(46 nodes) Proteoglycan biosynthetic process, and Proteoglycan network (Rhinopithecus bieti)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	HS3ST1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (307 aa)
	CHST7	Sulfotransferase; Belongs to the sulfotransferase 1 family. (486 aa)
	CHPF	Hexosyltransferase. (775 aa)
	CHST12	Carbohydrate sulfotransferase. (414 aa)
	GPC1	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (529 aa)
	PLAC1	Placenta enriched 1. (212 aa)
	HS6ST1	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (411 aa)
	EXT2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
	NDST1	N-deacetylase and N-sulfotransferase 1. (883 aa)
	EXTL3	Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (919 aa)
	CHST11	Carbohydrate sulfotransferase. (352 aa)
	SDC3	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (440 aa)
	GPC6	Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (448 aa)
	CHST3	Sulfotransferase; Belongs to the sulfotransferase 1 family. (465 aa)
	GPC3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (357 aa)
	ENSRBIP00000013978	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (231 aa)
	NDST3	N-deacetylase and N-sulfotransferase 3. (873 aa)
	CSPG4	Chondroitin sulfate proteoglycan 4. (1323 aa)
	SDC1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (338 aa)
	CHSY1	Hexosyltransferase. (752 aa)
	DSE	Dermatan sulfate epimerase. (957 aa)
	XYLT1	Xylosyltransferase 1. (839 aa)
	GPC4	Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (516 aa)
	B4GALT7	Beta-1,4-galactosyltransferase 7. (327 aa)
	EXTL1	Exostosin like glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (636 aa)
	GPC2	Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa)
	BSDC1	BSD domain containing 1. (473 aa)
	HPSE2	Heparanase 2 (inactive). (592 aa)
	B3GALT6	Hexosyltransferase. (266 aa)
	GLCE	Glucuronic acid epimerase. (618 aa)
	EXTL2	Exostosin like glycosyltransferase 2. (337 aa)
	UST	Uronyl 2-sulfotransferase. (356 aa)
	CHST13	Carbohydrate sulfotransferase. (337 aa)
	CHPF2	Hexosyltransferase. (772 aa)
	CSGALNACT2	Hexosyltransferase. (538 aa)
	HPSE	Heparanase. (535 aa)
	HS3ST4	Sulfotransferase; Belongs to the sulfotransferase 1 family. (316 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	HS6ST2	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (315 aa)
	CHSY3	Hexosyltransferase. (882 aa)
	CSGALNACT1	Hexosyltransferase. (532 aa)
	HS2ST1	Heparan sulfate 2-O-sulfotransferase 1. (356 aa)
	HS3ST6	Sulfotransferase; Belongs to the sulfotransferase 1 family. (286 aa)
	SDC2	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
	XYLT2	Xylosyltransferase 2. (849 aa)
	HS3ST5	Sulfotransferase; Belongs to the sulfotransferase 1 family. (346 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GALT6	B4GALT7	ENSRBIP00000031733	ENSRBIP00000023307	Hexosyltransferase.	Beta-1,4-galactosyltransferase 7.	0.968
B3GALT6	DSE	ENSRBIP00000031733	ENSRBIP00000022273	Hexosyltransferase.	Dermatan sulfate epimerase.	0.567
B3GALT6	EXT2	ENSRBIP00000031733	ENSRBIP00000008504	Hexosyltransferase.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.430
B3GALT6	SDC2	ENSRBIP00000031733	ENSRBIP00000042314	Hexosyltransferase.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.499
B3GALT6	XYLT1	ENSRBIP00000031733	ENSRBIP00000022439	Hexosyltransferase.	Xylosyltransferase 1.	0.509
B3GALT6	XYLT2	ENSRBIP00000031733	ENSRBIP00000043076	Hexosyltransferase.	Xylosyltransferase 2.	0.571
B4GALT7	B3GALT6	ENSRBIP00000023307	ENSRBIP00000031733	Beta-1,4-galactosyltransferase 7.	Hexosyltransferase.	0.968
B4GALT7	CHSY1	ENSRBIP00000023307	ENSRBIP00000021792	Beta-1,4-galactosyltransferase 7.	Hexosyltransferase.	0.400
B4GALT7	CHSY3	ENSRBIP00000023307	ENSRBIP00000038935	Beta-1,4-galactosyltransferase 7.	Hexosyltransferase.	0.400
B4GALT7	EXT1	ENSRBIP00000023307	ENSRBIP00000037870	Beta-1,4-galactosyltransferase 7.	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family.	0.424
B4GALT7	EXT2	ENSRBIP00000023307	ENSRBIP00000008504	Beta-1,4-galactosyltransferase 7.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.544
B4GALT7	EXTL3	ENSRBIP00000023307	ENSRBIP00000008696	Beta-1,4-galactosyltransferase 7.	Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.	0.557
B4GALT7	GLCE	ENSRBIP00000023307	ENSRBIP00000032351	Beta-1,4-galactosyltransferase 7.	Glucuronic acid epimerase.	0.563
B4GALT7	GPC1	ENSRBIP00000023307	ENSRBIP00000005116	Beta-1,4-galactosyltransferase 7.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.456
B4GALT7	GPC2	ENSRBIP00000023307	ENSRBIP00000026296	Beta-1,4-galactosyltransferase 7.	Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.456
B4GALT7	GPC3	ENSRBIP00000023307	ENSRBIP00000013122	Beta-1,4-galactosyltransferase 7.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.458
B4GALT7	GPC4	ENSRBIP00000023307	ENSRBIP00000022846	Beta-1,4-galactosyltransferase 7.	Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.456
B4GALT7	GPC6	ENSRBIP00000023307	ENSRBIP00000012302	Beta-1,4-galactosyltransferase 7.	Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.456
B4GALT7	HS2ST1	ENSRBIP00000023307	ENSRBIP00000040993	Beta-1,4-galactosyltransferase 7.	Heparan sulfate 2-O-sulfotransferase 1.	0.451
B4GALT7	NDST1	ENSRBIP00000023307	ENSRBIP00000008528	Beta-1,4-galactosyltransferase 7.	N-deacetylase and N-sulfotransferase 1.	0.400