STRINGSTRING
PRKCA PRKCA MAPK10 MAPK10 MAP2K6 MAP2K6 MAPK11 MAPK11 ADCY7 ADCY7 PIK3R2 PIK3R2 ASIC1 ASIC1 TRPM8 TRPM8 ADCY6 ADCY6 ASIC2 ASIC2 PRKCB PRKCB HTR2B HTR2B PLA2G6 PLA2G6 PLCB3 PLCB3 PLCB2 PLCB2 ADCY5 ADCY5 MAP2K3 MAP2K3 ITPR2 ITPR2 GNAQ GNAQ PLA2G4B PLA2G4B PLA2G4E PLA2G4E MAPK9 MAPK9 PLA2G4D PLA2G4D PLA2G4F PLA2G4F ADCY3 ADCY3 PPP1CA PPP1CA HTR2C HTR2C TRPV2 TRPV2 CAMK2G CAMK2G KNG1 KNG1 ADCY9 ADCY9 ITPR3 ITPR3 ADCY8 ADCY8 MAPK8 MAPK8 MAPK14 MAPK14 MAPK13 MAPK13 BDKRB2 BDKRB2 PPP1CB PPP1CB ITPR1 ITPR1 PIK3CB PIK3CB CALM1 CALM1 CAMK2A CAMK2A PIK3CA PIK3CA PRKCD PRKCD PLA2G4A PLA2G4A PRKCE PRKCE CALML4 CALML4 PRKCQ PRKCQ PLCB1 PLCB1 TRPA1 TRPA1 PLCB4 PLCB4 TRPV3 TRPV3 SRC SRC PLCG1 PLCG1 PRKCH PRKCH PTGER2 PTGER2 F2RL1 F2RL1 GNAS GNAS CAMK2B CAMK2B ADCY1 ADCY1 ADCY4 ADCY4 PIK3R1 PIK3R1 IL1B IL1B PTGER4 PTGER4 IL1R1 IL1R1 ADCY2 ADCY2 HTR2A HTR2A PLCG2 PLCG2 IGF1 IGF1 ASIC5 ASIC5 TRPV4 TRPV4 PPP1CC PPP1CC NTRK1 NTRK1 PRKCG PRKCG PRKACB PRKACB CYP2J2 CYP2J2 CYP4A22 CYP4A22 PIK3R3 PIK3R3 PIK3CD PIK3CD P2RY2 P2RY2 NGF NGF PRKACG PRKACG LOC103243499 LOC103243499 HRH1 HRH1 CALML5 CALML5 CALML3 CALML3 BDKRB1 BDKRB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
PIK3R2Uncharacterized protein. (629 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (528 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (318 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
PLA2G6Phospholipase A2 group VI. (467 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GNAQG protein subunit alpha q. (301 aa)
PLA2G4BPhospholipase A2. (1012 aa)
PLA2G4EPhospholipase A2. (869 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
PLA2G4DPhospholipase A2. (825 aa)
PLA2G4FPhospholipase A2. (853 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
KNG1Kininogen 1. (427 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PLA2G4APhospholipase A2. (749 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
CALML4Calmodulin like 4. (194 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (745 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (791 aa)
SRCTyrosine-protein kinase. (633 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
GNASUncharacterized protein. (335 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
IGF1Insulin like growth factor 1. (159 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (824 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
CYP4A22Uncharacterized protein. (455 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (241 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
BDKRB1Bradykinin receptor B1. (353 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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