(46 nodes) Glycine, serine and threonine metabolism network (Linderina pennispora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1Y1WK50	Uncharacterized protein. (482 aa)
	A0A1Y1WAH3	Tryptophan synthase beta subunit-like PLP-dependent enzyme. (505 aa)
	A0A1Y1W9U4	Phosphoserine phosphatase serb. (660 aa)
	A0A1Y1W9T1	NAD(P)-binding protein. (363 aa)
	A0A1Y1W9D3	2-amino-3-ketobutyrate coenzyme A ligase. (391 aa)
	A0A1Y1W934	Phosphoglycerate mutase-like protein. (267 aa)
	A0A1Y1W8F6	Creatinase/aminopeptidase; Belongs to the peptidase M24B family. (613 aa)
	A0A1Y1W8D6	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (509 aa)
	A0A1Y1WAJ6	Arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12. (353 aa)
	A0A1Y1WB01	Phosphoserine phosphatase serb. (677 aa)
	A0A1Y1WBP1	Aromatic amino acid beta-eliminating lyase/threonine aldolase. (334 aa)
	A0A1Y1WBP3	Beta_elim_lyase domain-containing protein. (377 aa)
	A0A1Y1WCZ6	L-serine ammonia-lyase. (505 aa)
	A0A1Y1WG40	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (463 aa)
	A0A1Y1WH21	Aspartate-semialdehyde dehydrogenase. (360 aa)
	A0A1Y1WHJ7	DAO-domain-containing protein. (500 aa)
	A0A1Y1WHM9	Nucleotide-binding domain-containing protein. (317 aa)
	A0A1Y1WHV0	FAD dependent oxidoreductase. (328 aa)
	A0A1Y1WIR2	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (508 aa)
	A0A1Y1WIR9	Aminotran_5 domain-containing protein. (417 aa)
	A0A1Y1WJ60	Dihydrolipoyl dehydrogenase. (490 aa)
	A0A1Y1WJ71	Tryptophan synthase beta subunit-like PLP-dependent enzyme. (435 aa)
	A0A1Y1WKJ5	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (603 aa)
	A0A1Y1WKU7	AMP_N domain-containing protein. (539 aa)
	A0A1Y1WM64	Threonine dehydratase. (566 aa)
	A0A1Y1WM78	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (416 aa)
	A0A1Y1WMD1	Ribosomal protein L1. (235 aa)
	A0A1Y1WMS9	3-phosphoserine/phosphohydroxythreonine aminotransferase. (388 aa)
	A0A1Y1WN19	P-loop containing nucleoside triphosphate hydrolase protein. (307 aa)
	A0A1Y1VQ19	Uncharacterized protein. (91 aa)
	A0A1Y1VS57	Short-chain dehydrogenase/reductase SDR. (226 aa)
	A0A1Y1VYV8	Putative Xaa-Pro aminopeptidase P; Belongs to the peptidase M24B family. (642 aa)
	A0A1Y1VZQ4	NAD(P)-binding protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
	A0A1Y1WNU5	Aspartokinase. (550 aa)
	A0A1Y1W844	Uncharacterized protein. (126 aa)
	A0A1Y1W7Q6	Phosphoglycerate mutase-like protein. (224 aa)
	A0A1Y1W7H7	Phosphoglycerate mutase-like protein. (197 aa)
	A0A1Y1W7E3	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (500 aa)
	A0A1Y1W5K7	AMP_N domain-containing protein. (402 aa)
	A0A1Y1W5H6	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (130 aa)
	A0A1Y1W427	Homoserine kinase. (351 aa)
	A0A1Y1W3U4	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1026 aa)
	A0A1Y1W2A4	2,3-bisphosphoglycerate-independent phosphoglycerate mutase. (511 aa)
	A0A1Y1W0U9	Tryptophan synthase. (701 aa)
	A0A1Y1W0U0	Uncharacterized protein. (354 aa)
	A0A1Y1W0G6	Homoserine dehydrogenase. (353 aa)

Your Current Organism:

Linderina pennispora

NCBI taxonomy Id: 61395
Other names: ATCC 12442, CBS 312.51, L. pennispora, NRRL 2237

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y1VQ19	A0A1Y1W0G6	Uncharacterized protein.	Homoserine dehydrogenase.	0.523
A0A1Y1VQ19	A0A1Y1W0U0	Uncharacterized protein.	Uncharacterized protein.	0.441
A0A1Y1VQ19	A0A1Y1W0U9	Uncharacterized protein.	Tryptophan synthase.	0.730
A0A1Y1VQ19	A0A1Y1W427	Uncharacterized protein.	Homoserine kinase.	0.485
A0A1Y1VQ19	A0A1Y1W5H6	Uncharacterized protein.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.474
A0A1Y1VQ19	A0A1Y1W7E3	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.600
A0A1Y1VQ19	A0A1Y1W7H7	Uncharacterized protein.	Phosphoglycerate mutase-like protein.	0.494
A0A1Y1VQ19	A0A1Y1W7Q6	Uncharacterized protein.	Phosphoglycerate mutase-like protein.	0.494
A0A1Y1VQ19	A0A1Y1W934	Uncharacterized protein.	Phosphoglycerate mutase-like protein.	0.494
A0A1Y1VQ19	A0A1Y1W9U4	Uncharacterized protein.	Phosphoserine phosphatase serb.	0.795
A0A1Y1VQ19	A0A1Y1WAH3	Uncharacterized protein.	Tryptophan synthase beta subunit-like PLP-dependent enzyme.	0.858
A0A1Y1VQ19	A0A1Y1WB01	Uncharacterized protein.	Phosphoserine phosphatase serb.	0.795
A0A1Y1VQ19	A0A1Y1WG40	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.600
A0A1Y1VQ19	A0A1Y1WH21	Uncharacterized protein.	Aspartate-semialdehyde dehydrogenase.	0.583
A0A1Y1VQ19	A0A1Y1WHJ7	Uncharacterized protein.	DAO-domain-containing protein.	0.415
A0A1Y1VQ19	A0A1Y1WIR2	Uncharacterized protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.730
A0A1Y1VQ19	A0A1Y1WIR9	Uncharacterized protein.	Aminotran_5 domain-containing protein.	0.796
A0A1Y1VQ19	A0A1Y1WM78	Uncharacterized protein.	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.974
A0A1Y1VQ19	A0A1Y1WNU5	Uncharacterized protein.	Aspartokinase.	0.466
A0A1Y1VS57	A0A1Y1W0U0	Short-chain dehydrogenase/reductase SDR.	Uncharacterized protein.	0.521