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PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1055 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (308 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase. (535 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (544 aa) | ||||
FHOD1 | Formin homology 2 domain containing 1. (1149 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (331 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
RHOG | Ras homolog family member G. (191 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (426 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
MLKL | Mixed lineage kinase domain like pseudokinase. (470 aa) | ||||
DYNC1LI2 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa) | ||||
PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1689 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (364 aa) | ||||
EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (720 aa) | ||||
CASP7 | Caspase 7; Belongs to the peptidase C14A family. (303 aa) | ||||
RAB5B | RAB5B, member RAS oncogene family. (215 aa) | ||||
NCKAP1L | NCK associated protein 1 like. (907 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa) | ||||
DYNLL2 | Dynein light chain. (89 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
MYLPF | Myosin light chain, phosphorylatable, fast skeletal muscle. (169 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) | ||||
PKN1 | Protein kinase N1. (944 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (338 aa) | ||||
STX10 | Syntaxin 10; Belongs to the syntaxin family. (249 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa) | ||||
FLNA | Filamin A. (2639 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (686 aa) | ||||
DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa) | ||||
EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (904 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) | ||||
ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa) | ||||
KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) | ||||
CYTH4 | Cytohesin 4. (337 aa) | ||||
VPS18 | VPS18 core subunit of CORVET and HOPS complexes. (973 aa) | ||||
MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
TXN2 | Thioredoxin 2. (166 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) | ||||
KLC2 | Kinesin light chain 2. (483 aa) | ||||
PIK3C2G | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1506 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (517 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (398 aa) | ||||
VPS39 | VPS39 subunit of HOPS complex. (751 aa) | ||||
RAB7A | RAB7A, member RAS oncogene family. (207 aa) | ||||
PAK3 | Non-specific serine/threonine protein kinase. (559 aa) | ||||
ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa) | ||||
NLRP3 | NLR family pyrin domain containing 3. (1035 aa) | ||||
GSDMD | Gasdermin D. (424 aa) | ||||
MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (363 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa) | ||||
FADD | DED domain-containing protein. (189 aa) | ||||
EXOC4 | Exocyst complex component 4. (505 aa) | ||||
M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) | ||||
PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (535 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
RAB5A | RAB5A, member RAS oncogene family. (215 aa) | ||||
FLNC | Filamin C. (2725 aa) | ||||
MYL9 | Myosin light chain 9. (172 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) | ||||
BRK1 | Uncharacterized protein. (75 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (384 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
HSP90AA1 | HATPase_c domain-containing protein. (387 aa) | ||||
WASL | WASP like actin nucleation promoting factor. (505 aa) | ||||
DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4075 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (335 aa) | ||||
ARPC4 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa) | ||||
CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa) | ||||
NLRC4 | NLR family CARD domain containing 4. (1024 aa) | ||||
KLC4 | Kinesin light chain 4. (633 aa) | ||||
ARHGEF26 | Rho guanine nucleotide exchange factor 26. (869 aa) | ||||
ABI1 | Abl interactor 1. (508 aa) | ||||
DYNLRB1 | Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
FLNB | Filamin B. (2602 aa) | ||||
KPNA4 | Importin subunit alpha; Functions in nuclear protein import. (500 aa) | ||||
HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) | ||||
NCKAP1 | NCK associated protein 1. (1128 aa) | ||||
ARPC5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa) | ||||
CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) | ||||
TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) | ||||
DYNLT1 | Dynein light chain Tctex-type 1. (122 aa) | ||||
RIPK2 | Receptor interacting serine/threonine kinase 2. (443 aa) | ||||
