STRINGSTRING
BCAR1 BCAR1 ELMO3 ELMO3 CDH1 CDH1 RHOG RHOG ILK ILK DOCK1 DOCK1 SEPTIN11 SEPTIN11 SEPTIN9 SEPTIN9 PIK3R2 PIK3R2 ITGA5 ITGA5 SEPTIN3 SEPTIN3 SEPTIN2 SEPTIN2 CLTC CLTC SEPTIN1 SEPTIN1 DNM2 DNM2 HCLS1 HCLS1 SHC3 SHC3 CTNNA3 CTNNA3 ARPC2 ARPC2 VCL VCL CLTB CLTB CTTN CTTN WASL WASL SHC4 SHC4 ARPC4 ARPC4 CAV3 CAV3 MET MET CAV1 CAV1 CAV2 CAV2 PIK3CB PIK3CB ITGB1 ITGB1 CLTCL1 CLTCL1 DNM3 DNM3 ARHGEF26 ARHGEF26 CD2AP CD2AP ARPC5 ARPC5 PIK3CA PIK3CA SHC2 SHC2 CTNNA1 CTNNA1 CRKL CRKL ARPC5L ARPC5L SRC SRC SEPTIN8 SEPTIN8 CRK CRK DNM1 DNM1 ELMO2 ELMO2 ELMO1 ELMO1 RHOA RHOA WASF1 WASF1 CTNNA2-2 CTNNA2-2 PIK3R1 PIK3R1 CTNNB1 CTNNB1 SEPTIN6 SEPTIN6 GAB1 GAB1 ARHGAP10 ARHGAP10 CBL CBL PXN PXN PIK3R3 PIK3R3 WASF2 WASF2 CDC42 CDC42 MAD2L2 MAD2L2 PIK3CD PIK3CD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCAR1BCAR1 scaffold protein, Cas family member. (870 aa)
ELMO3Engulfment and cell motility 3. (720 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
RHOGRas homolog family member G. (191 aa)
ILKIntegrin linked kinase. (452 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1330 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (568 aa)
PIK3R2Uncharacterized protein. (629 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
SEPTIN3Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1495 aa)
SEPTIN1Septin 1. (372 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (497 aa)
SHC3SHC adaptor protein 3. (598 aa)
CTNNA3Uncharacterized protein. (305 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
VCLVinculin. (1134 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
CTTNCortactin. (550 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
SHC4SHC adaptor protein 4. (630 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1381 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1914 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (869 aa)
CD2APCD2 associated protein. (639 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SHC2Uncharacterized protein. (590 aa)
CTNNA1Catenin alpha 1. (906 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
SRCTyrosine-protein kinase. (633 aa)
SEPTIN8Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (483 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (775 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
RHOARas homolog family member A. (193 aa)
WASF1WASP family member 1. (559 aa)
CTNNA2-2Uncharacterized protein. (376 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CTNNB1Catenin beta 1. (781 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (427 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
ARHGAP10Rho GTPase activating protein 10. (797 aa)
CBLCbl proto-oncogene. (907 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (591 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
WASF2WASP family member 2. (498 aa)
CDC42Cell division cycle 42. (191 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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