(5 nodes) Mixed, incl. Dopamine neurotransmitter receptor activity, coupled via Gi/Go, and Guanine nucleotide-binding protein, beta subunit network (Rhinopithecus bieti)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (345 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD3	GNAI3	ENSRBIP00000003961	ENSRBIP00000040755	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha i3.	0.959
DRD3	GNB1	ENSRBIP00000003961	ENSRBIP00000032151	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 1.	0.959
DRD3	GNG7	ENSRBIP00000003961	ENSRBIP00000010095	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.936
GNAI3	DRD3	ENSRBIP00000040755	ENSRBIP00000003961	G protein subunit alpha i3.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.959
GNAI3	GNB1	ENSRBIP00000040755	ENSRBIP00000032151	G protein subunit alpha i3.	G protein subunit beta 1.	0.957
GNAI3	GNG7	ENSRBIP00000040755	ENSRBIP00000010095	G protein subunit alpha i3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.841
GNAI3	HTR5A	ENSRBIP00000040755	ENSRBIP00000030058	G protein subunit alpha i3.	5-hydroxytryptamine receptor 5A.	0.953
GNB1	DRD3	ENSRBIP00000032151	ENSRBIP00000003961	G protein subunit beta 1.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.959
GNB1	GNAI3	ENSRBIP00000032151	ENSRBIP00000040755	G protein subunit beta 1.	G protein subunit alpha i3.	0.957
GNB1	GNG7	ENSRBIP00000032151	ENSRBIP00000010095	G protein subunit beta 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.986
GNB1	HTR5A	ENSRBIP00000032151	ENSRBIP00000030058	G protein subunit beta 1.	5-hydroxytryptamine receptor 5A.	0.952
GNG7	DRD3	ENSRBIP00000010095	ENSRBIP00000003961	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.936
GNG7	GNAI3	ENSRBIP00000010095	ENSRBIP00000040755	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit alpha i3.	0.841
GNG7	GNB1	ENSRBIP00000010095	ENSRBIP00000032151	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 1.	0.986
GNG7	HTR5A	ENSRBIP00000010095	ENSRBIP00000030058	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	5-hydroxytryptamine receptor 5A.	0.932
HTR5A	GNAI3	ENSRBIP00000030058	ENSRBIP00000040755	5-hydroxytryptamine receptor 5A.	G protein subunit alpha i3.	0.953
HTR5A	GNB1	ENSRBIP00000030058	ENSRBIP00000032151	5-hydroxytryptamine receptor 5A.	G protein subunit beta 1.	0.952
HTR5A	GNG7	ENSRBIP00000030058	ENSRBIP00000010095	5-hydroxytryptamine receptor 5A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.932