STRINGSTRING
GPR119 GPR119 HTR1A HTR1A RGS12 RGS12 RGS8 RGS8 CRH CRH TAS2R5 TAS2R5 TAS1R2 TAS1R2 CHRM3 CHRM3 FBXO46 FBXO46 LPAR5 LPAR5 HRH1 HRH1 HTR1D HTR1D RGS4 RGS4 PREX1 PREX1 RGS9BP RGS9BP HTR7 HTR7 DRD3 DRD3 GNA11 GNA11 ADCY6 ADCY6 PTH PTH ADORA1 ADORA1 RGS13 RGS13 VIPR1 VIPR1 PTHLH PTHLH P2RY1 P2RY1 GNB4 GNB4 CASR CASR RAMP1 RAMP1 PLCB1 PLCB1 IAPP IAPP ENSRBIP00000007423 ENSRBIP00000007423 CHRM1 CHRM1 CRHR2 CRHR2 TMIGD3 TMIGD3 GNAZ GNAZ PTGER4 PTGER4 GNA14 GNA14 LPAR2 LPAR2 RGS16 RGS16 GNG7 GNG7 GNG13 GNG13 ENSRBIP00000010613 ENSRBIP00000010613 GRK6 GRK6 LTB4R2 LTB4R2 CHRM5 CHRM5 GNAT3 GNAT3 LPAR3 LPAR3 ENSRBIP00000011770 ENSRBIP00000011770 LPAR6 LPAR6 GPRC6A GPRC6A LRP10 LRP10 ENSRBIP00000013012 ENSRBIP00000013012 RGS14 RGS14 LPAR4 LPAR4 HTR1B HTR1B HTR6 HTR6 LOC108520845 LOC108520845 PTH2 PTH2 GNAI1 GNAI1 RIC8A RIC8A LOC108523537 LOC108523537 GRM5 GRM5 SLC6A4 SLC6A4 PTRHD1 PTRHD1 GPR158 GPR158 GNAO1 GNAO1 RGS9 RGS9 GNB2 GNB2 GCGR GCGR PLCZ1 PLCZ1 PTH1R PTH1R SCT SCT ADM2 ADM2 GNB3 GNB3 PTH2R PTH2R ADRB1 ADRB1 RGS2 RGS2 GNG4 GNG4 GNG5 GNG5 RAMP3 RAMP3 ADCYAP1 ADCYAP1 GNG11 GNG11 GRK5 GRK5 LOC108522831 LOC108522831 GHRHR GHRHR SCTR SCTR ADCY9 ADCY9 RGS18 RGS18 ADCY3 ADCY3 PDC PDC GNG2 GNG2 ENSRBIP00000022449 ENSRBIP00000022449 PTGER3 PTGER3 PLCB3 PLCB3 RGS17 RGS17 GLP2R GLP2R ADCY2 ADCY2 ADORA2A ADORA2A ENSRBIP00000024798 ENSRBIP00000024798 TBXA2R TBXA2R GNA15 GNA15 RGS1 RGS1 F2R F2R GNG3 GNG3 GCG GCG GPR135 GPR135 CALCB CALCB FAP FAP CALCRL CALCRL RGS5 RGS5 RGS6 RGS6 ADCYAP1R1 ADCYAP1R1 INMT INMT HEXD HEXD HTR2A HTR2A VIP VIP RGS21 RGS21 GLP1R GLP1R HTR5A HTR5A GNAI2 GNAI2 ENSRBIP00000030120 ENSRBIP00000030120 CALCR CALCR RGS3 RGS3 CRHBP CRHBP PTGER1 PTGER1 OPRM1 OPRM1 GNB1 GNB1 GIP GIP GNG8 GNG8 CALCA CALCA RP1 RP1 RAMP2 RAMP2 ENSRBIP00000034184 ENSRBIP00000034184 ADCY5 ADCY5 ADORA2B ADORA2B GNB5 GNB5 SAG SAG PDCL PDCL CRHR1 CRHR1 RGS7 RGS7 MTNR1B MTNR1B RGS11 RGS11 LOC108513979 LOC108513979 GNAL GNAL ADRA2A ADRA2A GNAS GNAS GNAQ GNAQ TAS1R1 TAS1R1 RGS20 RGS20 GNGT2 GNGT2 PLCB2 PLCB2 VIPR2 VIPR2 PLCB4 PLCB4 GHRH GHRH RGS7BP RGS7BP TAS1R3 TAS1R3 GNG10 GNG10 CNR1 CNR1 GNAI3 GNAI3 GIPR GIPR ADM ADM HTR2B HTR2B MTNR1A MTNR1A PTGER2 PTGER2 ADRB2 ADRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR119G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
RGS12Regulator of G protein signaling 12. (1447 aa)
RGS8Regulator of G protein signaling 8. (198 aa)
CRHCorticotropin releasing hormone. (196 aa)
TAS2R5Taste receptor type 2. (299 aa)
TAS1R2Taste 1 receptor member 2. (839 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
FBXO46F-box protein 46. (603 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (489 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
RGS4Regulator of G protein signaling 4. (302 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1629 aa)
RGS9BPRegulator of G protein signaling 9 binding protein. (235 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (476 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
GNA11G protein subunit alpha 11. (354 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
RGS13Regulator of G protein signaling 13. (159 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (457 aa)
PTHLHParathyroid hormone like hormone. (209 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GNB4G protein subunit beta 4. (340 aa)
CASRCalcium sensing receptor. (1078 aa)
RAMP1Receptor activity modifying protein 1. (140 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
IAPPIslet amyloid polypeptide. (86 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
TMIGD3Transmembrane and immunoglobulin domain containing 3; Belongs to the G-protein coupled receptor 1 family. (347 aa)
GNAZG protein subunit alpha z. (355 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
GNA14G protein subunit alpha 14. (355 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
RGS16Regulator of G protein signaling 16. (202 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG13G protein subunit gamma 13. (67 aa)
ENSRBIP00000010613RGS domain-containing protein. (175 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (672 aa)
LTB4R2Leukotriene B4 receptor 2. (389 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (341 aa)
ENSRBIP00000011770Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
GPRC6AG protein-coupled receptor class C group 6 member A. (928 aa)
LRP10LDL receptor related protein 10. (715 aa)
ENSRBIP00000013012Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
