STRINGSTRING
MAP2K2 MAP2K2 ZFR2 ZFR2 MAPK10 MAPK10 MATK MATK NFKBIE NFKBIE NFKB1 NFKB1 MAP3K1 MAP3K1 FRS2 FRS2 RAF1 RAF1 CALM2 CALM2 CAMK2B CAMK2B AKT1 AKT1 RAP1B RAP1B NTF3 NTF3 IRAK3 IRAK3 CSK CSK IKBKB IKBKB IRAK2 IRAK2 MAPK9 MAPK9 RPS6KA5 RPS6KA5 CALM1 CALM1 MAP2K1 MAP2K1 SOS1 SOS1 MAP2K7 MAP2K7 ZFR ZFR NTRK3 NTRK3 MAP2K5 MAP2K5 MAPK11 MAPK11 MAPK12 MAPK12 CALML5 CALML5 CALML4 CALML4 ENSLCNP00005006752 ENSLCNP00005006752 PRKCD PRKCD PLCG1 PLCG1 GRB2 GRB2 CAMK2G CAMK2G NGFR NGFR RAPGEF1 RAPGEF1 BEX3 BEX3 ABL1 ABL1 PDPK1 PDPK1 CALM3 CALM3 MAP3K3 MAP3K3 RPS6KA6 RPS6KA6 AKT3 AKT3 ENSLCNP00005032262 ENSLCNP00005032262 TP73 TP73 NGF NGF NFKBIB NFKBIB ERAS ERAS NTRK1 NTRK1 BDNF BDNF CSDE1 CSDE1 NTF4 NTF4 NRAS NRAS MAPK3 MAPK3 BAX BAX SHC1 SHC1 PSEN2 PSEN2 ENSLCNP00005028782 ENSLCNP00005028782 FASLG FASLG CALML6 CALML6 ARHGDIA ARHGDIA MAPKAPK2 MAPKAPK2 ENSLCNP00005027979 ENSLCNP00005027979 SH2B1 SH2B1 RPS6KA3 RPS6KA3 RAP1A RAP1A AKT2 AKT2 SH2B2 SH2B2 MAPK8 MAPK8 ENSLCNP00005026019 ENSLCNP00005026019 MAGED1 MAGED1 PVALEF PVALEF PIK3CB PIK3CB RIPK2 RIPK2 PLCG2 PLCG2 KRAS KRAS MAPK7 MAPK7 GSK3B GSK3B HRAS HRAS MAPK1 MAPK1 ARHGDIG ARHGDIG BRAF BRAF SORT1 SORT1 NTRK2 NTRK2 CRK CRK YWHAE YWHAE RELA RELA ZNF274 ZNF274 CDC42 CDC42 ZSCAN1 ZSCAN1 CEP152 CEP152 TRAF6 TRAF6 SHC4 SHC4 SHC3 SHC3 FOXO3 FOXO3 TP53 TP53 MAP3K5 MAP3K5 SH2B3 SH2B3 BAD BAD PPP1R14B PPP1R14B PIK3CA PIK3CA CRKL CRKL PTPN11 PTPN11 CAMK2D CAMK2D RPS6KA1 RPS6KA1 PIK3R1 PIK3R1 BCL2 BCL2 LOC115519995 LOC115519995 IRS1 IRS1 ARHGDIB ARHGDIB PIK3CD PIK3CD RHOA RHOA PRDM4 PRDM4 IRAK4 IRAK4 KIDINS220 KIDINS220 GAB1 GAB1 SOS2 SOS2 ATF4 ATF4 NFKBIA NFKBIA ENSLCNP00005009418 ENSLCNP00005009418 JUN JUN ENSLCNP00005009304 ENSLCNP00005009304 CAMK2A CAMK2A ARSI ARSI ENSLCNP00005009211 ENSLCNP00005009211 PIK3R2 PIK3R2 CAMK4 CAMK4 MAPK13 MAPK13 MAPK14 MAPK14 CALML3 CALML3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K2Mitogen-activated protein kinase kinase 2. (426 aa)
ZFR2Zinc finger RNA binding protein 2. (768 aa)
MAPK10Mitogen-activated protein kinase 10. (465 aa)
MATKMegakaryocyte-associated tyrosine kinase. (466 aa)
NFKBIENFKB inhibitor epsilon. (362 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1509 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
CALM2Calmodulin 2. (154 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (448 aa)
AKT1AKT serine/threonine kinase 1. (754 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
NTF3Neurotrophin 3. (277 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (611 aa)
CSKC-terminal Src kinase. (450 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (783 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (618 aa)
MAPK9Mitogen-activated protein kinase 9. (424 aa)
RPS6KA5Ribosomal protein S6 kinase A5. (798 aa)
CALM1Calmodulin 3. (150 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (458 aa)
ZFRZinc finger RNA binding protein. (1073 aa)
NTRK3Neurotrophic receptor tyrosine kinase 3. (863 aa)
MAP2K5Mitogen-activated protein kinase kinase 5. (448 aa)
MAPK11Mitogen-activated protein kinase 11. (445 aa)
MAPK12Mitogen-activated protein kinase 12. (367 aa)
CALML5Calmodulin-like. (149 aa)
CALML4Calmodulin like 4. (196 aa)
ENSLCNP00005006752annotation not available (582 aa)
PRKCDProtein kinase C delta. (672 aa)
PLCG1Phospholipase C gamma 1. (1290 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (567 aa)
NGFRNerve growth factor receptor. (430 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1232 aa)
BEX3Brain expressed X-linked 3. (118 aa)
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase. (1150 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
CALM3Calmodulin 3. (149 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (635 aa)
RPS6KA6Ribosomal protein S6 kinase A6. (744 aa)
AKT3AKT serine/threonine kinase 3. (479 aa)
ENSLCNP00005032262annotation not available (385 aa)
TP73Tumor protein p73. (632 aa)
NGFNerve growth factor. (294 aa)
