STRINGSTRING
fliW fliW csrA csrA ADL42225.1 ADL42225.1 ADL42235.1 ADL42235.1 ADL42236.1 ADL42236.1 ADL42237.1 ADL42237.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fliWProtein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (152 aa)
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (80 aa)
ADL42225.1Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (274 aa)
ADL42235.1PFAM: flagellar protein FlaG protein; KEGG: csc:Csac_1698 flagellar protein FlaG protein. (131 aa)
ADL42236.1Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (523 aa)
ADL42237.1KEGG: ate:Athe_1652 flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS. (125 aa)
Your Current Organism:
Caldicellulosiruptor obsidiansis
NCBI taxonomy Id: 608506
Other names: C. obsidiansis OB47, Caldicellulosiruptor obsidiansis OB47, Caldicellulosiruptor obsidiansis str. OB47, Caldicellulosiruptor obsidiansis strain OB47, Caldicellulosiruptor sp. OB47
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