STRINGSTRING
LDB1 LDB1 TRPC4AP TRPC4AP FGF10 FGF10 TGFB2 TGFB2 KRT28 KRT28 LAMA5 LAMA5 ZMPSTE24 ZMPSTE24 SOSTDC1 SOSTDC1 LRP4 LRP4 FOXN1 FOXN1 SNAI1 SNAI1 FOXE1 FOXE1 ENSRBIP00000008820 ENSRBIP00000008820 SOX9 SOX9 KRT84 KRT84 TP63 TP63 BCL2 BCL2 SHH SHH IGFBP5 IGFBP5 GORAB GORAB ENSRBIP00000014084 ENSRBIP00000014084 FGFR2 FGFR2 ERCC2 ERCC2 LOC108527145 LOC108527145 TMEM79 TMEM79 NSDHL NSDHL RELA RELA ENSRBIP00000018271 ENSRBIP00000018271 DSG4 DSG4 APCDD1 APCDD1 EDAR EDAR INHBA INHBA HDAC1 HDAC1 NOTCH1 NOTCH1 CTNNB1 CTNNB1 FST FST ENSRBIP00000023123 ENSRBIP00000023123 LHX2 LHX2 NSUN2 NSUN2 HDAC2 HDAC2 DKK1 DKK1 LDB2 LDB2 NOM1 NOM1 ACVR1B ACVR1B FGF7 FGF7 DLX3 DLX3 KRT71 KRT71 ALX4 ALX4 FUZ FUZ INTU INTU EDA EDA FZD3 FZD3 SOS1 SOS1 TNFRSF19 TNFRSF19 ZDHHC21 ZDHHC21 SAV1 SAV1 KRT27 KRT27 GNAS GNAS PIAS4 PIAS4 EXT1 EXT1 LGR4 LGR4 ENSRBIP00000038500 ENSRBIP00000038500 CD109 CD109 DNASE1L2 DNASE1L2 SMO SMO LOC108541626 LOC108541626 KRT25 KRT25 FZD6 FZD6 LGR5 LGR5 NF1 NF1 GLI2 GLI2 NGFR NGFR PUM2 PUM2 HOXC13 HOXC13 WNT10A WNT10A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LDB1LIM domain binding 1. (411 aa)
TRPC4APTransient receptor potential cation channel subfamily C member 4 associated protein. (698 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
KRT28Keratin 28; Belongs to the intermediate filament family. (464 aa)
LAMA5Laminin subunit alpha 5. (3606 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (441 aa)
SOSTDC1Sclerostin domain containing 1. (230 aa)
LRP4LDL receptor related protein 4. (1686 aa)
FOXN1Forkhead box N1. (648 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
FOXE1Forkhead box E1. (337 aa)
ENSRBIP00000008820Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa)
SOX9SRY-box transcription factor 9. (305 aa)
KRT84Keratin 84; Belongs to the intermediate filament family. (600 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
IGFBP5Insulin like growth factor binding protein 5. (260 aa)
GORABGolgin, RAB6 interacting. (393 aa)
ENSRBIP00000014084Uncharacterized protein. (147 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (675 aa)
LOC108527145Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
TMEM79Uncharacterized protein. (354 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa)
RELAUncharacterized protein. (282 aa)
ENSRBIP00000018271Hist_deacetyl domain-containing protein. (180 aa)
DSG4Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1055 aa)
APCDD1APC down-regulated 1. (514 aa)
EDAREctodysplasin A receptor. (496 aa)
INHBAInhibin subunit beta A. (426 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
NOTCH1Notch receptor 1. (2438 aa)
CTNNB1Catenin beta 1. (781 aa)
FSTFollistatin. (333 aa)
ENSRBIP00000023123Uncharacterized protein. (391 aa)
LHX2LIM homeobox 2. (406 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (767 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
LDB2LIM domain binding 2. (373 aa)
NOM1Nucleolar protein with MIF4G domain 1. (863 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
DLX3Distal-less homeobox 3. (287 aa)
KRT71Keratin 71; Belongs to the intermediate filament family. (525 aa)
ALX4ALX homeobox 4. (409 aa)
FUZFuzzy planar cell polarity protein. (368 aa)
INTUInturned planar cell polarity protein. (933 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (234 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1293 aa)
TNFRSF19TNF receptor superfamily member 19. (416 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
KRT27Keratin 27; Belongs to the intermediate filament family. (459 aa)
GNASGNAS complex locus. (1041 aa)
PIAS4Protein inhibitor of activated STAT 4. (508 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (931 aa)
ENSRBIP00000038500RHD domain-containing protein. (112 aa)
CD109CD109 molecule. (1404 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
LOC108541626Uncharacterized protein. (246 aa)
KRT25Keratin 25; Belongs to the intermediate filament family. (450 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
NF1Neurofibromin 1. (2822 aa)
GLI2GLI family zinc finger 2. (1581 aa)
NGFRNerve growth factor receptor. (427 aa)
PUM2Pumilio RNA binding family member 2. (1065 aa)
HOXC13Homeobox C13. (330 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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