NFKBIBNFKB inhibitor beta. (354 aa)
ERASES cell expressed Ras. (233 aa)
NTRK1Neurotrophic receptor tyrosine kinase 1. (785 aa)
BDNFBrain derived neurotrophic factor. (255 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NTF4Neurotrophin 4. (210 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MAPK3Mitogen-activated protein kinase 3. (379 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
SHC1SHC adaptor protein 1. (584 aa)
PSEN2Presenilin 2. (559 aa)
ENSLCNP00005028782annotation not available (85 aa)
FASLGFas ligand. (280 aa)
CALML6Calmodulin like 6. (232 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (204 aa)
MAPKAPK2MAPK activated protein kinase 2. (402 aa)
ENSLCNP00005027979annotation not available (191 aa)
SH2B1SH2B adaptor protein 1. (760 aa)
RPS6KA3Ribosomal protein S6 kinase A3. (740 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
AKT2AKT serine/threonine kinase 2. (481 aa)
SH2B2SH2B adaptor protein 2. (676 aa)
MAPK8Mitogen-activated protein kinase 8. (384 aa)
ENSLCNP00005026019annotation not available (570 aa)
MAGED1MAGE family member D1. (781 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta. (1070 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (538 aa)
PLCG2Phospholipase C gamma 2. (1265 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK7Mitogen-activated protein kinase 7. (804 aa)
GSK3BGlycogen synthase kinase 3 beta. (433 aa)
HRASHRas proto-oncogene, GTPase. (195 aa)
MAPK1Mitogen-activated protein kinase 1. (360 aa)
ARHGDIGRho GDP dissociation inhibitor gamma. (223 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
SORT1Sortilin 1. (877 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (827 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon. (255 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
ZNF274Zinc finger protein 274. (622 aa)
CDC42Cell division cycle 42. (191 aa)
ZSCAN1Zinc finger and SCAN domain containing 1. (423 aa)
CEP152Centrosomal protein 152. (1712 aa)
TRAF6TNF receptor associated factor 6. (541 aa)
SHC4SHC adaptor protein 4. (630 aa)
SHC3SHC adaptor protein 3. (587 aa)
FOXO3Forkhead box O3. (672 aa)
TP53Tumor protein p53. (415 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
SH2B3SH2B adaptor protein 3. (578 aa)
BADBCL2 associated agonist of cell death. (168 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (147 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. (1068 aa)
CRKLCRK like proto-oncogene, adaptor protein. (344 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (597 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
RPS6KA1Ribosomal protein S6 kinase A1. (744 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
BCL2BCL2 apoptosis regulator. (231 aa)
LOC115519995Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
IRS1Insulin receptor substrate 1. (1236 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta. (1044 aa)
RHOARas homolog family member A. (193 aa)
PRDM4PR/SET domain 4. (801 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
KIDINS220Kinase D interacting substrate 220. (1783 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ATF4Activating transcription factor 4. (351 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
ENSLCNP00005009418annotation not available (85 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit. (334 aa)
ENSLCNP00005009304annotation not available (191 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (479 aa)
ARSIArylsulfatase family member I. (575 aa)
ENSLCNP00005009211annotation not available (133 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (640 aa)
MAPK13Mitogen-activated protein kinase 13. (366 aa)
MAPK14Mitogen-activated protein kinase 14. (360 aa)
CALML3Calmodulin-like protein 3. (149 aa)
Your Current Organism:
Lynx canadensis
NCBI taxonomy Id: 61383
Other names: Canada lynx, Felis canadensis, L. canadensis
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