5 items (Rhinopithecus bieti) - STRING interaction network

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Your Input:
	SENP8	SUMO peptidase family member, NEDD8 specific. (212 aa)
	NEDD8	Ubiquitin-like domain-containing protein. (81 aa)
	UBE2M	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	NAE1	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (538 aa)
	UBA3	Ubiquitin like modifier activating enzyme 3. (463 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NAE1	NEDD8	ENSRBIP00000028043	ENSRBIP00000004182	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin-like domain-containing protein.	0.988
NAE1	SENP8	ENSRBIP00000028043	ENSRBIP00000000767	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	SUMO peptidase family member, NEDD8 specific.	0.850
NAE1	UBA3	ENSRBIP00000028043	ENSRBIP00000041979	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin like modifier activating enzyme 3.	0.999
NAE1	UBE2M	ENSRBIP00000028043	ENSRBIP00000009294	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	0.978
NEDD8	NAE1	ENSRBIP00000004182	ENSRBIP00000028043	Ubiquitin-like domain-containing protein.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.988
NEDD8	SENP8	ENSRBIP00000004182	ENSRBIP00000000767	Ubiquitin-like domain-containing protein.	SUMO peptidase family member, NEDD8 specific.	0.998
NEDD8	UBA3	ENSRBIP00000004182	ENSRBIP00000041979	Ubiquitin-like domain-containing protein.	Ubiquitin like modifier activating enzyme 3.	0.997
NEDD8	UBE2M	ENSRBIP00000004182	ENSRBIP00000009294	Ubiquitin-like domain-containing protein.	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	0.992
SENP8	NAE1	ENSRBIP00000000767	ENSRBIP00000028043	SUMO peptidase family member, NEDD8 specific.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.850
SENP8	NEDD8	ENSRBIP00000000767	ENSRBIP00000004182	SUMO peptidase family member, NEDD8 specific.	Ubiquitin-like domain-containing protein.	0.998
SENP8	UBA3	ENSRBIP00000000767	ENSRBIP00000041979	SUMO peptidase family member, NEDD8 specific.	Ubiquitin like modifier activating enzyme 3.	0.897
SENP8	UBE2M	ENSRBIP00000000767	ENSRBIP00000009294	SUMO peptidase family member, NEDD8 specific.	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	0.469
UBA3	NAE1	ENSRBIP00000041979	ENSRBIP00000028043	Ubiquitin like modifier activating enzyme 3.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.999
UBA3	NEDD8	ENSRBIP00000041979	ENSRBIP00000004182	Ubiquitin like modifier activating enzyme 3.	Ubiquitin-like domain-containing protein.	0.997
UBA3	SENP8	ENSRBIP00000041979	ENSRBIP00000000767	Ubiquitin like modifier activating enzyme 3.	SUMO peptidase family member, NEDD8 specific.	0.897
UBA3	UBE2M	ENSRBIP00000041979	ENSRBIP00000009294	Ubiquitin like modifier activating enzyme 3.	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	0.988
UBE2M	NAE1	ENSRBIP00000009294	ENSRBIP00000028043	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.	0.978
UBE2M	NEDD8	ENSRBIP00000009294	ENSRBIP00000004182	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.992
UBE2M	SENP8	ENSRBIP00000009294	ENSRBIP00000000767	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	SUMO peptidase family member, NEDD8 specific.	0.469
UBE2M	UBA3	ENSRBIP00000009294	ENSRBIP00000041979	Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin like modifier activating enzyme 3.	0.988