STRINGSTRING
UBE2K UBE2K LOC108540315 LOC108540315 HLA-E HLA-E IL17F IL17F PYDC5 PYDC5 CRTAM CRTAM FADD FADD SH2D1B SH2D1B IKBKB IKBKB NONO NONO ARG1 ARG1 ENSRBIP00000028707 ENSRBIP00000028707 PGC PGC CADM1 CADM1 TRIM41 TRIM41 CREBBP CREBBP TBK1 TBK1 XRCC6 XRCC6 KIR2DL4 KIR2DL4 HPX HPX IL12A IL12A MIF MIF IFI35 IFI35 KLRK1 KLRK1 HSP90AA1 HSP90AA1 MMRN2 MMRN2 NMI NMI HLA-F HLA-F STING1 STING1 SYK SYK CLEC6A CLEC6A POLR3C POLR3C POLR3D POLR3D LOC108531166 LOC108531166 SFPQ SFPQ ENSRBIP00000022670 ENSRBIP00000022670 CD14 CD14 RIOK3 RIOK3 NCR3 NCR3 TRIM15 TRIM15 MATR3 MATR3 PAK2 PAK2 SASH1 SASH1 KLK7 KLK7 LAG3 LAG3 GRN GRN DDX60 DDX60 PAK1 PAK1 FBXO38 FBXO38 LOC108537061 LOC108537061 CGAS CGAS FCN2 FCN2 PRKCA PRKCA MAVS MAVS MBL2 MBL2 IFI16 IFI16 EMILIN1 EMILIN1 TXK TXK ADAM8 ADAM8 SLC22A13 SLC22A13 TIRAP TIRAP ACOD1 ACOD1 PQBP1 PQBP1 LOC108541675 LOC108541675 IL21 IL21 IL17A IL17A TRIM62 TRIM62 ZBP1 ZBP1 ENSRBIP00000043094 ENSRBIP00000043094 PUM2 PUM2 CD226 CD226 KIR3DL3 KIR3DL3 XRCC5 XRCC5 CD180 CD180 MMP12 MMP12 STAT5B STAT5B AIM2 AIM2 LY86 LY86 POLR3B POLR3B MED1 MED1 KLK5 KLK5 MASP1 MASP1 NLRP10 NLRP10 LOC108516810 LOC108516810 ENSRBIP00000033534 ENSRBIP00000033534 EP300 EP300 ENSRBIP00000034107 ENSRBIP00000034107 ENSRBIP00000034349 ENSRBIP00000034349 POLR3G POLR3G VAV1 VAV1 SIN3A SIN3A ZNFX1 ZNFX1 MNDA MNDA NLRC5 NLRC5 EMILIN2 EMILIN2 TYROBP TYROBP ENSRBIP00000041364 ENSRBIP00000041364 WNT5A WNT5A PARP9 PARP9 SLC15A4 SLC15A4 TRAF6 TRAF6 LYN LYN ENSRBIP00000036862 ENSRBIP00000036862 ANKRD17 ANKRD17 LBP LBP RASGRP1 RASGRP1 COLEC10 COLEC10 PRKDC PRKDC BMP6 BMP6 ENSRBIP00000013354 ENSRBIP00000013354 PLCG2 PLCG2 ENSRBIP00000013166 ENSRBIP00000013166 IRF3 IRF3 PLA2G5 PLA2G5 CD160 CD160 PYHIN1 PYHIN1 MR1 MR1 TRIM5 TRIM5 ZCCHC3 ZCCHC3 CYBA CYBA ENSRBIP00000011182 ENSRBIP00000011182 RNF185 RNF185 HAVCR2 HAVCR2 DHX58 DHX58 CARD9 CARD9 CASP6 CASP6 ENSRBIP00000009551 ENSRBIP00000009551 NECTIN2 NECTIN2 CLNK CLNK EREG EREG RBM14 RBM14 ENSRBIP00000007889 ENSRBIP00000007889 FFAR2 FFAR2 MASP2 MASP2 ENSRBIP00000007185 ENSRBIP00000007185 ENSRBIP00000006958 ENSRBIP00000006958 HEXIM1 HEXIM1 TLR4 TLR4 FYN FYN KLRD1 KLRD1 AKIRIN2 AKIRIN2 ENSRBIP00000005739 ENSRBIP00000005739 COCH COCH TRIM56 TRIM56 LSM14A LSM14A POLR3F POLR3F IKBKE IKBKE ENSRBIP00000004373 ENSRBIP00000004373 SCIMP SCIMP LOC108543093 LOC108543093 NOD2 NOD2 PVR PVR USP27X USP27X PLSCR1 PLSCR1 SRC SRC ENSRBIP00000001755 ENSRBIP00000001755 OASL OASL NLRC4 NLRC4 CXorf21 CXorf21 SH2D1A SH2D1A LY96 LY96 HRG HRG ENSRBIP00000000175 ENSRBIP00000000175 PUM1 PUM1 FCN3 FCN3 USP15 USP15 PYCARD PYCARD LAMP1 LAMP1 SLAMF6 SLAMF6 LOC108536663 LOC108536663 TLR8 TLR8 TOMM70 TOMM70 PSPC1 PSPC1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2KUbiquitin conjugating enzyme E2 K. (190 aa)
