45 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CTSG	Cathepsin G; Belongs to the peptidase S1 family. (255 aa)
	GCA	Grancalcin. (218 aa)
	ENSRBIP00000000419	Uncharacterized protein. (191 aa)
	CD164	CD164 molecule. (163 aa)
	MMP9	Matrix metallopeptidase 9. (703 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	S100A8	EF-hand domain-containing protein; Belongs to the S-100 family. (171 aa)
	SELPLG	Selectin P ligand. (408 aa)
	CXCR4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	LOC108544547	Uncharacterized protein. (399 aa)
	S100A12	S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa)
	ITGB2	Integrin beta. (779 aa)
	SMAP2	Small ArfGAP2. (429 aa)
	ENSRBIP00000015347	Uncharacterized protein. (182 aa)
	ENSRBIP00000016224	Uncharacterized protein. (184 aa)
	PRTN3	Proteinase 3; Belongs to the peptidase S1 family. (258 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
	CD8A	CD8a molecule. (235 aa)
	SNAP23	Synaptosome associated protein 23. (211 aa)
	PEAK3	PEAK family member 3. (455 aa)
	TNFSF13B	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (317 aa)
	AZU1	Azurocidin 1. (250 aa)
	MMP8	Matrix metallopeptidase 8. (465 aa)
	VNN2	Vanin 2. (492 aa)
	ELANE	Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
	ENSRBIP00000026615	Uncharacterized protein. (185 aa)
	LAT2	Linker for activation of T cells family member 2. (242 aa)
	CD4	CD4 molecule. (458 aa)
	MPO	Myeloperoxidase. (719 aa)
	LCN2	Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (200 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (159 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	TAPBP	TAP binding protein. (504 aa)
	CRP	Pentaxin. (224 aa)
	KIAA1109	KIAA1109. (5003 aa)
	ITGAM	Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
	CDC42	Uncharacterized protein. (191 aa)
	ENSRBIP00000037737	annotation not available (191 aa)
	TNFRSF1A	TNF receptor superfamily member 1A. (455 aa)
	PLBD1	Phospholipase B-like; Putative phospholipase. (553 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	IL10	Interleukin 10. (178 aa)
	IL6	Interleukin 6. (214 aa)
	TREM1	Triggering receptor expressed on myeloid cells 1. (248 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AZU1	CTSG	ENSRBIP00000022546	ENSRBIP00000026644	Azurocidin 1.	Cathepsin G; Belongs to the peptidase S1 family.	0.825
AZU1	ELANE	ENSRBIP00000022546	ENSRBIP00000025795	Azurocidin 1.	Elastase, neutrophil expressed; Belongs to the peptidase S1 family.	0.952
AZU1	MPO	ENSRBIP00000022546	ENSRBIP00000031207	Azurocidin 1.	Myeloperoxidase.	0.968
AZU1	PRTN3	ENSRBIP00000022546	ENSRBIP00000017258	Azurocidin 1.	Proteinase 3; Belongs to the peptidase S1 family.	0.948
CD164	CXCR4	ENSRBIP00000003793	ENSRBIP00000011022	CD164 molecule.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.452
CD4	CD8A	ENSRBIP00000030374	ENSRBIP00000018190	CD4 molecule.	CD8a molecule.	0.972
CD4	CRP	ENSRBIP00000030374	ENSRBIP00000033981	CD4 molecule.	Pentaxin.	0.608
CD4	CTSG	ENSRBIP00000030374	ENSRBIP00000026644	CD4 molecule.	Cathepsin G; Belongs to the peptidase S1 family.	0.496
CD4	CXCR4	ENSRBIP00000030374	ENSRBIP00000011022	CD4 molecule.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.857
CD4	IFNG	ENSRBIP00000030374	ENSRBIP00000031792	CD4 molecule.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.713
CD4	IL10	ENSRBIP00000030374	ENSRBIP00000041136	CD4 molecule.	Interleukin 10.	0.882
CD4	IL1B	ENSRBIP00000030374	ENSRBIP00000017788	CD4 molecule.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.757
CD4	IL6	ENSRBIP00000030374	ENSRBIP00000041408	CD4 molecule.	Interleukin 6.	0.737
CD4	ITGAM	ENSRBIP00000030374	ENSRBIP00000035398	CD4 molecule.	Integrin subunit alpha M; Belongs to the integrin alpha chain family.	0.464
CD4	ITGB2	ENSRBIP00000030374	ENSRBIP00000014350	CD4 molecule.	Integrin beta.	0.655
CD4	LCN2	ENSRBIP00000030374	ENSRBIP00000031474	CD4 molecule.	Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family.	0.571
CD4	MMP9	ENSRBIP00000030374	ENSRBIP00000004926	CD4 molecule.	Matrix metallopeptidase 9.	0.708
CD4	MPO	ENSRBIP00000030374	ENSRBIP00000031207	CD4 molecule.	Myeloperoxidase.	0.555
CD4	TNF	ENSRBIP00000030374	ENSRBIP00000011080	CD4 molecule.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.700
CD4	TREM1	ENSRBIP00000030374	ENSRBIP00000042660	CD4 molecule.	Triggering receptor expressed on myeloid cells 1.	0.453