(22 nodes) Elongin complex, and SOCS box-like domain superfamily network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSRBIP00000001156	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
	ELOA	Elongin A. (800 aa)
	SOCS4	Suppressor of cytokine signaling 4. (439 aa)
	ELOB	Ubiquitin-like domain-containing protein. (195 aa)
	ENSRBIP00000004787	Skp1_POZ domain-containing protein. (66 aa)
	CUL2	Cullin 2; Belongs to the cullin family. (484 aa)
	LRR1	Leucine rich repeat protein 1. (414 aa)
	SPSB4	SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
	LOC108531561	Ubiquitin-like domain-containing protein. (118 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	ENSRBIP00000015249	Ubiquitin-like domain-containing protein. (137 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (774 aa)
	CISH	Cytokine inducible SH2 containing protein. (255 aa)
	VHL	Von Hippel-Lindau tumor suppressor. (213 aa)
	ENSRBIP00000021753	SOCS box domain-containing protein. (451 aa)
	ELOC	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	ASB5	Ankyrin repeat and SOCS box containing 5. (377 aa)
	ENSRBIP00000030845	annotation not available (44 aa)
	NEURL2	Neuralized E3 ubiquitin protein ligase 2. (285 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (842 aa)
	SPSB2	SplA/ryanodine receptor domain and SOCS box containing 2. (273 aa)
	RNF7	RING-type domain-containing protein. (113 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB5	CUL5	ENSRBIP00000030445	ENSRBIP00000015437	Ankyrin repeat and SOCS box containing 5.	Cullin 5; Belongs to the cullin family.	0.609
ASB5	ELOB	ENSRBIP00000030445	ENSRBIP00000004587	Ankyrin repeat and SOCS box containing 5.	Ubiquitin-like domain-containing protein.	0.508
ASB5	ELOC	ENSRBIP00000030445	ENSRBIP00000029776	Ankyrin repeat and SOCS box containing 5.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.579
ASB5	ENSRBIP00000001156	ENSRBIP00000030445	ENSRBIP00000001156	Ankyrin repeat and SOCS box containing 5.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.579
ASB5	ENSRBIP00000004787	ENSRBIP00000030445	ENSRBIP00000004787	Ankyrin repeat and SOCS box containing 5.	Skp1_POZ domain-containing protein.	0.579
ASB5	ENSRBIP00000015249	ENSRBIP00000030445	ENSRBIP00000015249	Ankyrin repeat and SOCS box containing 5.	Ubiquitin-like domain-containing protein.	0.508
ASB5	LOC108531561	ENSRBIP00000030445	ENSRBIP00000011261	Ankyrin repeat and SOCS box containing 5.	Ubiquitin-like domain-containing protein.	0.508
ASB5	NEURL2	ENSRBIP00000030445	ENSRBIP00000031491	Ankyrin repeat and SOCS box containing 5.	Neuralized E3 ubiquitin protein ligase 2.	0.693
CISH	CUL2	ENSRBIP00000020510	ENSRBIP00000004860	Cytokine inducible SH2 containing protein.	Cullin 2; Belongs to the cullin family.	0.443
CISH	CUL5	ENSRBIP00000020510	ENSRBIP00000015437	Cytokine inducible SH2 containing protein.	Cullin 5; Belongs to the cullin family.	0.927
CISH	ELOB	ENSRBIP00000020510	ENSRBIP00000004587	Cytokine inducible SH2 containing protein.	Ubiquitin-like domain-containing protein.	0.789
CISH	ELOC	ENSRBIP00000020510	ENSRBIP00000029776	Cytokine inducible SH2 containing protein.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.750
CISH	ENSRBIP00000001156	ENSRBIP00000020510	ENSRBIP00000001156	Cytokine inducible SH2 containing protein.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.750
CISH	ENSRBIP00000004787	ENSRBIP00000020510	ENSRBIP00000004787	Cytokine inducible SH2 containing protein.	Skp1_POZ domain-containing protein.	0.750
CISH	ENSRBIP00000015249	ENSRBIP00000020510	ENSRBIP00000015249	Cytokine inducible SH2 containing protein.	Ubiquitin-like domain-containing protein.	0.735
CISH	LOC108531561	ENSRBIP00000020510	ENSRBIP00000011261	Cytokine inducible SH2 containing protein.	Ubiquitin-like domain-containing protein.	0.789
CISH	NEURL2	ENSRBIP00000020510	ENSRBIP00000031491	Cytokine inducible SH2 containing protein.	Neuralized E3 ubiquitin protein ligase 2.	0.486
CISH	RNF7	ENSRBIP00000020510	ENSRBIP00000042976	Cytokine inducible SH2 containing protein.	RING-type domain-containing protein.	0.646
CISH	SOCS4	ENSRBIP00000020510	ENSRBIP00000004436	Cytokine inducible SH2 containing protein.	Suppressor of cytokine signaling 4.	0.484
CISH	SOCS5	ENSRBIP00000020510	ENSRBIP00000012601	Cytokine inducible SH2 containing protein.	Suppressor of cytokine signaling 5.	0.484