STRINGSTRING
RNF113A RNF113A SAMHD1 SAMHD1 OAS1 OAS1 NR1H3 NR1H3 CCDC3 CCDC3 SOCS1 SOCS1 CACTIN CACTIN LOC108526638 LOC108526638 ENSRBIP00000002079 ENSRBIP00000002079 PTPN1 PTPN1 USP27X USP27X OTULIN OTULIN NLRP2 NLRP2 RIPK2 RIPK2 TRAIP TRAIP IKBKE IKBKE LSM14A LSM14A GPS2 GPS2 DCST1 DCST1 PADI2 PADI2 TRIM56 TRIM56 GAS6 GAS6 IRAK3 IRAK3 TSLP TSLP ENSRBIP00000007280 ENSRBIP00000007280 OAS3 OAS3 ENSRBIP00000007353 ENSRBIP00000007353 PRKN PRKN ROBO1 ROBO1 HIPK1 HIPK1 IL1R1 IL1R1 ENSRBIP00000009622 ENSRBIP00000009622 ENSRBIP00000009767 ENSRBIP00000009767 CNOT7 CNOT7 SPATA2 SPATA2 RNF185 RNF185 ADIPOQ ADIPOQ ECM1 ECM1 TRIM44 TRIM44 ENSRBIP00000012180 ENSRBIP00000012180 AGPAT1 AGPAT1 PELI3 PELI3 IRF3 IRF3 H2BC11 H2BC11 TRIM32 TRIM32 ENSRBIP00000013354 ENSRBIP00000013354 SIGIRR SIGIRR ADAM17 ADAM17 MED1 MED1 AXL AXL SLIT2 SLIT2 CAV1 CAV1 SLIT3 SLIT3 METTL3 METTL3 RFFL RFFL MMP12 MMP12 PPP2CB PPP2CB ENSRBIP00000016878 ENSRBIP00000016878 CSF1 CSF1 NR1H4 NR1H4 NLRP6 NLRP6 AGPAT2 AGPAT2 OTOP1 OTOP1 TXK TXK MAVS MAVS NOL3 NOL3 CD300LF CD300LF DNAJA3 DNAJA3 ENSRBIP00000022247 ENSRBIP00000022247 OTUD4 OTUD4 NR1H2 NR1H2 NAIP NAIP SYK SYK STING1 STING1 PALM3 PALM3 RNF113B RNF113B IL1RN IL1RN UBE2K UBE2K CYLD CYLD STAP1 STAP1 GFI1 GFI1 YTHDF3 YTHDF3 SPHK1 SPHK1 CASP4 CASP4 RABGEF1 RABGEF1 FADD FADD ZNF675 ZNF675 IRAK1 IRAK1 ENSRBIP00000026419 ENSRBIP00000026419 EDN1 EDN1 PXDN PXDN PTPN11 PTPN11 CDC37 CDC37 TREM2 TREM2 IL7 IL7 IKBKB IKBKB ARG1 ARG1 LOC108515415 LOC108515415 IRAK2 IRAK2 ISG15 ISG15 TRIM41 TRIM41 PTPN2 PTPN2 TBK1 TBK1 TRAF2 TRAF2 CASP1 CASP1 SH2B3 SH2B3 ENSRBIP00000031653 ENSRBIP00000031653 HPX HPX ENSRBIP00000032719 ENSRBIP00000032719 LOC108516810 LOC108516810 STAT2 STAT2 LOC108526807 LOC108526807 C1QTNF4 C1QTNF4 CARD16 CARD16 NKIRAS2 NKIRAS2 NLRC5 NLRC5 SHARPIN SHARPIN LOC108513176 LOC108513176 PYDC1 PYDC1 IL1R2 IL1R2 PIAS4 PIAS4 ANGPT1 ANGPT1 PARP14 PARP14 CD74 CD74 PYCARD PYCARD TTLL12 TTLL12 HIF1A HIF1A TNFRSF1A TNFRSF1A PTPN6 PTPN6 ENSRBIP00000039905 ENSRBIP00000039905 ENSRBIP00000040005 ENSRBIP00000040005 SPPL2A SPPL2A PTPRC PTPRC PARP9 PARP9 YTHDF2 YTHDF2 WNT5A WNT5A MUL1 MUL1 RIPK1 RIPK1 LOC108541675 LOC108541675 CASP8 CASP8 VRK2 VRK2 ZBP1 ZBP1 BIRC7 BIRC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF113ARing finger protein 113A. (343 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (628 aa)
OAS12'-5'-oligoadenylate synthetase 1. (408 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (441 aa)
CCDC3Coiled-coil domain containing 3. (270 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
CACTINCactin, spliceosome C complex subunit. (804 aa)
LOC108526638A to I editase domain-containing protein. (193 aa)
ENSRBIP00000002079Uncharacterized protein. (202 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
NLRP2NLR family pyrin domain containing 2. (1014 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
TRAIPTRAF interacting protein. (284 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
LSM14AUncharacterized protein. (401 aa)
GPS2G protein pathway suppressor 2. (327 aa)
DCST1DC-STAMP domain containing 1. (706 aa)
PADI2Peptidyl arginine deiminase 2. (723 aa)
TRIM56Tripartite motif containing 56. (755 aa)
GAS6Growth arrest specific 6. (623 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
TSLPThymic stromal lymphopoietin. (159 aa)
ENSRBIP00000007280Tyrosine-protein phosphatase non-receptor type. (354 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1092 aa)
ENSRBIP00000007353A20-type domain-containing protein. (128 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ROBO1Roundabout guidance receptor 1. (1621 aa)
HIPK1Homeodomain interacting protein kinase 1. (1417 aa)
IL1R1Interleukin 1 receptor type 1. (568 aa)
ENSRBIP00000009622Uncharacterized protein. (329 aa)
ENSRBIP00000009767Uncharacterized protein. (546 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
RNF185Ring finger protein 185. (195 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
ECM1Extracellular matrix protein 1. (540 aa)
TRIM44Tripartite motif containing 44. (289 aa)
ENSRBIP00000012180Uncharacterized protein. (348 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (283 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (397 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (426 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
