STRINGSTRING
REL REL TNIP2 TNIP2 NOD2 NOD2 BIRC3 BIRC3 RIPK2 RIPK2 IKBKE IKBKE MAP3K7 MAP3K7 TAB1 TAB1 IRAK3 IRAK3 ENSRBIP00000006958 ENSRBIP00000006958 NFKB2 NFKB2 TRAF5 TRAF5 MYD88 MYD88 TRAF1 TRAF1 TNF TNF BIRC2 BIRC2 NFKB1 NFKB1 PELI3 PELI3 TAB2 TAB2 NFKBIE NFKBIE IKBKG IKBKG MAP3K20 MAP3K20 RELA RELA TRAF4 TRAF4 TRADD TRADD NFKBIB NFKBIB ENSRBIP00000022247 ENSRBIP00000022247 PELI1 PELI1 CHUK CHUK MAP3K14 MAP3K14 TANK TANK IRAK1 IRAK1 IKBKB IKBKB MAP3K8 MAP3K8 IRAK2 IRAK2 TRAF2 TRAF2 RELB RELB NOD1 NOD1 ENSRBIP00000033406 ENSRBIP00000033406 TRAF6 TRAF6 PELI2 PELI2 TAB3 TAB3 ENSRBIP00000038500 ENSRBIP00000038500 IRAK4 IRAK4 TNFRSF1A TNFRSF1A NFKBIA NFKBIA TRAF3 TRAF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RELREL proto-oncogene, NF-kB subunit. (602 aa)
TNIP2CCHC NOA-type domain-containing protein. (337 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
ENSRBIP00000006958TNF receptor-associated factor. (473 aa)
NFKB2Nuclear factor kappa B subunit 2. (906 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (563 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
TRAF1TNF receptor-associated factor. (416 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (397 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
NFKBIENFKB inhibitor epsilon. (479 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
RELAUncharacterized protein. (282 aa)
TRAF4TNF receptor-associated factor. (463 aa)
TRADDTNFRSF1A associated via death domain. (248 aa)
NFKBIBNFKB inhibitor beta. (338 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
TANKTRAF family member associated NFKB activator. (425 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (702 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (466 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (537 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
RELBRELB proto-oncogene, NF-kB subunit. (541 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
ENSRBIP00000033406UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (690 aa)
ENSRBIP00000038500RHD domain-containing protein. (112 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (461 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
TRAF3TNF receptor-associated factor. (477 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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