STRINGSTRING
ACE ACE PPP3CA PPP3CA PRKG2 PRKG2 PDE3B PDE3B PDE1B PDE1B ADCY6 ADCY6 PLCB3 PLCB3 PLCB2 PLCB2 EDN1 EDN1 ADCY5 ADCY5 ITPR2 ITPR2 GNAQ GNAQ PDE3A PDE3A PPP3CB PPP3CB ITPR3 ITPR3 CREB1 CREB1 AGT AGT ITPR1 ITPR1 CACNA1C CACNA1C AGTR1 AGTR1 CALM1 CALM1 GNAI1 GNAI1 PDE1A PDE1A CACNA1F CACNA1F CACNA1D CACNA1D CALML4 CALML4 PLCB1 PLCB1 PLCB4 PLCB4 CACNA1S CACNA1S ADORA1 ADORA1 GNAI2 GNAI2 REN REN AQP1 AQP1 ADCYAP1R1 ADCYAP1R1 PDE1C PDE1C PPP3R1 PPP3R1 PTGER2 PTGER2 ADRB3 ADRB3 GNAS GNAS EDN3 EDN3 PTGER4 PTGER4 CTSB CTSB EDNRA EDNRA GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 GUCY1A2 GUCY1A2 ORAI1 ORAI1 NPR1 NPR1 GNAI3 GNAI3 ENSCSAP00000016584 ENSCSAP00000016584 CLCA4 CLCA4 CLCA1 CLCA1 CLCA2 CLCA2 PRKACB PRKACB EDN2 EDN2 NPPA NPPA KCNJ2 KCNJ2 ADRB1 ADRB1 PRKACG PRKACG LOC103243499 LOC103243499 CALML5 CALML5 CALML3 CALML3 ADRB2 ADRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACEAngiotensin-converting enzyme. (1040 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
PRKG2cGMP-dependent protein kinase. (675 aa)
PDE3BPhosphodiesterase. (1117 aa)
PDE1BPhosphodiesterase. (536 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
EDN1Endothelin 1. (211 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GNAQG protein subunit alpha q. (301 aa)
PDE3APhosphodiesterase. (1142 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
GNAI1G protein subunit alpha i1. (354 aa)
PDE1APhosphodiesterase. (502 aa)
CACNA1FIon_trans domain-containing protein. (233 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
CALML4Calmodulin like 4. (194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
GNAI2G protein subunit alpha i2. (355 aa)
RENRenin; Belongs to the peptidase A1 family. (406 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (496 aa)
PDE1CPhosphodiesterase. (520 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
GNASUncharacterized protein. (335 aa)
EDN3Endothelin 3. (230 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (497 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (303 aa)
NPR1Guanylate cyclase. (1270 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ENSCSAP00000016584VWFA domain-containing protein. (903 aa)
CLCA4Chloride channel accessory 4. (858 aa)
CLCA1Chloride channel accessory 1. (942 aa)
CLCA2Chloride channel accessory 2. (945 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
EDN2Endothelin 2. (178 aa)
NPPANatriuretic peptide A. (153 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
ADRB1Adrenoceptor beta 1. (482 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ADRB2Adrenoceptor beta 2. (415 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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