STRINGSTRING
PAK5 PAK5 LOC108543755 LOC108543755 IQGAP1 IQGAP1 RHOH RHOH LOC108515883 LOC108515883 ELMO1 ELMO1 PAK6 PAK6 DOCK9 DOCK9 ARHGEF6 ARHGEF6 PAK4 PAK4 LOC108543756 LOC108543756 RHOB RHOB FMNL1 FMNL1 PLEKHG4B PLEKHG4B ARHGEF25 ARHGEF25 DOCK11 DOCK11 RAC1 RAC1 RHOU RHOU GNA13 GNA13 ROCK1 ROCK1 RHOJ RHOJ INKA1 INKA1 ARHGEF16 ARHGEF16 ARHGAP1 ARHGAP1 NCK1 NCK1 ENSRBIP00000013802 ENSRBIP00000013802 DOCK2 DOCK2 DOCK3 DOCK3 ENSRBIP00000015347 ENSRBIP00000015347 ENSRBIP00000016224 ENSRBIP00000016224 LOC108522676 LOC108522676 ELMO3 ELMO3 GNA12 GNA12 ARHGEF33 ARHGEF33 IQGAP2 IQGAP2 PAK1 PAK1 GMIP GMIP PAK2 PAK2 MYO9A MYO9A MYO9B MYO9B ST6GALNAC6 ST6GALNAC6 IQGAP3 IQGAP3 ARHGEF7 ARHGEF7 ARHGEF11 ARHGEF11 ARHGEF12 ARHGEF12 ENSRBIP00000025260 ENSRBIP00000025260 GIT1 GIT1 FMNL2 FMNL2 ENSRBIP00000026615 ENSRBIP00000026615 ARHGEF1 ARHGEF1 RTKN RTKN TRIO TRIO BNIP2 BNIP2 AKAP13 AKAP13 GNG12 GNG12 ENSRBIP00000031600 ENSRBIP00000031600 DOCK4 DOCK4 ARHGEF18 ARHGEF18 RHOC RHOC ARHGAP8 ARHGAP8 NCK2 NCK2 ARHGEF28 ARHGEF28 ELMO2 ELMO2 CDC42 CDC42 RHOV RHOV ENSRBIP00000037737 ENSRBIP00000037737 RHOF RHOF RAC2 RAC2 DOCK1 DOCK1 ADRA1A ADRA1A DOCK10 DOCK10 ABR ABR ROCK2 ROCK2 ARHGEF10 ARHGEF10 GIT2 GIT2 KALRN KALRN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAK5Non-specific serine/threonine protein kinase. (719 aa)
LOC108543755Uncharacterized protein. (191 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1630 aa)
RHOHRas homolog family member H. (191 aa)
LOC108515883Uncharacterized protein. (198 aa)
ELMO1Engulfment and cell motility 1. (692 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
DOCK9Dedicator of cytokinesis 9; Belongs to the DOCK family. (2116 aa)
ARHGEF6DH domain-containing protein. (402 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
LOC108543756Uncharacterized protein. (191 aa)
RHOBRas homolog family member B. (196 aa)
FMNL1Formin like 1. (1086 aa)
PLEKHG4BPleckstrin homology and RhoGEF domain containing G4B. (1579 aa)
ARHGEF25Uncharacterized protein. (606 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (1794 aa)
RAC1Uncharacterized protein. (209 aa)
RHOURas homolog family member U. (231 aa)
GNA13G protein subunit alpha 13. (353 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
RHOJRas homolog family member J. (214 aa)
INKA1Inka box actin regulator 1. (287 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (709 aa)
ARHGAP1Rho GTPase activating protein 1. (523 aa)
NCK1NCK adaptor protein 1. (371 aa)
ENSRBIP00000013802Uncharacterized protein. (354 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1880 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2008 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
LOC108522676Protein kinase domain-containing protein. (299 aa)
ELMO3Engulfment and cell motility 3. (768 aa)
GNA12G protein subunit alpha 12. (322 aa)
ARHGEF33Rho guanine nucleotide exchange factor 33. (853 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
GMIPGEM interacting protein. (974 aa)
PAK2Non-specific serine/threonine protein kinase. (539 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2533 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2161 aa)
ST6GALNAC6ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (374 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1663 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (755 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1561 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1536 aa)
ENSRBIP00000025260PH domain-containing protein. (137 aa)
GIT1GIT ArfGAP 1. (817 aa)
FMNL2Formin like 2. (1027 aa)
ENSRBIP00000026615Uncharacterized protein. (185 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (968 aa)
RTKNRhotekin. (563 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3073 aa)
BNIP2BCL2 interacting protein 2. (404 aa)
AKAP13A-kinase anchoring protein 13. (2816 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSRBIP00000031600Uncharacterized protein. (180 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1957 aa)
ARHGEF18Uncharacterized protein. (1173 aa)
RHOCRas homolog family member C. (193 aa)
ARHGAP8Uncharacterized protein. (464 aa)
NCK2Cytoplasmic protein. (380 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1685 aa)
ELMO2Engulfment and cell motility 2. (718 aa)
CDC42Uncharacterized protein. (191 aa)
RHOVRas homolog family member V. (236 aa)
ENSRBIP00000037737annotation not available (191 aa)
RHOFRas homolog family member F, filopodia associated. (211 aa)
RAC2Rac family small GTPase 2. (192 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1930 aa)
ADRA1AAdrenoceptor alpha 1A. (455 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2155 aa)
ABRABR activator of RhoGEF and GTPase. (859 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1361 aa)
GIT2GIT ArfGAP 2. (762 aa)
KALRNKalirin RhoGEF kinase. (2940 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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