STRINGSTRING
CDKN1B CDKN1B ETNK2 ETNK2 RTL5 RTL5 LDOC1 LDOC1 TFEB TFEB ENSRBIP00000001973 ENSRBIP00000001973 FBXW8 FBXW8 CCNF CCNF LIF LIF TCF23 TCF23 PEG10 PEG10 HECTD1 HECTD1 PKD1 PKD1 OVOL2 OVOL2 LOC108515490 LOC108515490 HEY1 HEY1 FZD5 FZD5 GRHL2 GRHL2 ASCL2 ASCL2 PLK4 PLK4 SOX15 SOX15 PLAC1 PLAC1 CPZ-2 CPZ-2 ALKBH1 ALKBH1 SNAI1 SNAI1 STOX2 STOX2 EGLN1 EGLN1 TTPA TTPA HS6ST1 HS6ST1 LEF1 LEF1 ENSRBIP00000009563 ENSRBIP00000009563 GHSR GHSR PRDM1 PRDM1 ENSRBIP00000009976 ENSRBIP00000009976 PTK2 PTK2 LOC108513197 LOC108513197 CEBPA CEBPA AKT1 AKT1 TTPAL TTPAL NR2F2 NR2F2 BIRC2 BIRC2 RTL1 RTL1 CITED2 CITED2 BMPR2 BMPR2 SOCS3 SOCS3 BSG BSG SP3 SP3 HAND1 HAND1 MEN1 MEN1 HNF1A HNF1A KRT19 KRT19 LOC108525138 LOC108525138 FGFR2 FGFR2 MED1 MED1 ADA ADA GCM1 GCM1 STC1 STC1 ADAM19 ADAM19 GRB2 GRB2 VDR VDR ENSRBIP00000016589 ENSRBIP00000016589 CYP27B1 CYP27B1 DEDD DEDD DAZAP1 DAZAP1 PDGFB PDGFB ENSRBIP00000017297 ENSRBIP00000017297 LHX4 LHX4 EPAS1 EPAS1 NSDHL NSDHL CDX4 CDX4 NDP NDP FBN2-2 FBN2-2 CITED1 CITED1 HEY2 HEY2 BIRC6 BIRC6 STK3 STK3 NCOA1 NCOA1 ENSRBIP00000022924 ENSRBIP00000022924 FOSL1 FOSL1 PTGS2 PTGS2 PLCD3 PLCD3 SPP1 SPP1 PCDH12 PCDH12 ENSRBIP00000026358 ENSRBIP00000026358 HTRA1 HTRA1 MAPK1 MAPK1 MAP3K4 MAP3K4 BMP5 BMP5 TPPP3 TPPP3 FBN2 FBN2 DLX3 DLX3 CSF2 CSF2 MAPK14 MAPK14 LOC108540843 LOC108540843 ZFAT ZFAT NODAL NODAL APELA APELA LOC108524163 LOC108524163 GHRL GHRL CDX2 CDX2 CCN1 CCN1 HSD17B2 HSD17B2 TMED2 TMED2 GATA2 GATA2 SETD2 SETD2 RSPO3 RSPO3 ASH1L ASH1L CUL7 CUL7 SPINT1 SPINT1 ZNF568 ZNF568 ZFP36L1 ZFP36L1 PTN PTN WNT7B WNT7B ITGB8 ITGB8 VASH1 VASH1 LHX3 LHX3 PPARD PPARD NOTCH2 NOTCH2 TAF10 TAF10 MDFI MDFI ENSRBIP00000036844 ENSRBIP00000036844 EPOR EPOR E2F8 E2F8 ETV2 ETV2 IGF2 IGF2 HIF1A HIF1A BPTF BPTF EOMES EOMES VASH2 VASH2 CCDC134 CCDC134 ARNT ARNT LEP LEP IL10 IL10 ADM ADM WNT2 WNT2 E2F7 E2F7 RBM15 RBM15 ST14 ST14 PKD2 PKD2 CASP8 CASP8 ENSRBIP00000042716 ENSRBIP00000042716 BMP7 BMP7 TRIM28 TRIM28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ETNK2Ethanolamine kinase 2. (394 aa)
RTL5Retrotransposon Gag like 5. (400 aa)
LDOC1LDOC1 regulator of NFKB signaling. (146 aa)
TFEBTranscription factor EB. (490 aa)
ENSRBIP0000000197340S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
FBXW8F-box and WD repeat domain containing 8. (587 aa)
CCNFCyclin F; Belongs to the cyclin family. (786 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
TCF23Transcription factor 23. (214 aa)
PEG10CCHC-type domain-containing protein. (745 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2472 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4129 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
LOC108515490Retrotransposon Gag like 8B. (113 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)
PLK4Polo like kinase 4. (970 aa)
SOX15SRY-box transcription factor 15. (232 aa)
PLAC1Placenta enriched 1. (212 aa)
CPZ-240S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (229 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
STOX2Storkhead box 2. (925 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (409 aa)
TTPAAlpha tocopherol transfer protein. (278 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (411 aa)
LEF1Lymphoid enhancer binding factor 1. (398 aa)
ENSRBIP00000009563IF rod domain-containing protein; Belongs to the intermediate filament family. (372 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PRDM1PR/SET domain 1. (825 aa)
ENSRBIP0000000997640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (229 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
LOC10851319740S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
CEBPABZIP domain-containing protein. (141 aa)
AKT1AKT serine/threonine kinase 1. (486 aa)
TTPALAlpha tocopherol transfer protein like. (342 aa)
NR2F2NR LBD domain-containing protein. (264 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
RTL1Retrotransposon Gag like 1. (1359 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (253 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SOCS3Uncharacterized protein. (225 aa)
BSGBasigin (Ok blood group). (385 aa)