TRIM32Tripartite motif containing 32. (653 aa)
ENSRBIP00000013354IRF-3 domain-containing protein. (139 aa)
SIGIRRSingle Ig and TIR domain containing. (502 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
AXLAXL receptor tyrosine kinase. (892 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (363 aa)
MMP12Matrix metallopeptidase 12. (475 aa)
PPP2CBSerine/threonine-protein phosphatase. (304 aa)
ENSRBIP00000016878Uncharacterized protein. (251 aa)
CSF1Colony stimulating factor 1. (587 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (481 aa)
NLRP6NLR family pyrin domain containing 6. (1041 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (278 aa)
OTOP1Otopetrin 1. (610 aa)
TXKTyrosine-protein kinase. (498 aa)
MAVSMitochondrial antiviral signaling protein. (539 aa)
NOL3CARD domain-containing protein. (271 aa)
CD300LFCD300 molecule like family member f. (306 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
OTUD4OTU deubiquitinase 4. (1100 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
NAIPNLR family apoptosis inhibitory protein. (1395 aa)
SYKUncharacterized protein. (331 aa)
STING1Transmembrane protein 173. (379 aa)
PALM3Paralemmin 3. (693 aa)
RNF113BRing finger protein 113B. (322 aa)
IL1RNInterleukin-1. (179 aa)
UBE2KUbiquitin conjugating enzyme E2 K. (190 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (948 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (588 aa)
SPHK1Sphingosine kinase 1. (384 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (376 aa)
RABGEF1Uncharacterized protein. (430 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ZNF675Zinc finger protein 675. (530 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (702 aa)
ENSRBIP00000026419Uncharacterized protein. (249 aa)
EDN1Endothelin 1. (211 aa)
PXDNPeroxidasin. (1454 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
CDC37Cell division cycle 37. (378 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (231 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (171 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
ARG1Arginase. (322 aa)
LOC108515415CARD domain-containing protein. (201 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (537 aa)
ISG15ISG15 ubiquitin like modifier. (167 aa)
TRIM41Tripartite motif containing 41. (612 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
TBK1TANK binding kinase 1. (681 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
SH2B3SH2B adaptor protein 3. (568 aa)
ENSRBIP00000031653Uncharacterized protein. (70 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
ENSRBIP00000032719SH2 domain-containing protein. (203 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
STAT2Signal transducer and activator of transcription. (844 aa)
LOC108526807Uncharacterized protein. (756 aa)
C1QTNF4C1q and TNF related 4. (316 aa)
CARD16Caspase recruitment domain family member 16. (197 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (231 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
SHARPINSHANK associated RH domain interactor. (384 aa)
LOC108513176Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa)
PYDC1Pyrin domain containing 1. (89 aa)
IL1R2Interleukin 1 receptor type 2. (397 aa)
PIAS4Protein inhibitor of activated STAT 4. (508 aa)
ANGPT1Angiopoietin 1. (498 aa)
PARP14Poly [ADP-ribose] polymerase. (1800 aa)
CD74CD74 molecule. (294 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TTLL12Tubulin tyrosine ligase like 12. (648 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
ENSRBIP00000039905VPS9 domain-containing protein. (259 aa)
ENSRBIP00000040005Uncharacterized protein. (257 aa)
SPPL2ASignal peptide peptidase like 2A. (422 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (749 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (579 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (672 aa)
LOC108541675Uncharacterized protein. (423 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
VRK2VRK serine/threonine kinase 2. (500 aa)
ZBP1Z-DNA binding protein 1. (451 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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