STRINGSTRING
OAS1 OAS1 TLR2 TLR2 LRRC19 LRRC19 LY96 LY96 TNIP2 TNIP2 NLRC4 NLRC4 TRIL TRIL TIFA TIFA AP3B1 AP3B1 LOC108534534 LOC108534534 NOD2 NOD2 OTULIN OTULIN RIPK2 RIPK2 SCIMP SCIMP LSM14A LSM14A TLR7 TLR7 ENSRBIP00000005518 ENSRBIP00000005518 RAB11FIP2 RAB11FIP2 TLR4 TLR4 IRAK3 IRAK3 TNIP1 TNIP1 MASP2 MASP2 OAS3 OAS3 FFAR2 FFAR2 TNIP3 TNIP3 TLR3 TLR3 ENSRBIP00000007889 ENSRBIP00000007889 CLPB CLPB REG3G REG3G DHX58 DHX58 MYD88 MYD88 CLEC4E CLEC4E IFIH1 IFIH1 HAVCR2 HAVCR2 TLR10 TLR10 MAPKAPK3 MAPKAPK3 IRF3 IRF3 LINGO3 LINGO3 PLCG2 PLCG2 ENSRBIP00000013354 ENSRBIP00000013354 RPS6KA3 RPS6KA3 COLEC10 COLEC10 RFTN1 RFTN1 MASP1 MASP1 AIM2 AIM2 COLEC12 COLEC12 RNF135 RNF135 RELA RELA NR1H4 NR1H4 TIRAP TIRAP MBL2 MBL2 FCN2 FCN2 MAP2K6 MAP2K6 EPG5 EPG5 CD300LF CD300LF CTSS CTSS TLR1 TLR1 ENSRBIP00000022247 ENSRBIP00000022247 CD14 CD14 REG3A REG3A ALPK1 ALPK1 NAIP NAIP NMI NMI ITCH ITCH TLR8 TLR8 TICAM1 TICAM1 PYDC5 PYDC5 IRF7 IRF7 IRAK1 IRAK1 PIK3AP1 PIK3AP1 S100A14 S100A14 TLR9 TLR9 IRAK2 IRAK2 OTULINL OTULINL CASP1 CASP1 NOD1 NOD1 DDX58 DDX58 UNC93B1 UNC93B1 MAPKAPK2 MAPKAPK2 INAVA INAVA LOC108513176 LOC108513176 MEFV MEFV LYN LYN LACC1 LACC1 NLRP1 NLRP1 FCN3 FCN3 ENSRBIP00000038500 ENSRBIP00000038500 PYCARD PYCARD IRAK4 IRAK4 NFKBIA NFKBIA PRKCE PRKCE BCL10 BCL10 LOC108541675 LOC108541675 TRAF3 TRAF3 BTK BTK ENSRBIP00000042683 ENSRBIP00000042683 ENSRBIP00000042840 ENSRBIP00000042840 PHB PHB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OAS12'-5'-oligoadenylate synthetase 1. (408 aa)
TLR2Toll-like receptor. (784 aa)
LRRC19Leucine rich repeat containing 19. (370 aa)
LY96Lymphocyte antigen 96. (160 aa)
TNIP2CCHC NOA-type domain-containing protein. (337 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
TRILTLR4 interactor with leucine rich repeats. (811 aa)
TIFATRAF interacting protein with forkhead associated domain. (185 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1067 aa)
LOC108534534Prohibitin. (272 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (143 aa)
LSM14AUncharacterized protein. (401 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
ENSRBIP00000005518Prohibitin. (152 aa)
RAB11FIP2RAB11 family interacting protein 2. (512 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
TNIP1TNFAIP3 interacting protein 1. (637 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1092 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
TNIP3TNFAIP3 interacting protein 3. (383 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
ENSRBIP00000007889Fibrinogen C-terminal domain-containing protein. (317 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)
REG3GRegenerating family member 3 gamma. (174 aa)
DHX58DExH-box helicase 58. (678 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
IFIH1Interferon induced with helicase C domain 1. (1014 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
TLR10Toll like receptor 10; Belongs to the Toll-like receptor family. (811 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (434 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (426 aa)
LINGO3Leucine rich repeat and Ig domain containing 3. (572 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ENSRBIP00000013354IRF-3 domain-containing protein. (139 aa)
RPS6KA3Uncharacterized protein. (66 aa)
COLEC10Collectin subfamily member 10. (276 aa)
RFTN1Raftlin, lipid raft linker 1. (578 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (739 aa)
AIM2Absent in melanoma 2. (343 aa)
COLEC12Collectin subfamily member 12. (721 aa)
RNF135Ring finger protein 135. (421 aa)
RELAUncharacterized protein. (282 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (481 aa)
TIRAPTIR domain containing adaptor protein. (233 aa)
MBL2Mannose binding lectin 2. (247 aa)
FCN2Ficolin 2. (328 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2582 aa)
CD300LFCD300 molecule like family member f. (306 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
TLR1Toll like receptor 1. (703 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
CD14CD14 molecule. (384 aa)
REG3ARegenerating family member 3 alpha. (175 aa)
ALPK1Alpha kinase 1. (1245 aa)
NAIPNLR family apoptosis inhibitory protein. (1395 aa)
NMIN-myc and STAT interactor. (307 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1016 aa)
TICAM1Toll like receptor adaptor molecule 1. (515 aa)
PYDC5Uncharacterized protein. (101 aa)
IRF7Interferon regulatory factor 7. (503 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (702 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (807 aa)
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)
TLR9TIR domain-containing protein. (1033 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (537 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (356 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
DDX58DExD/H-box helicase 58. (914 aa)
UNC93B1Unc-93 homolog B1, TLR signaling regulator. (597 aa)
MAPKAPK2MAPK activated protein kinase 2. (392 aa)
INAVAInnate immunity activator. (703 aa)
LOC108513176Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa)
MEFVMEFV innate immuity regulator, pyrin. (784 aa)
LYNTyrosine-protein kinase. (512 aa)
LACC1Uncharacterized protein. (430 aa)
NLRP1NLR family pyrin domain containing 1. (1476 aa)
FCN3Ficolin 3. (320 aa)
ENSRBIP00000038500RHD domain-containing protein. (112 aa)
PYCARDPYD and CARD domain containing. (195 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (461 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
LOC108541675Uncharacterized protein. (423 aa)
TRAF3TNF receptor-associated factor. (477 aa)
BTKTyrosine-protein kinase. (673 aa)
ENSRBIP00000042683Prohibitin. (189 aa)
ENSRBIP00000042840Prohibitin. (259 aa)
PHBProhibitin. (272 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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