RGS14Regulator of G protein signaling 14. (610 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LOC108520845Taste receptor type 2. (309 aa)
PTH2Parathyroid hormone 2. (99 aa)
GNAI1G protein subunit alpha i1. (331 aa)
RIC8ARIC8 guanine nucleotide exchange factor A. (530 aa)
LOC108523537Taste receptor type 2. (310 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
GPR158G protein-coupled receptor 158. (1213 aa)
GNAO1G protein subunit alpha o1. (301 aa)
RGS9Regulator of G protein signaling 9. (674 aa)
GNB2G protein subunit beta 2. (368 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (522 aa)
PLCZ1Phosphoinositide phospholipase C. (550 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
SCTSecretin. (101 aa)
ADM2Adrenomedullin 2. (148 aa)
GNB3G protein subunit beta 3. (340 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
ADRB1Adrenoceptor beta 1; Belongs to the G-protein coupled receptor 1 family. (457 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
LOC108522831PH_14 domain-containing protein. (199 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
RGS18Regulator of G protein signaling 18. (235 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
PDCPhosducin. (246 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
ENSRBIP00000022449Uncharacterized protein. (254 aa)
PTGER3Prostaglandin E receptor 3. (418 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
RGS17Regulator of G protein signaling 17. (210 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (553 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
ENSRBIP00000024798Uncharacterized protein. (54 aa)
TBXA2RThromboxane A2 receptor. (379 aa)
GNA15G protein subunit alpha 15. (312 aa)
RGS1Regulator of G protein signaling 1. (209 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GCGGlucagon. (180 aa)
GPR135G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family. (476 aa)
CALCBCalcitonin related polypeptide beta. (138 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
RGS5Regulator of G protein signaling 5. (201 aa)
RGS6Regulator of G protein signaling 6. (538 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (577 aa)
INMTUncharacterized protein. (244 aa)
HEXDHexosaminidase D. (539 aa)
HTR2A5-hydroxytryptamine receptor 2A. (472 aa)
VIPVasoactive intestinal peptide. (167 aa)
RGS21Regulator of G protein signaling 21. (152 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
HTR5A5-hydroxytryptamine receptor 5A. (345 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ENSRBIP00000030120Uncharacterized protein. (294 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (496 aa)
RGS3Regulator of G protein signaling 3. (916 aa)
CRHBPCorticotropin releasing hormone binding protein. (275 aa)
PTGER1Prostaglandin E receptor 1. (227 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GNB1G protein subunit beta 1. (340 aa)
GIPGastric inhibitory polypeptide. (151 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CALCACalcitonin related polypeptide alpha. (144 aa)
RP1RP1 axonemal microtubule associated. (2131 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
ENSRBIP00000034184G protein gamma domain-containing protein. (68 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (394 aa)
GNB5G protein subunit beta 5. (403 aa)
SAGS-antigen visual arrestin. (405 aa)
PDCLPhosducin like. (301 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
RGS11Regulator of G protein signaling 11. (467 aa)
LOC108513979G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (266 aa)
GNALG protein subunit alpha L. (448 aa)
ADRA2AAdrenoceptor alpha 2A. (400 aa)
GNASGNAS complex locus. (1041 aa)
GNAQG protein subunit alpha q. (359 aa)
TAS1R1Taste receptor type 1 member 1. (841 aa)
RGS20Regulator of G protein signaling 20. (388 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (566 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
GHRHGrowth hormone releasing hormone. (107 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (256 aa)
TAS1R3Taste 1 receptor member 3; Belongs to the G-protein coupled receptor 3 family. (822 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (62 aa)
CNR1Uncharacterized protein. (36 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
ADMAdrenomedullin. (185 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (386 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ADRB2Adrenoceptor beta 2. (399 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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