(39 nodes) Ribosomal large subunit biogenesis, and Nucleolar complex-associated protein network (Harpegnathos saltator)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EAI_03263	Ribosomal L1 domain-containing protein 1. (412 aa)
	EAI_15525	Putative RNA methyltransferase NOL1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (778 aa)
	EAI_14179	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (607 aa)
	EAI_14186	Ribosomal L1 domain-containing protein 1. (413 aa)
	EAI_00399	WD repeat-containing protein 74. (414 aa)
	EAI_00122	Uncharacterized protein. (58 aa)
	EAI_11947	Probable ribosome production factor 1. (145 aa)
	EAI_15607	Notchless protein-like protein 1. (420 aa)
	EAI_07866	Protein MAK16-like protein A. (325 aa)
	EAI_17504	Guanine nucleotide-binding protein-like 3-like protein. (557 aa)
	EAI_11586	Zinc finger protein 593-like protein. (142 aa)
	EAI_16030	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (426 aa)
	EAI_12396	mRNA turnover protein 4-like protein. (143 aa)
	EAI_16687	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (765 aa)
	EAI_06927	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (439 aa)
	EAI_02935	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (829 aa)
	EAI_09978	Ribosomal RNA processing protein 1-like protein. (517 aa)
	EAI_00498	Brix domain-containing protein 2-like protein. (93 aa)
	EAI_15428	MKI67 FHA domain-interacting nucleolar phosphoprotein-like. (244 aa)
	EAI_00621	Brix domain-containing protein 1-like protein. (179 aa)
	EAI_00622	Brix domain-containing protein 1. (315 aa)
	EAI_01902	Nucleolar complex protein 3-like protein. (1055 aa)
	EAI_01904	Nucleolar complex protein 3-like protein. (662 aa)
	EAI_01523	Ribosome biogenesis protein NSA2-like protein. (259 aa)
	EAI_01585	Nucleolar complex protein 2-like protein. (600 aa)
	EAI_09283	Probable rRNA-processing protein EBP2-like protein. (310 aa)
	EAI_12308	Probable ATP-dependent RNA helicase pitchoune; Belongs to the DEAD box helicase family. (327 aa)
	EAI_12309	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (312 aa)
	EAI_16615	Nucleolar complex protein 2-like protein. (554 aa)
	EAI_14157	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (416 aa)
	EAI_16263	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (641 aa)
	EAI_11010	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	EAI_11053	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (853 aa)
	EAI_01279	Pumilio domain-containing protein KIAA0020-like protein. (664 aa)
	EAI_09804	Putative methyltransferase NSUN6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (442 aa)
	EAI_12206	RNA helicase. (431 aa)
	EAI_11329	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (742 aa)
	EAI_14513	RNA helicase. (588 aa)
	EAI_06737	Probable ribosome biogenesis protein RLP24. (172 aa)

Your Current Organism:

Harpegnathos saltator

NCBI taxonomy Id: 610380
Other names: H. saltator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAI_00122	EAI_00399	E2BBI7	E2BA52	Uncharacterized protein.	WD repeat-containing protein 74.	0.933
EAI_00122	EAI_00498	E2BBI7	E2BJM3	Uncharacterized protein.	Brix domain-containing protein 2-like protein.	0.815
EAI_00122	EAI_00621	E2BBI7	E2BMJ2	Uncharacterized protein.	Brix domain-containing protein 1-like protein.	0.803
EAI_00122	EAI_00622	E2BBI7	E2BMJ3	Uncharacterized protein.	Brix domain-containing protein 1.	0.803
EAI_00122	EAI_01279	E2BBI7	E2BXL1	Uncharacterized protein.	Pumilio domain-containing protein KIAA0020-like protein.	0.844
EAI_00122	EAI_01523	E2BBI7	E2BPH7	Uncharacterized protein.	Ribosome biogenesis protein NSA2-like protein.	0.927
EAI_00122	EAI_01585	E2BBI7	E2BPN6	Uncharacterized protein.	Nucleolar complex protein 2-like protein.	0.768
EAI_00122	EAI_01902	E2BBI7	E2BNG6	Uncharacterized protein.	Nucleolar complex protein 3-like protein.	0.776
EAI_00122	EAI_01904	E2BBI7	E2BNG8	Uncharacterized protein.	Nucleolar complex protein 3-like protein.	0.776
EAI_00122	EAI_02935	E2BBI7	E2BI62	Uncharacterized protein.	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.	0.967
EAI_00122	EAI_03263	E2BBI7	E2B6F5	Uncharacterized protein.	Ribosomal L1 domain-containing protein 1.	0.854
EAI_00122	EAI_06737	E2BBI7	E2C6A3	Uncharacterized protein.	Probable ribosome biogenesis protein RLP24.	0.878
EAI_00122	EAI_06927	E2BBI7	E2BHL7	Uncharacterized protein.	Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.	0.884
EAI_00122	EAI_07866	E2BBI7	E2BE98	Uncharacterized protein.	Protein MAK16-like protein A.	0.912
EAI_00122	EAI_09283	E2BBI7	E2BPV6	Uncharacterized protein.	Probable rRNA-processing protein EBP2-like protein.	0.911
EAI_00122	EAI_09804	E2BBI7	E2BY39	Uncharacterized protein.	Putative methyltransferase NSUN6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.852
EAI_00122	EAI_09978	E2BBI7	E2BJ40	Uncharacterized protein.	Ribosomal RNA processing protein 1-like protein.	0.770
EAI_00122	EAI_11010	E2BBI7	E2BWU0	Uncharacterized protein.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.931
EAI_00122	EAI_11053	E2BBI7	E2BWY3	Uncharacterized protein.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.937
EAI_00122	EAI_11329	E2BBI7	E2C013	Uncharacterized protein.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.900