STRINGSTRING
PPP1R12A PPP1R12A RYR1 RYR1 NFATC3 NFATC3 PPP3CA PPP3CA PRKCA PRKCA CACNG5 CACNG5 CACNG4 CACNG4 CACNG1 CACNG1 GNAO1 GNAO1 MYL6B MYL6B ADCY7 ADCY7 MYLK3 MYLK3 PRKAG1 PRKAG1 MAPK3 MAPK3 CACNB3 CACNB3 ADCY6 ADCY6 PRKAG2 PRKAG2 CACNG3 CACNG3 PRKCB PRKCB NOS3 NOS3 PLCB3 PLCB3 EEF2K EEF2K MYLK4 MYLK4 ROCK2 ROCK2 PLCB2 PLCB2 ADCY5 ADCY5 MYLK MYLK TRPM2 TRPM2 ITPR2 ITPR2 GNAQ GNAQ KRAS KRAS PLA2G4B PLA2G4B CACNG2 CACNG2 MAPK7 MAPK7 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F KCNJ6 KCNJ6 ADCY3 ADCY3 PPP1CA PPP1CA PRKAG3 PRKAG3 PPP3CB PPP3CB CAMK2G CAMK2G CCND1 CCND1 RAF1 RAF1 ADCY9 ADCY9 ITPR3 ITPR3 RYR2 RYR2 MYL9 MYL9 ADCY8 ADCY8 CDKN1A CDKN1A PIK3R5 PIK3R5 PIK3R6 PIK3R6 CAMK1 CAMK1 NPR2 NPR2 PPP1CB PPP1CB MAP2K2 MAP2K2 OXTR OXTR EEF2 EEF2 ITPR1 ITPR1 HRAS HRAS CACNA1C CACNA1C CACNA2D4 CACNA2D4 PIK3CG PIK3CG CALM1 CALM1 CAMK2A CAMK2A GNAI1 GNAI1 CACNA2D1 CACNA2D1 FOS FOS CACNB2 CACNB2 MYLK2 MYLK2 CACNA1F CACNA1F CACNA2D3 CACNA2D3 CACNA1D CACNA1D MAP2K1 MAP2K1 CAMK1D CAMK1D OXT OXT PTGS2 PTGS2 PLA2G4A PLA2G4A RGS2 RGS2 MAP2K5 MAP2K5 CALML4 CALML4 PLCB1 PLCB1 ELK1 ELK1 PLCB4 PLCB4 MAPK1 MAPK1 SRC SRC CACNA1S CACNA1S CACNA2D2 CACNA2D2 GNAI2 GNAI2 PPP3R1 PPP3R1 CAMK4 CAMK4 RHOA RHOA CAMK1G CAMK1G NFATC2 NFATC2 GNAS GNAS CAMK2B CAMK2B ADCY1 ADCY1 NFATC4 NFATC4 ADCY4 ADCY4 KCNJ3 KCNJ3 CACNB4 CACNB4 EGFR EGFR CD38 CD38 PRKAA1 PRKAA1 ADCY2 ADCY2 ROCK1 ROCK1 NFATC1 NFATC1 PRKAB2 PRKAB2 GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 GUCY1A2 GUCY1A2 KCNJ14 KCNJ14 PPP1CC PPP1CC KCNJ9 KCNJ9 PRKAB1 PRKAB1 KCNJ5 KCNJ5 PRKCG PRKCG CACNG7 CACNG7 CACNG8 CACNG8 CACNG6 CACNG6 NPR1 NPR1 PPP1R12C PPP1R12C NRAS NRAS GNAI3 GNAI3 PRKACB PRKACB PRKAA2 PRKAA2 NPPA NPPA KCNJ12 KCNJ12 ENSCSAP00000017469 ENSCSAP00000017469 KCNJ2 KCNJ2 ENSCSAP00000017602 ENSCSAP00000017602 JUN JUN PRKACG PRKACG LOC103243499 LOC103243499 CALML5 CALML5 CALML3 CALML3 KCNJ4 KCNJ4 LOC103247367 LOC103247367
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R12AProtein phosphatase 1 regulatory subunit. (942 aa)
RYR1Ryanodine receptor 1. (4303 aa)
NFATC3RHD domain-containing protein. (637 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (278 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
GNAO1G protein subunit alpha o1. (354 aa)
MYL6BMyosin light chain 6B. (209 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
MYLK3Myosin light chain kinase 3. (874 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (524 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
NOS3Nitric oxide synthase 3. (867 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (443 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
MYLKMyosin light chain kinase. (1914 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GNAQG protein subunit alpha q. (301 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PLA2G4BPhospholipase A2. (1012 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (825 aa)
PLA2G4FPhospholipase A2. (853 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (331 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (464 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
RYR2Ryanodine receptor 2. (4906 aa)
MYL9Myosin light chain 9. (172 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (881 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (749 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
NPR2Guanylate cyclase. (1047 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
EEF2Eukaryotic translation elongation factor 2. (858 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1137 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
GNAI1G protein subunit alpha i1. (354 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (962 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
CACNA1FIon_trans domain-containing protein. (233 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1034 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (288 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (572 aa)
PLA2G4APhospholipase A2. (749 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
CALML4Calmodulin like 4. (194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
ELK1Uncharacterized protein. (296 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SRCTyrosine-protein kinase. (633 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1074 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (614 aa)
RHOARas homolog family member A. (193 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
NFATC2Nuclear factor of activated T cells 2. (928 aa)
GNASUncharacterized protein. (335 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (486 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CD38CD38 molecule. (304 aa)
PRKAA1Non-specific serine/threonine protein kinase. (501 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
NFATC1Nuclear factor of activated T cells 1. (929 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (497 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (436 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (450 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (421 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
NPR1Guanylate cyclase. (1270 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit. (786 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
NPPANatriuretic peptide A. (153 aa)
KCNJ12Uncharacterized protein. (433 aa)
ENSCSAP00000017469Uncharacterized protein. (151 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
ENSCSAP00000017602Uncharacterized protein. (151 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
LOC103247367Uncharacterized protein. (151 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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