6 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IGF1	Insulin like growth factor 1. (208 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	INSRR	Tyrosine-protein kinase receptor. (1301 aa)
	INSR	Tyrosine-protein kinase receptor. (1372 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1335 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1	IGF1R	ENSRBIP00000008759	ENSRBIP00000041773	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.998
IGF1	IGF2	ENSRBIP00000008759	ENSRBIP00000038768	Insulin like growth factor 1.	Insulin like growth factor 2.	0.973
IGF1	INS	ENSRBIP00000008759	ENSRBIP00000015729	Insulin like growth factor 1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.961
IGF1	INSR	ENSRBIP00000008759	ENSRBIP00000024320	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.975
IGF1	INSRR	ENSRBIP00000008759	ENSRBIP00000021458	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.932
IGF1R	IGF1	ENSRBIP00000041773	ENSRBIP00000008759	Tyrosine-protein kinase receptor.	Insulin like growth factor 1.	0.998
IGF1R	IGF2	ENSRBIP00000041773	ENSRBIP00000038768	Tyrosine-protein kinase receptor.	Insulin like growth factor 2.	0.997
IGF1R	INS	ENSRBIP00000041773	ENSRBIP00000015729	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.994
IGF1R	INSR	ENSRBIP00000041773	ENSRBIP00000024320	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.899
IGF1R	INSRR	ENSRBIP00000041773	ENSRBIP00000021458	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.682
IGF2	IGF1	ENSRBIP00000038768	ENSRBIP00000008759	Insulin like growth factor 2.	Insulin like growth factor 1.	0.973
IGF2	IGF1R	ENSRBIP00000038768	ENSRBIP00000041773	Insulin like growth factor 2.	Tyrosine-protein kinase receptor.	0.997
IGF2	INS	ENSRBIP00000038768	ENSRBIP00000015729	Insulin like growth factor 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.567
IGF2	INSR	ENSRBIP00000038768	ENSRBIP00000024320	Insulin like growth factor 2.	Tyrosine-protein kinase receptor.	0.898
IGF2	INSRR	ENSRBIP00000038768	ENSRBIP00000021458	Insulin like growth factor 2.	Tyrosine-protein kinase receptor.	0.816
INS	IGF1	ENSRBIP00000015729	ENSRBIP00000008759	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin like growth factor 1.	0.961
INS	IGF1R	ENSRBIP00000015729	ENSRBIP00000041773	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.994
INS	IGF2	ENSRBIP00000015729	ENSRBIP00000038768	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin like growth factor 2.	0.567
INS	INSR	ENSRBIP00000015729	ENSRBIP00000024320	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.985
INS	INSRR	ENSRBIP00000015729	ENSRBIP00000021458	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.985