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FSHB FSHB ADCY7 ADCY7 ADCY6 ADCY6 BMP6 BMP6 ADCY5 ADCY5 PLA2G4B PLA2G4B PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F ADCY3 ADCY3 ADCY9 ADCY9 INS INS ADCY8 ADCY8 ALOX5 ALOX5 CYP19A1 CYP19A1 CYP1B1 CYP1B1 ACOT4 ACOT4 ENSCSAP00000008893 ENSCSAP00000008893 BMP15 BMP15 PTGS2 PTGS2 PLA2G4A PLA2G4A LHCGR LHCGR FSHR FSHR ENSCSAP00000009878 ENSCSAP00000009878 AKR1C8P AKR1C8P AKR1C3 AKR1C3 CYP11A1 CYP11A1 CYP1A1 CYP1A1 STAR STAR GNAS GNAS ADCY1 ADCY1 ADCY4 ADCY4 IGF1R IGF1R ADCY2 ADCY2 CGA CGA HSD17B2 HSD17B2 IGF1 IGF1 HSD17B1 HSD17B1 LHB LHB HSD17B7 HSD17B7 SCARB1 SCARB1 HSD3B1 HSD3B1 HSD3B2 HSD3B2 PRKACB PRKACB CYP2J2 CYP2J2 PRKACG PRKACG LOC103243499 LOC103243499
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FSHBFollicle stimulating hormone subunit beta. (129 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
PLA2G4BPhospholipase A2. (1012 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (825 aa)
PLA2G4FPhospholipase A2. (853 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
ACOT4Acyl-CoA thioesterase 4. (421 aa)
ENSCSAP00000008893Uncharacterized protein. (482 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (572 aa)
PLA2G4APhospholipase A2. (749 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (669 aa)
ENSCSAP00000009878Aldo_ket_red domain-containing protein. (324 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (323 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (326 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (464 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
GNASUncharacterized protein. (335 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
IGF1RTyrosine-protein kinase receptor. (1064 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
IGF1Insulin like growth factor 1. (159 aa)
HSD17B1Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
LHBCys_knot domain-containing protein. (141 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (341 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (470 aa)
HSD3B1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (375 aa)
HSD3B2Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2. (447 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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