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| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | MAD2L1 | HORMA domain-containing protein. (75 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (535 aa) |
| | CDC27 | Cell division cycle 27. (824 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | NFATC3 | RHD domain-containing protein. (637 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (471 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | VAC14 | VAC14 component of PIKFYVE complex. (782 aa) |
| | BUB3 | BUB3 mitotic checkpoint protein. (293 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | CRTC1 | CREB regulated transcription coactivator 1. (619 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa) |
| | PIK3R2 | Uncharacterized protein. (629 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (899 aa) |
| | JAK3 | Tyrosine-protein kinase. (1069 aa) |
| | ESPL1 | Extra spindle pole bodies like 1, separase. (1729 aa) |
| | TSPO | Translocator protein. (193 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (146 aa) |
| | EP300 | E1A binding protein p300. (2416 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | CALR | Calreticulin. (417 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | BUB1B | BUB1 N-terminal domain-containing protein. (1051 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (532 aa) |
| | EGR2 | Early growth response 2. (476 aa) |
| | ITGB2 | Integrin beta. (784 aa) |
| | IL2RB | Interleukin 2 receptor subunit beta. (551 aa) |
| | ADCY5 | Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa) |
| | E2F3 | E2F_CC-MB domain-containing protein. (224 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | ENSCSAP00000004095 | Ig-like domain-containing protein. (166 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (522 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) |
| | HLA-F | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (348 aa) |
| | Chsa-A | MHC class IA antigen; Belongs to the MHC class I family. (365 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (398 aa) |
| | CANX | Calnexin. (610 aa) |
| | Chsa-B | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | ETS2 | ETS proto-oncogene 2, transcription factor. (391 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | DLG1 | Uncharacterized protein; Belongs to the MAGUK family. (800 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (534 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (255 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (363 aa) |
| | ATF6B | Activating transcription factor 6 beta. (711 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | HLA-DRB5 | Ig-like domain-containing protein. (266 aa) |
| | HLA-DQA1 | Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (254 aa) |
| | HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 1. (261 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (248 aa) |
| | MHC-DMB | Ig-like domain-containing protein. (263 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (260 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | MHC-DPA1 | Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa) |
| | MHC-DPB1 | Ig-like domain-containing protein. (256 aa) |
| | MSX2 | Msh homeobox 2. (267 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | CREBBP | CREB binding protein. (2417 aa) |
| | ENSCSAP00000005944 | Uncharacterized protein. (173 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (137 aa) |
| | RANBP3 | RAN binding protein 3. (499 aa) |
| | KAT2B | Lysine acetyltransferase 2B. (675 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | CD4 | CD4 molecule. (560 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | TLN1 | Talin 1. (2558 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | LTBR | Lymphotoxin beta receptor. (435 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (311 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | TSPO2 | Translocator protein 2. (170 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | SRF | Serum response factor. (508 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | TBP | TATA-box binding protein. (270 aa) |
| | TCF3 | Transcription factor 3. (581 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) |
| | RANBP1 | RanBD1 domain-containing protein. (201 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | TLN2 | Talin 2. (2542 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | IL2RA | Interleukin 2 receptor subunit alpha. (274 aa) |
| | ELK1 | Uncharacterized protein. (296 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | ENSCSAP00000010032 | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (361 aa) |
| | IL6 | Interleukin 6. (212 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | XPO1 | Exportin 1. (1071 aa) |
| | ELK4 | ETS transcription factor ELK4. (431 aa) |
| | CD40 | CD40 molecule. (278 aa) |
| | PPP3R1 | Protein phosphatase 3 regulatory subunit B, alpha. (170 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (928 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | ADCY1 | Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (901 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1345 aa) |
| | MSX1 | Msh homeobox 1. (303 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (786 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | CRTC3 | CREB regulated transcription coactivator 3. (620 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (418 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3848 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | SLC25A6 | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (929 aa) |
| | LOC103247136 | Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa) |
| | LOC103247147 | Ig-like domain-containing protein; Belongs to the MHC class I family. (362 aa) |
| | ENSCSAP00000014311 | Ig-like domain-containing protein. (252 aa) |
| | ENSCSAP00000014315 | Ig-like domain-containing protein. (236 aa) |
| | XIAP | RING-type domain-containing protein. (497 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (440 aa) |
| | MMP7 | Matrix metallopeptidase 7. (270 aa) |
| | STAT5A | Signal transducer and activator of transcription. (798 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | NFYB | Nuclear transcription factor Y subunit beta. (169 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (346 aa) |
| | CD3E | CD3e molecule. (197 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | CD3G | CD3g molecule. (209 aa) |
| | CHEK1 | Checkpoint kinase 1. (749 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (441 aa) |
| | ANAPC11 | RING-type domain-containing protein. (84 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (742 aa) |
| | FDPS | Uncharacterized protein. (192 aa) |
| | RAN | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (152 aa) |
| | CRTC2 | CREB regulated transcription coactivator 2. (603 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | CDC20 | Cell division cycle 20. (499 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (416 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa) |
| | ENSCSAP00000018428 | Uncharacterized protein. (202 aa) |
