STRINGSTRING
BRCA1 BRCA1 ANAPC4 ANAPC4 BARD1 BARD1 ENSRBIP00000040220 ENSRBIP00000040220 CBX7 CBX7 ENSRBIP00000039481 ENSRBIP00000039481 BUB1B BUB1B PCGF1 PCGF1 PCGF5 PCGF5 ANAPC2 ANAPC2 PCGF3 PCGF3 FZR1 FZR1 ANAPC16 ANAPC16 LOC108541777 LOC108541777 BRCA2 BRCA2 ENSRBIP00000001251 ENSRBIP00000001251 ENSRBIP00000001425 ENSRBIP00000001425 ENSRBIP00000002106 ENSRBIP00000002106 ENSRBIP00000002360 ENSRBIP00000002360 CDC20 CDC20 LOC108523335 LOC108523335 PHC3 PHC3 CBX4 CBX4 CDC16 CDC16 BCOR BCOR RAD51 RAD51 ANKRD39 ANKRD39 UBE2C UBE2C CDC27 CDC27 ANAPC5 ANAPC5 ENSRBIP00000024800 ENSRBIP00000024800 CDC23 CDC23 ANAPC13 ANAPC13 FAM89A FAM89A PCGF6 PCGF6 CBX8 CBX8 ANAPC15 ANAPC15 ANAPC10 ANAPC10 LOC108525766 LOC108525766 UBE2S UBE2S PCGF2 PCGF2 ENSRBIP00000015001 ENSRBIP00000015001 ANAPC11 ANAPC11 CBX2 CBX2 BABAM2 BABAM2 RING1 RING1 CDC20B CDC20B CDC26 CDC26 RNF2 RNF2 ANAPC7 ANAPC7 RNF7 RNF7 PHC1 PHC1 ANAPC1 ANAPC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa)
BARD1BRCA1 associated RING domain 1. (771 aa)
ENSRBIP00000040220Uncharacterized protein. (112 aa)
CBX7Chromobox 7. (259 aa)
ENSRBIP00000039481RING-type domain-containing protein. (268 aa)
BUB1BBUB1 N-terminal domain-containing protein. (1050 aa)
PCGF1Polycomb group ring finger 1. (259 aa)
PCGF5Polycomb group ring finger 5. (255 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
PCGF3Polycomb group ring finger 3. (242 aa)
FZR1Fizzy and cell division cycle 20 related 1. (496 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
LOC108541777UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
BRCA2Uncharacterized protein. (386 aa)
ENSRBIP00000001251UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
ENSRBIP00000001425UBIQUITIN_CONJUGAT_2 domain-containing protein. (158 aa)
ENSRBIP00000002106RING-type domain-containing protein. (106 aa)
ENSRBIP00000002360Zf-rbx1 domain-containing protein. (100 aa)
CDC20Cell division cycle 20. (499 aa)
LOC108523335Ubiquitin-conjugating enzyme E2 C. (179 aa)
PHC3Polyhomeotic homolog 3. (872 aa)
CBX4Chromobox 4. (502 aa)
CDC16Cell division cycle 16. (620 aa)
BCORBCL6 corepressor. (1778 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (337 aa)
ANKRD39Ankyrin repeat domain 39. (183 aa)
UBE2CUbiquitin conjugating enzyme E2 C. (179 aa)
CDC27Cell division cycle 27. (803 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
ENSRBIP00000024800DOC domain-containing protein. (124 aa)
CDC23Cell division cycle 23. (597 aa)
ANAPC13Anaphase promoting complex subunit 13. (74 aa)
FAM89AFamily with sequence similarity 89 member A. (175 aa)
PCGF6Polycomb group ring finger 6. (350 aa)
CBX8Chromobox 8. (429 aa)
ANAPC15Anaphase promoting complex subunit 15. (190 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (184 aa)
LOC108525766Uncharacterized protein. (80 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
ENSRBIP00000015001UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
ANAPC11Anaphase promoting complex subunit 11. (180 aa)
CBX2Chromobox 2. (530 aa)
BABAM2BRISC and BRCA1 A complex member 2. (415 aa)
RING1Ring finger protein 1. (387 aa)
CDC20BCell division cycle 20B. (519 aa)
CDC26Cell division cycle 26. (85 aa)
RNF2Ring finger protein 2. (336 aa)
ANAPC7Anaphase promoting complex subunit 7. (498 aa)
RNF7RING-type domain-containing protein. (113 aa)
PHC1Polyhomeotic homolog 1. (1005 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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