STRINGSTRING
NDRG1 NDRG1 TGM2 TGM2 VEGFC VEGFC OCLN OCLN ARL4A ARL4A ECSCR ECSCR FN1 FN1 TNFAIP2 TNFAIP2 ZNF71 ZNF71 ENSRBIP00000001766 ENSRBIP00000001766 CCN2 CCN2 EMCN EMCN EPHB4 EPHB4 ZRANB1 ZRANB1 KDR KDR S1PR1 S1PR1 TNFRSF25 TNFRSF25 PLTP PLTP MED6 MED6 AKAP12 AKAP12 RIPK2 RIPK2 SNN SNN DOCK5 DOCK5 RPL5 RPL5 ABI1 ABI1 TXNDC17 TXNDC17 RORA RORA PTX3 PTX3 ACE ACE ZNF580 ZNF580 CHST2 CHST2 ENSRBIP00000007227 ENSRBIP00000007227 CDCA8 CDCA8 GNS GNS NDST1 NDST1 VCL VCL STAB2 STAB2 FLNB FLNB VEGFD VEGFD ADAMTS1 ADAMTS1 CFLAR CFLAR AKT1 AKT1 CLDN5 CLDN5 ENSRBIP00000010821 ENSRBIP00000010821 PPP3CC PPP3CC NR2F2 NR2F2 FIBP FIBP ICAM2 ICAM2 RASD2 RASD2 ENSRBIP00000012433 ENSRBIP00000012433 JAG1 JAG1 LIPG LIPG BMPR2 BMPR2 CLEC4G CLEC4G SCD5 SCD5 IDS IDS ESM1 ESM1 ENSRBIP00000016866 ENSRBIP00000016866 LYVE1 LYVE1 POLI POLI PLXDC1 PLXDC1 ENSRBIP00000018120 ENSRBIP00000018120 ERN1 ERN1 VCAM1 VCAM1 JAM2 JAM2 TMEM204 TMEM204 GP1BA GP1BA STYX STYX P4HA3 P4HA3 HHIP HHIP ENSRBIP00000020717 ENSRBIP00000020717 ITGA10 ITGA10 ENSRBIP00000022247 ENSRBIP00000022247 FOSL1 FOSL1 MYLK MYLK PTGS2 PTGS2 TNFAIP1 TNFAIP1 NDOR1 NDOR1 LOC108535228 LOC108535228 FAM124B FAM124B EIF3M EIF3M ECE2 ECE2 FGD6 FGD6 TBXA2R TBXA2R HERPUD1 HERPUD1 TJP1 TJP1 EFNB2 EFNB2 ENSRBIP00000025670 ENSRBIP00000025670 FADD FADD KCNIP2 KCNIP2 CDC5L CDC5L LOC108524591 LOC108524591 FOSL2 FOSL2 KIF20A KIF20A PDSS1 PDSS1 VWF VWF SMAD7 SMAD7 ZFP2 ZFP2 LOC108529197 LOC108529197 LOC108524163 LOC108524163 PECAM1 PECAM1 IRAK2 IRAK2 ENSRBIP00000029534 ENSRBIP00000029534 PROCR PROCR GATA2 GATA2 LAMC1 LAMC1 ENSRBIP00000030563 ENSRBIP00000030563 SKIL SKIL ADD2 ADD2 POGLUT2 POGLUT2 ENSRBIP00000031955 ENSRBIP00000031955 ICAM1 ICAM1 NOD1 NOD1 SELE SELE RANBP1 RANBP1 DGKE DGKE PROX1 PROX1 NOS3 NOS3 CDH5 CDH5 CSGALNACT2 CSGALNACT2 CHST1 CHST1 ITGA2 ITGA2 VEGFA VEGFA ANXA2 ANXA2 ENSRBIP00000035705 ENSRBIP00000035705 IL33 IL33 FLT4 FLT4 OTOGL OTOGL ARNTL2 ARNTL2 ECE1 ECE1 ARL1 ARL1 SCARF1 SCARF1 CD109 CD109 ENSRBIP00000040145 ENSRBIP00000040145 ANGPT2 ANGPT2 PDE4D PDE4D THBS1 THBS1 DGKZ DGKZ ATRIP ATRIP RIPK1 RIPK1 ENSRBIP00000043665 ENSRBIP00000043665
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NDRG1N-myc downstream regulated 1. (394 aa)
TGM2Transglutaminase 2. (687 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (350 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
ARL4AADP ribosylation factor like GTPase 4A. (200 aa)
ECSCRUncharacterized protein. (205 aa)
FN1Fibronectin 1. (2477 aa)
TNFAIP2TNF alpha induced protein 2. (593 aa)
ZNF71Zinc finger protein 71. (432 aa)
ENSRBIP00000001766Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (379 aa)
CCN2Cellular communication network factor 2. (387 aa)
EMCNEndomucin. (266 aa)
EPHB4EPH receptor B4. (987 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (726 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
TNFRSF25TNF receptor superfamily member 25. (419 aa)
PLTPPhospholipid transfer protein. (493 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (257 aa)
AKAP12A-kinase anchoring protein 12. (1783 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
SNNStannin. (88 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1834 aa)
RPL5Ribosomal protein L5. (298 aa)
ABI1Abl interactor 1. (508 aa)
TXNDC17Thioredoxin domain containing 17. (123 aa)
RORARAR related orphan receptor A. (555 aa)
PTX3Pentraxin 3. (381 aa)
ACEAngiotensin-converting enzyme. (1307 aa)
ZNF580Zinc finger protein 580. (172 aa)
CHST2Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa)
ENSRBIP00000007227Ribosomal_L18_c domain-containing protein. (266 aa)
CDCA8Cell division cycle associated 8. (280 aa)
GNSGlucosamine (N-acetyl)-6-sulfatase. (584 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (883 aa)
VCLVinculin. (1118 aa)
STAB2Stabilin 2. (2560 aa)
FLNBFilamin B. (2633 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (480 aa)
AKT1AKT serine/threonine kinase 1. (486 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
ENSRBIP00000010821Uncharacterized protein. (441 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
NR2F2NR LBD domain-containing protein. (264 aa)
FIBPFGF1 intracellular binding protein. (357 aa)
ICAM2Intercellular adhesion molecule 2. (319 aa)
