STRINGSTRING
AKT2 AKT2 NFKB1 NFKB1 MAPK10 MAPK10 CPT1B CPT1B PPARA PPARA PIK3R2 PIK3R2 OGA OGA CREB3L1 CREB3L1 RPS6KB1 RPS6KB1 PRKAG1 PRKAG1 PRKAG2 PRKAG2 PPP1R3C PPP1R3C PRKCB PRKCB NOS3 NOS3 PTEN PTEN GSK3B GSK3B PYGM PYGM GYS2 GYS2 RELA RELA MAPK9 MAPK9 SREBF1 SREBF1 PPP1CA PPP1CA PRKAG3 PRKAG3 CREB3L2 CREB3L2 CPT1A CPT1A AKT3 AKT3 AKT1 AKT1 INS INS CREB1 CREB1 MAPK8 MAPK8 CREB3 CREB3 RPS6KA6 RPS6KA6 AGT AGT PPP1CB PPP1CB TNFRSF1A TNFRSF1A CREB3L3 CREB3L3 SLC27A2 SLC27A2 PPP1R3A PPP1R3A PIK3CB PIK3CB OGT OGT PPARGC1B PPARGC1B SLC2A4 SLC2A4 CD36 CD36 RPS6KA2 RPS6KA2 SLC2A2 SLC2A2 TRIB3 TRIB3 PIK3CA PIK3CA PRKCD PRKCD PRKCE PRKCE PRKCQ PRKCQ IL6 IL6 SLC27A6 SLC27A6 CREB5 CREB5 RPS6KA3 RPS6KA3 GFPT1 GFPT1 IKBKB IKBKB PYGL PYGL PTPN1 PTPN1 PCK1 PCK1 NFKBIA NFKBIA PIK3R1 PIK3R1 PPP1R3E PPP1R3E PCK2 PCK2 PPARGC1A PPARGC1A PRKAA1 PRKAA1 IRS2 IRS2 TBC1D4 TBC1D4 FOXO1 FOXO1 PDPK1 PDPK1 PRKAB2 PRKAB2 G6PC3 G6PC3 G6PC G6PC STAT3 STAT3 ACACB ACACB GYS1 GYS1 PPP1CC PPP1CC PTPN11 PTPN11 PRKAB1 PRKAB1 NR1H2 NR1H2 MLXIP MLXIP CRTC2 CRTC2 SLC27A3 SLC27A3 SLC27A5 SLC27A5 PRKAA2 PRKAA2 PIK3R3 PIK3R3 PTPRF PTPRF SLC2A1 SLC2A1 RPS6KA1 RPS6KA1 MTOR MTOR PIK3CD PIK3CD PRKCZ PRKCZ PPP1R3B PPP1R3B PPP1R3D PPP1R3D SOCS3 SOCS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase. (535 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
PIK3R2Uncharacterized protein. (629 aa)
OGAO-GlcNAcase. (842 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (524 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
NOS3Nitric oxide synthase 3. (867 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (804 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1123 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (464 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (311 aa)
SLC27A2Solute carrier family 27 member 2. (539 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (910 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
PPARGC1BPPARG coactivator 1 beta. (996 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
RPS6KA2Ribosomal protein S6 kinase. (730 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
TRIB3Tribbles pseudokinase 3. (358 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (745 aa)
IL6Interleukin 6. (212 aa)
SLC27A6Solute carrier family 27 member 6. (619 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
GFPT1Glutamine--fructose-6-phosphate transaminase 1. (681 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (279 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
PRKAA1Non-specific serine/threonine protein kinase. (501 aa)
IRS2Insulin receptor substrate 2. (906 aa)
TBC1D4TBC1 domain family member 4. (1134 aa)
FOXO1Forkhead box O1. (655 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (580 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ACACBAcetyl-CoA carboxylase beta. (2462 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
MLXIPMLX interacting protein. (919 aa)
CRTC2CREB regulated transcription coactivator 2. (603 aa)
SLC27A3Solute carrier family 27 member 3. (731 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1926 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (416 aa)
RPS6KA1Ribosomal protein S6 kinase. (735 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (285 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit. (299 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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