1A SCNN1B SCNN1B SCNN1G SCNN1G PLCB3 PLCB3 GABRA3 GABRA3 PLCB2 PLCB2 GABBR1 GABBR1 TRPM5 TRPM5 ITPR3 ITPR3 GRM4 GRM4 ADCY8 ADCY8 GNB3 GNB3 GABRA1 GABRA1 GABRA6 GABRA6 SCNN1A SCNN1A KCNK5 KCNK5 GABBR2 GABBR2 CACNA1C CACNA1C GNAT3 GNAT3 PDE1A PDE1A PLCB1 PLCB1 PLCB4 PLCB4 HCN4 HCN4 PDE1C PDE1C SCN9A SCN9A SCN2A SCN2A SCN3A SCN3A ADCY4 ADCY4 ENTPD2 ENTPD2 GRM1 GRM1 GABRA2 GABRA2 GABRA4 GABRA4 HTR3B HTR3B PRKACB PRKACB TAS1R2 TAS1R2 TAS1R1 TAS1R1 TAS1R3 TAS1R3 HTR1D HTR1D HTR1B HTR1B HTR1E HTR1E P2RY4 P2RY4 PRKACG PRKACG HTR1F HTR1F TAS2R1 TAS2R1 HTR1A HTR1A TAS2R16 TAS2R16 TAS2R3 TAS2R3 TAS2R4 TAS2R4 TAS2R5 TAS2R5 TAS2R38 TAS2R38 TAS2R39 TAS2R39 TAS2R40 TAS2R40 TAS2R60 TAS2R60 TAS2R41 TAS2R41 TAS2R7 TAS2R7 TAS2R8 TAS2R8 TAS2R9 TAS2R9 TAS2R10 TAS2R10 TAS2R13 TAS2R13 TAS2R50 TAS2R50 TAS2R20 TAS2R20 ENSCSAP00000018743 ENSCSAP00000018743 TAS2R19 TAS2R19 TAS2R42 TAS2R42 CHRM3 CHRM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALHM1Calcium homeostasis modulator 1. (346 aa)
PDE1BPhosphodiesterase. (536 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (318 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1363 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (962 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1170 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GRM4Glutamate metabotropic receptor 4. (740 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
GNB3G protein subunit beta 3. (340 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
SCNN1ASodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (669 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
GNAT3G protein subunit alpha transducin 3. (355 aa)
PDE1APhosphodiesterase. (502 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
PDE1CPhosphodiesterase. (520 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1992 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2052 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1701 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (878 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
TAS1R2Taste 1 receptor member 2. (839 aa)
TAS1R1Taste 1 receptor member 1. (841 aa)
TAS1R3Taste 1 receptor member 3. (852 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
HTR1FG_PROTEIN_RECEP_F1_2 domain-containing protein. (366 aa)
TAS2R1Taste receptor type 2. (299 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
TAS2R16Taste receptor type 2. (291 aa)
TAS2R3Taste receptor type 2. (316 aa)
TAS2R4Taste receptor type 2. (299 aa)
TAS2R5Taste receptor type 2. (299 aa)
TAS2R38Taste receptor type 2. (333 aa)
TAS2R39Taste receptor type 2. (338 aa)
TAS2R40Taste receptor type 2. (323 aa)
TAS2R60Taste receptor type 2. (318 aa)
TAS2R41Taste receptor type 2. (307 aa)
TAS2R7Taste receptor type 2. (318 aa)
TAS2R8Taste receptor type 2. (309 aa)
TAS2R9Taste receptor type 2. (311 aa)
TAS2R10Taste 2 receptor member 10. (307 aa)
TAS2R13Taste receptor type 2. (303 aa)
TAS2R50Taste receptor type 2. (299 aa)
TAS2R20Taste receptor type 2. (309 aa)
ENSCSAP00000018743Taste receptor type 2. (309 aa)
TAS2R19Taste receptor type 2. (299 aa)
TAS2R42Taste receptor type 2. (314 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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