RASD2RASD family member 2. (266 aa)
ENSRBIP00000012433Uncharacterized protein. (53 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
LIPGLipase G, endothelial type. (500 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CLEC4GC-type lectin domain family 4 member G. (293 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa)
IDSSulfatase domain-containing protein. (550 aa)
ESM1Endothelial cell specific molecule 1. (184 aa)
ENSRBIP00000016866Uncharacterized protein. (101 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa)
POLIDNA polymerase iota. (738 aa)
PLXDC1Plexin domain containing 1. (500 aa)
ENSRBIP00000018120RanBD1 domain-containing protein. (187 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (980 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
JAM2Junctional adhesion molecule 2. (309 aa)
TMEM204Transmembrane protein 204. (145 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (599 aa)
STYXSerine/threonine/tyrosine interacting protein. (223 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha 3. (544 aa)
HHIPHedgehog interacting protein. (700 aa)
ENSRBIP00000020717Uncharacterized protein. (428 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
MYLKMyosin light chain kinase. (1656 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
TNFAIP1TNF alpha induced protein 1. (316 aa)
NDOR1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (597 aa)
LOC108535228Uncharacterized protein. (115 aa)
FAM124BFamily with sequence similarity 124 member B. (455 aa)
EIF3MEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (368 aa)
ECE2EEF1AKMT4-ECE2 readthrough. (883 aa)
FGD6FYVE, RhoGEF and PH domain containing 6. (1431 aa)
TBXA2RThromboxane A2 receptor. (379 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1737 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (312 aa)
ENSRBIP00000025670Uncharacterized protein. (68 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (252 aa)
CDC5LCell division cycle 5 like. (786 aa)
LOC108524591Uncharacterized protein. (73 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
PDSS1Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (369 aa)
VWFVon Willebrand factor. (2813 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
ZFP2ZFP2 zinc finger protein. (488 aa)
LOC108529197Tr-type G domain-containing protein. (478 aa)
LOC108524163Uncharacterized protein. (383 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (756 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (537 aa)
ENSRBIP00000029534Tr-type G domain-containing protein. (433 aa)
PROCRProtein C receptor. (238 aa)
GATA2GATA binding protein 2. (468 aa)
LAMC1Laminin subunit gamma 1. (1587 aa)
ENSRBIP00000030563Uncharacterized protein. (332 aa)
SKILSKI like proto-oncogene. (692 aa)
ADD2Adducin 2. (738 aa)
POGLUT2Protein O-glucosyltransferase 2. (521 aa)
ENSRBIP00000031955Uncharacterized protein. (75 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
SELESelectin E. (610 aa)
RANBP1RAN binding protein 1. (278 aa)
DGKEDiacylglycerol kinase. (566 aa)
PROX1Prospero homeobox 1. (737 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
CSGALNACT2Hexosyltransferase. (538 aa)
CHST1Sulfotransferase; Belongs to the sulfotransferase 1 family. (432 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa)
ANXA2Annexin. (357 aa)
ENSRBIP00000035705Uncharacterized protein. (200 aa)
IL33Interleukin 33. (269 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1329 aa)
OTOGLOtogelin like. (2237 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator like 2. (672 aa)
ECE1Endothelin converting enzyme 1. (872 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
SCARF1Scavenger receptor class F member 1. (782 aa)
CD109CD109 molecule. (1404 aa)
ENSRBIP00000040145Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (205 aa)
ANGPT2Angiopoietin 2. (510 aa)
PDE4DPhosphodiesterase. (809 aa)
THBS1Thrombospondin 1. (1170 aa)
DGKZDiacylglycerol kinase. (1102 aa)
ATRIPATR interacting protein. (790 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (672 aa)
ENSRBIP00000043665Tr-type G domain-containing protein. (457 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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