STRINGSTRING
PRKCA PRKCA ATP4A ATP4A ADCY7 ADCY7 MYLK3 MYLK3 ADCY6 ADCY6 PRKCB PRKCB SLC4A2 SLC4A2 PLCB3 PLCB3 MYLK4 MYLK4 PLCB2 PLCB2 ADCY5 ADCY5 MYLK MYLK ITPR2 ITPR2 GNAQ GNAQ ADCY3 ADCY3 CAMK2G CAMK2G SST SST HRH2 HRH2 KCNQ1 KCNQ1 ADCY9 ADCY9 ITPR3 ITPR3 ADCY8 ADCY8 CFTR CFTR ITPR1 ITPR1 ATP1B1 ATP1B1 ATP1B3 ATP1B3 ATP1B2 ATP1B2 CALM1 CALM1 CAMK2A CAMK2A KCNK10 KCNK10 GNAI1 GNAI1 EZR EZR MYLK2 MYLK2 SLC26A7 SLC26A7 CA2 CA2 CALML4 CALML4 PLCB1 PLCB1 PLCB4 PLCB4 GNAI2 GNAI2 KCNK2 KCNK2 GNAS GNAS CAMK2B CAMK2B ADCY1 ADCY1 ADCY4 ADCY4 SLC9A4 SLC9A4 ADCY2 ADCY2 ATP4B ATP4B ATP1B4 ATP1B4 ATP1A3 ATP1A3 GAST GAST ATP1A4 ATP1A4 ATP1A2 ATP1A2 KCNJ1 KCNJ1 PRKCG PRKCG ATP1A1 ATP1A1 GNAI3 GNAI3 PRKACB PRKACB SLC9A1 SLC9A1 SSTR2 SSTR2 KCNJ2 KCNJ2 KCNJ16 KCNJ16 KCNJ10 KCNJ10 PRKACG PRKACG KCNE2 KCNE2 KCNJ15 KCNJ15 LOC103243499 LOC103243499 CALML5 CALML5 CALML3 CALML3 CHRM3 CHRM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1035 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
MYLK3Myosin light chain kinase 3. (874 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
SLC4A2Anion exchange protein. (1237 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (443 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
MYLKMyosin light chain kinase. (1914 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GNAQG protein subunit alpha q. (301 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
SSTSomatostatin. (116 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (518 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
CFTRCFTR_R domain-containing protein. (289 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (265 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (539 aa)
GNAI1G protein subunit alpha i1. (354 aa)
EZREzrin. (584 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
SLC26A7Anion exchange transporter. (656 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
CALML4Calmodulin like 4. (194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
GNAI2G protein subunit alpha i2. (355 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (411 aa)
GNASUncharacterized protein. (335 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (798 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (291 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (356 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1013 aa)
GASTGastrin. (104 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (392 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (418 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (375 aa)
LOC103243499Uncharacterized protein. (251 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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