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| | EEA1 | Early endosome antigen 1. (1411 aa) |
| | TRADD | TNFRSF1A associated via death domain. (308 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (535 aa) |
| | MRC2 | Mannose receptor C type 2. (1479 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (471 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | SPHK1 | Sphingosine kinase 1. (472 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | RFXANK | Regulatory factor X associated ankyrin containing protein. (260 aa) |
| | RAB5B | RAB5B, member RAS oncogene family. (215 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1036 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa) |
| | ITGAX | Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1151 aa) |
| | EP300 | E1A binding protein p300. (2416 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | VDR | Vitamin D receptor. (434 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (686 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | SYK | Tyrosine-protein kinase. (635 aa) |
| | NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1154 aa) |
| | ITGB2 | Integrin beta. (784 aa) |
| | KSR1 | Kinase suppressor of ras 1. (851 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (398 aa) |
| | CD209 | CD209 molecule. (360 aa) |
| | CIITA | Class II major histocompatibility complex transactivator. (1106 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (542 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (534 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa) |
| | ENSCSAP00000005199 | Ig-like domain-containing protein. (190 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (588 aa) |
| | ENSCSAP00000005254 | Ig-like domain-containing protein. (191 aa) |
| | ENSCSAP00000005267 | Ig-like domain-containing protein. (146 aa) |
| | ENSCSAP00000005329 | Ig-like domain-containing protein. (126 aa) |
| | ENSCSAP00000005377 | Ig-like domain-containing protein. (139 aa) |
| | ENSCSAP00000005390 | Ig-like domain-containing protein. (189 aa) |
| | LOC103229850 | Ig-like domain-containing protein. (134 aa) |
| | ENSCSAP00000005509 | Ig-like domain-containing protein. (162 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa) |
| | FADD | DED domain-containing protein. (189 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | HLA-DRB5 | Ig-like domain-containing protein. (266 aa) |
| | HLA-DQA1 | Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (254 aa) |
| | HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 1. (261 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (248 aa) |
| | MHC-DMB | Ig-like domain-containing protein. (263 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (260 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | MHC-DPA1 | Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa) |
| | MHC-DPB1 | Ig-like domain-containing protein. (256 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | CREBBP | CREB binding protein. (2417 aa) |
| | IFNA2 | Interferon alpha 2. (190 aa) |
| | CLEC4E | C-type lectin domain family 4 member E. (219 aa) |
| | IFNA8 | Interferon alpha 8. (195 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (325 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (341 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | LSP1 | Lymphocyte specific protein 1. (339 aa) |
| | CTSD | Cathepsin D; Belongs to the peptidase A1 family. (412 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (341 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (520 aa) |
| | HSPD1 | Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (596 aa) |
| | CALM1 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | STAT1 | Signal transducer and activator of transcription. (750 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | MRC1 | Mannose receptor C-type 1. (1456 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | RIPK2 | Receptor interacting serine/threonine kinase 2. (443 aa) |
| | ATP6V0D2 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa) |
| | HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | CALML4 | Calmodulin like 4. (194 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | SRC | Tyrosine-protein kinase. (633 aa) |
| | LBP | Lipopolysaccharide binding protein. (481 aa) |
| | LOC103227720 | TIR domain-containing protein. (1032 aa) |
| | IL6 | Interleukin 6. (212 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa) |
| | PPP3R1 | Protein phosphatase 3 regulatory subunit B, alpha. (170 aa) |
| | IL10 | Interleukin 10. (178 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (628 aa) |
| | PLA2R1 | Phospholipase A2 receptor 1. (1392 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (499 aa) |
| | CAMP | Cathelicidin antimicrobial peptide. (173 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (224 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (491 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (416 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (475 aa) |
| | RFXAP | Regulatory factor X associated protein. (224 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (330 aa) |
| | LOC103247163 | Uncharacterized protein. (357 aa) |
| | MALT1 | MALT1 paracaspase. (729 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | LOC103247136 | Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa) |
| | ENSCSAP00000014311 | Ig-like domain-containing protein. (252 aa) |
| | ENSCSAP00000014315 | Ig-like domain-containing protein. (236 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (837 aa) |
| | RAB5C | RAB5C, member RAS oncogene family. (255 aa) |
| | NFYB | Nuclear transcription factor Y subunit beta. (169 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | SPHK2 | Sphingosine kinase 2. (653 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | LOC103223675 | Uncharacterized protein. (290 aa) |
| | FCGR2A | Uncharacterized protein. (317 aa) |
| | FCER1G | Fc fragment of IgE receptor Ig. (86 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (578 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1544 aa) |
| | TIRAP | TIR domain containing adaptor protein. (220 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa) |
| | RFX5 | Regulatory factor X5. (621 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | ENSCSAP00000017563 | Uncharacterized protein. (189 aa) |
| | ENSCSAP00000017564 | Uncharacterized protein. (189 aa) |
| | IFNA6 | Interferon alpha 6. (189 aa) |
| | IFNA14 | Interferon alpha 14. (189 aa) |
| | ENSCSAP00000017567 | Uncharacterized protein. (189 aa) |
| | ENSCSAP00000017568 | Uncharacterized protein. (189 aa) |
| | ENSCSAP00000017569 | Uncharacterized protein. (189 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (344 aa) |
| | CALML5 | Calmodulin like 5. (146 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | LOC103221492 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | ENSCSAP00000018835 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCSAP00000019090 | Ig-like domain-containing protein. (103 aa) |
| | TLR6 | Toll-like receptor. (796 aa) |
| | TLR1 | Toll like receptor 1; Belongs to the Toll-like receptor family. (786 aa) |