DYNC2LI1 | Dynein cytoplasmic 2 light intermediate chain 1. (351 aa) | ||||
PFN1 | Profilin; Belongs to the profilin family. (140 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
DYNC1I1 | Dynein cytoplasmic 1 intermediate chain 1. (628 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) | ||||
SNX9 | Sorting nexin. (618 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) | ||||
LY96 | Lymphocyte antigen 96. (160 aa) | ||||
ARPC5L | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa) | ||||
SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1309 aa) | ||||
LOC103227720 | TIR domain-containing protein. (1032 aa) | ||||
IL6 | Interleukin 6. (212 aa) | ||||
RILP | Rab interacting lysosomal protein. (395 aa) | ||||
RHOJ | Ras homolog family member J. (214 aa) | ||||
TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) | ||||
EXOC5 | Exocyst complex component 5. (708 aa) | ||||
PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa) | ||||
SNX33 | Sorting nexin. (574 aa) | ||||
FBXO22 | F-box protein 22. (438 aa) | ||||
ELMO2 | Engulfment and cell motility 2. (720 aa) | ||||
DYNC1I2 | Dynein cytoplasmic 1 intermediate chain 2. (640 aa) | ||||
RAB7B | RAB7B, member RAS oncogene family. (199 aa) | ||||
CSE1L | Chromosome segregation 1 like. (971 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) | ||||
ELMO1 | Engulfment and cell motility 1. (727 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) | ||||
RALA | RAS like proto-oncogene A. (206 aa) | ||||
MYL5 | Myosin light chain 5. (173 aa) | ||||
NFKBIA | NFKB inhibitor alpha. (317 aa) | ||||
MYL7 | Myosin light chain 7. (175 aa) | ||||
NAIP | NLR family apoptosis inhibitory protein. (1232 aa) | ||||
RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) | ||||
TCF7L1 | Transcription factor 7 like 1. (442 aa) | ||||
TRAF2 | TNF receptor-associated factor. (449 aa) | ||||
FYCO1 | FYVE and coiled-coil domain containing 1. (1478 aa) | ||||
TNFRSF10A | TNF receptor superfamily member 10a. (472 aa) | ||||
ACBD3 | Acyl-CoA binding domain containing 3. (528 aa) | ||||
ARF1 | ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) | ||||
SNX18 | Sorting nexin. (624 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
GCC2 | GRIP and coiled-coil domain containing 2. (1685 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
MYO6 | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa) | ||||
MYL12B | Myosin light chain 12B. (172 aa) | ||||
MYL12A | Myosin light chain 12A. (171 aa) | ||||
KPNA3 | Importin subunit alpha; Functions in nuclear protein import. (504 aa) | ||||
CYTH3 | Cytohesin 3. (399 aa) | ||||
PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) | ||||
WASF3 | WASP family member 3. (502 aa) | ||||
DYNLT3 | Dynein light chain Tctex-type 3. (112 aa) | ||||
MYL10 | Myosin light chain 10. (136 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (239 aa) | ||||
DYNLRB2 | Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa) | ||||
RAB5C | RAB5C, member RAS oncogene family. (255 aa) | ||||
DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4311 aa) | ||||
CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) | ||||
CASP5 | Caspase 5; Belongs to the peptidase C14A family. (325 aa) | ||||
CASP1 | Caspase 1; Belongs to the peptidase C14A family. (462 aa) | ||||
ENSCSAP00000014978 | Uncharacterized protein; Belongs to the peptidase C14A family. (392 aa) | ||||
HSP90B1 | Heat shock protein 90 beta family member 1. (804 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
CYTH2 | Uncharacterized protein. (552 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (192 aa) | ||||
MYL2 | Myosin light chain 2. (166 aa) | ||||
VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) | ||||
RRAS | RAS related. (218 aa) | ||||
CYTH1 | Cytohesin 1. (400 aa) | ||||
TIRAP | TIR domain containing adaptor protein. (220 aa) | ||||
VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (534 aa) | ||||
S100A10 | S_100 domain-containing protein; Belongs to the S-100 family. (199 aa) | ||||
CDC42 | Cell division cycle 42. (191 aa) | ||||
PLEKHM2 | Pleckstrin homology and RUN domain containing M2. (1019 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) | ||||
TLR2 | Toll-like receptor. (784 aa) | ||||
RHOB | Ras homolog family member B. (196 aa) | ||||
RAB9B | RAB9B, member RAS oncogene family. (201 aa) | ||||
TLR5 | Toll like receptor 5; Belongs to the Toll-like receptor family. (858 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) | ||||
TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) | ||||
DYNLL1 | Dynein light chain. (89 aa) | ||||
ENSCSAP00000018835 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) | ||||
ANXA2 | Annexin. (339 aa) | ||||
RAB9A | RAB9A, member RAS oncogene family. (201 aa) | ||||
RHOH | Ras homolog family member H. (191 aa) | ||||
TLR6 | Toll-like receptor. (796 aa) | ||||
PFN3 | Profilin; Belongs to the profilin family. (137 aa) |