SP3Sp3 transcription factor. (775 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
MEN1Menin 1. (610 aa)
HNF1AHNF1 homeobox A. (662 aa)
KRT19IF rod domain-containing protein; Belongs to the intermediate filament family. (386 aa)
LOC108525138DUF4939 domain-containing protein. (99 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
ADAA_deaminase domain-containing protein. (443 aa)
GCM1Glial cells missing transcription factor 1. (436 aa)
STC1Stanniocalcin 1. (247 aa)
ADAM19ADAM metallopeptidase domain 19. (838 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
VDRVitamin D receptor. (477 aa)
ENSRBIP00000016589Uncharacterized protein. (267 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
DEDDDeath effector domain containing. (347 aa)
DAZAP1DAZ associated protein 1. (418 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (237 aa)
ENSRBIP00000017297IF rod domain-containing protein; Belongs to the intermediate filament family. (387 aa)
LHX4LIM homeobox 4. (390 aa)
EPAS1Endothelial PAS domain protein 1. (865 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa)
CDX4Caudal type homeobox 4. (280 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
FBN2-2Uncharacterized protein. (341 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
BIRC6Baculoviral IAP repeat containing 6. (4838 aa)
STK3Serine/threonine kinase 3. (490 aa)
NCOA1Nuclear receptor coactivator. (1433 aa)
ENSRBIP00000022924Uncharacterized protein. (571 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
PCDH12Protocadherin 12. (1184 aa)
ENSRBIP0000002635840S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (239 aa)
HTRA1HtrA serine peptidase 1. (451 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1565 aa)
BMP5TGF_BETA_2 domain-containing protein. (154 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
FBN2Fibrillin 2. (2423 aa)
DLX3Distal-less homeobox 3. (287 aa)
CSF2Colony stimulating factor 2. (144 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
LOC10854084340S ribosomal protein S6. (249 aa)
ZFATZinc finger and AT-hook domain containing. (1250 aa)
NODALNodal growth differentiation factor. (347 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
LOC108524163Uncharacterized protein. (383 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
CDX2Caudal type homeobox 2. (313 aa)
CCN1Cellular communication network factor 1. (381 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
GATA2GATA binding protein 2. (468 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
RSPO3R-spondin 3. (293 aa)
ASH1LASH1 like histone lysine methyltransferase. (2894 aa)
CUL7Cullin 7; Belongs to the cullin family. (1763 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (530 aa)
ZNF568Zinc finger protein 568. (646 aa)
ZFP36L1Uncharacterized protein. (327 aa)
PTNPleiotrophin. (168 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (745 aa)
VASH1Vasohibin 1. (365 aa)
LHX3LIM homeobox 3. (409 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
NOTCH2Notch receptor 2. (2532 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (229 aa)
MDFIMyoD family inhibitor. (246 aa)
ENSRBIP00000036844GOLD domain-containing protein. (105 aa)
EPORErythropoietin receptor. (472 aa)
E2F8E2F transcription factor 8. (867 aa)
ETV2ETS variant 2. (370 aa)
IGF2Insulin like growth factor 2. (236 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
BPTFBromodomain PHD finger transcription factor. (2771 aa)
EOMESEomesodermin. (410 aa)
VASH2Vasohibin 2. (355 aa)
CCDC134Coiled-coil domain containing 134. (229 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
IL10Interleukin 10. (178 aa)
ADMAdrenomedullin. (185 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
E2F7E2F transcription factor 7. (910 aa)
RBM15RNA binding motif protein 15. (977 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (958 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
ENSRBIP00000042716A_deaminase domain-containing protein. (344 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TRIM28Tripartite motif containing 28. (746 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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