STRINGSTRING
AKT2 AKT2 NFKBIB NFKBIB NFKB1 NFKB1 IFNG IFNG MAPK10 MAPK10 MAP2K6 MAP2K6 MAPK11 MAPK11 GNAO1 GNAO1 TRAF6 TRAF6 CHUK CHUK MAPK3 MAPK3 TAB1 TAB1 IKBKG IKBKG IRAK4 IRAK4 IRAK1 IRAK1 BAD BAD NOS2 NOS2 CD40LG CD40LG MAP2K3 MAP2K3 RELA RELA MAPK9 MAPK9 CIITA CIITA JAK2 JAK2 PPIF PPIF AKT3 AKT3 HLA-DRA HLA-DRA HLA-DRB5 HLA-DRB5 HLA-DQA1 HLA-DQA1 HLA-DQB1 HLA-DQB1 HLA-DOB HLA-DOB MHC-DMB MHC-DMB HLA-DMA HLA-DMA HLA-DOA HLA-DOA MHC-DPA1 MHC-DPA1 MHC-DPB1 MHC-DPB1 AKT1 AKT1 IL10RB IL10RB IFNGR2 IFNGR2 MAPK8 MAPK8 MAPK14 MAPK14 MAPK13 MAPK13 PIK3R5 PIK3R5 PIK3R6 PIK3R6 IL12B IL12B TNFRSF1A TNFRSF1A ALOX5 ALOX5 CASP8 CASP8 LAMB4 LAMB4 LAMB1 LAMB1 PIK3CG PIK3CG ITGB1 ITGB1 GNAI1 GNAI1 TGFB3 TGFB3 STAT1 STAT1 IL12A IL12A LAMC1 LAMC1 LAMC2 LAMC2 BCL2L1 BCL2L1 TLR4 TLR4 LY96 LY96 MAPK1 MAPK1 GNAI2 GNAI2 MYD88 MYD88 ITGA6 ITGA6 CD40 CD40 LAMC3 LAMC3 IL10 IL10 IKBKB IKBKB LAMB2 LAMB2 LAMB3 LAMB3 NFKBIA NFKBIA LAMA4 LAMA4 LAMA5 LAMA5 LAMA2 LAMA2 IFNGR1 IFNGR1 TAB2 TAB2 MAP3K7 MAP3K7 LAMA1 LAMA1 LAMA3 LAMA3 BCL2 BCL2 PDPK1 PDPK1 LOC103247136 LOC103247136 ENSCSAP00000014311 ENSCSAP00000014311 ENSCSAP00000014315 ENSCSAP00000014315 XIAP XIAP TGFB1 TGFB1 STAT3 STAT3 CASP3 CASP3 IL10RA IL10RA HSPA8 HSPA8 GNAI3 GNAI3 JAK1 JAK1 TLR2 TLR2 CCR5 CCR5 SOCS1 SOCS1 HSPA1A HSPA1A HSPA1L HSPA1L ENSCSAP00000018835 ENSCSAP00000018835 HSPA2 HSPA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase. (535 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
GNAO1G protein subunit alpha o1. (354 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (338 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (686 aa)
BADBCL2 associated agonist of cell death. (167 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1154 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
CIITAClass II major histocompatibility complex transactivator. (1106 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
HLA-DRB5Ig-like domain-containing protein. (266 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (254 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (261 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (248 aa)
MHC-DMBIg-like domain-containing protein. (263 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (260 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
MHC-DPA1Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
MHC-DPB1Ig-like domain-containing protein. (256 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
IFNGR2Interferon gamma receptor 2. (341 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (881 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (749 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (341 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (496 aa)
LAMB4Laminin subunit beta 4. (1762 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
GNAI1G protein subunit alpha i1. (354 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
LAMC1Laminin subunit gamma 1. (1573 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
BCL2L1BCL2 like 1. (233 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
LY96Lymphocyte antigen 96. (160 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
GNAI2G protein subunit alpha i2. (355 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1073 aa)
CD40CD40 molecule. (278 aa)
LAMC3Uncharacterized protein. (820 aa)
IL10Interleukin 10. (178 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
LAMA5Laminin subunit alpha 5. (3694 aa)
LAMA2Laminin subunit alpha 2. (3147 aa)
IFNGR1Interferon gamma receptor 1. (491 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LAMA1Uncharacterized protein. (1845 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (580 aa)
LOC103247136Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
ENSCSAP00000014311Ig-like domain-containing protein. (252 aa)
ENSCSAP00000014315Ig-like domain-containing protein. (236 aa)
XIAPRING-type domain-containing protein. (497 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
GNAI3G protein subunit alpha i3. (354 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
TLR2Toll-like receptor. (784 aa)
CCR5C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
HSPA1AUncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
ENSCSAP00000018835Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (639 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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