STRINGSTRING
WNT4 WNT4 TCF7L2 TCF7L2 WNT6 WNT6 DKK3 DKK3 SFRP4 SFRP4 WNT3 WNT3 SFRP2 SFRP2 DKK2 DKK2 CTNNBIP1 CTNNBIP1 PRICKLE2 PRICKLE2 FZD9 FZD9 FZD5 FZD5 UCK2 UCK2 KREMEN2 KREMEN2 KREMEN1 KREMEN1 FZD10 FZD10 RYK RYK GSK3A GSK3A WNT2B WNT2B LEF1 LEF1 DVL3 DVL3 ROR1 ROR1 TCF7 TCF7 DACT1 DACT1 VANGL2 VANGL2 CER1 CER1 CSNK1A1L CSNK1A1L TCF7L1 TCF7L1 FZD7 FZD7 NLK NLK PRICKLE3 PRICKLE3 WIF1 WIF1 DAAM1 DAAM1 NOTUM NOTUM WNT10B WNT10B LOC108525319 LOC108525319 DVL2 DVL2 CELSR1 CELSR1 TERT TERT SFRP1 SFRP1 CSNK1A1 CSNK1A1 APC APC NMRK1 NMRK1 WLS WLS SFRP5 SFRP5 BAMBI BAMBI DVL1 DVL1 PRICKLE4 PRICKLE4 LRP6 LRP6 CTNNB1 CTNNB1 WNT8B WNT8B DKK4 DKK4 LOC108539219 LOC108539219 APC2 APC2 DKK1 DKK1 GSK3B GSK3B WNT16 WNT16 PORCN PORCN WNT9A WNT9A WNT5B WNT5B WNT8A WNT8A WNT9B WNT9B FZD4 FZD4 AMER1 AMER1 AXIN2 AXIN2 ENSRBIP00000030934 ENSRBIP00000030934 ATCAY ATCAY WNT3A WNT3A FZD3 FZD3 SOX17 SOX17 VANGL1 VANGL1 WNT1 WNT1 WNT7B WNT7B ANKRD6 ANKRD6 AXIN1 AXIN1 PRICKLE1 PRICKLE1 KIAA1549 KIAA1549 FRAT1 FRAT1 WNT11 WNT11 WNT7A WNT7A WNT5A WNT5A WNT2 WNT2 INVS INVS LRP5L LRP5L FZD6 FZD6 WNT10A WNT10A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
TCF7L2HMG box domain-containing protein. (376 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (350 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
PRICKLE2Prickle planar cell polarity protein 2. (900 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
UCK2Uridine-cytidine kinase 2. (228 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (486 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
RYKReceptor like tyrosine kinase. (526 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (444 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
LEF1Lymphoid enhancer binding factor 1. (398 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (936 aa)
TCF7Transcription factor 7. (399 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
VANGL2Vang-like protein. (547 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
CSNK1A1LCasein kinase 1 alpha 1 like. (243 aa)
TCF7L1Transcription factor 7 like 1. (440 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
PRICKLE3Prickle planar cell polarity protein 3. (605 aa)
WIF1WNT inhibitory factor 1. (333 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1073 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (319 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC108525319Protein kinase domain-containing protein. (236 aa)
DVL2Dishevelled segment polarity protein 2. (735 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2716 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1167 aa)
SFRP1Secreted frizzled related protein 1. (313 aa)
CSNK1A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (344 aa)
APCAPC regulator of WNT signaling pathway. (2768 aa)
NMRK1Nicotinamide riboside kinase 1. (143 aa)
WLSWnt ligand secretion mediator. (543 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
DVL1DIX domain-containing protein. (356 aa)
PRICKLE4Uncharacterized protein. (385 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
LOC108539219Protein kinase domain-containing protein. (224 aa)
APC2APC regulator of WNT signaling pathway 2. (2255 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (467 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
AMER1APC membrane recruitment protein 1. (805 aa)
AXIN2Axin 2. (843 aa)
ENSRBIP00000030934Protein kinase domain-containing protein. (188 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (343 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SOX17SRY-box transcription factor 17. (412 aa)
VANGL1Vang-like protein. (524 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ANKRD6Ankyrin repeat domain 6. (727 aa)
AXIN1Axin 1. (867 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
KIAA1549KIAA1549. (1915 aa)
FRAT1FRAT regulator of WNT signaling pathway 1. (257 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
INVSInversin. (1066 aa)
LRP5LLDL receptor related protein 5 like. (251 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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