LOC108540315Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (233 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (359 aa)
IL17FInterleukin 17F. (163 aa)
PYDC5Uncharacterized protein. (101 aa)
CRTAMCytotoxic and regulatory T cell molecule. (344 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
SH2D1BSH2 domain containing 1B. (132 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
NONONon-POU domain containing octamer binding. (366 aa)
ARG1Arginase. (322 aa)
ENSRBIP00000028707U1-type domain-containing protein. (493 aa)
PGCProgastricsin; Belongs to the peptidase A1 family. (388 aa)
CADM1Cell adhesion molecule 1. (473 aa)
TRIM41Tripartite motif containing 41. (612 aa)
CREBBPCREB binding protein. (2422 aa)
TBK1TANK binding kinase 1. (681 aa)
XRCC6X-ray repair cross complementing 6. (568 aa)
KIR2DL4Uncharacterized protein. (357 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
MIFUncharacterized protein. (115 aa)
IFI35Interferon induced protein 35. (277 aa)
KLRK1Killer cell lectin like receptor K1. (204 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (686 aa)
MMRN2Multimerin 2. (951 aa)
NMIN-myc and STAT interactor. (307 aa)
HLA-FMajor histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa)
STING1Transmembrane protein 173. (379 aa)
SYKUncharacterized protein. (331 aa)
CLEC6AC-type lectin domain containing 6A. (209 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
POLR3DRNA polymerase III subunit D. (471 aa)
LOC108531166AIG1-type G domain-containing protein. (307 aa)
SFPQSplicing factor proline and glutamine rich. (640 aa)
ENSRBIP00000022670Uncharacterized protein. (281 aa)
CD14CD14 molecule. (384 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (603 aa)
NCR3Natural cytotoxicity triggering receptor 3. (180 aa)
TRIM15Tripartite motif containing 15. (465 aa)
MATR3Uncharacterized protein. (559 aa)
PAK2Non-specific serine/threonine protein kinase. (539 aa)
SASH1SAM and SH3 domain containing 1. (1246 aa)
KLK7Kallikrein related peptidase 7. (169 aa)
LAG3Lymphocyte activating 3. (525 aa)
GRNGranulin precursor. (593 aa)
DDX60DExD/H-box helicase 60. (1612 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
FBXO38F-box protein 38. (1188 aa)
LOC108537061HATPase_c domain-containing protein. (384 aa)
CGASCyclic GMP-AMP synthase. (527 aa)
FCN2Ficolin 2. (328 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
MAVSMitochondrial antiviral signaling protein. (539 aa)
MBL2Mannose binding lectin 2. (247 aa)
IFI16Interferon gamma inducible protein 16. (729 aa)
EMILIN1Elastin microfibril interfacer 1. (620 aa)
TXKTyrosine-protein kinase. (498 aa)
ADAM8ADAM metallopeptidase domain 8. (755 aa)
SLC22A13Solute carrier family 22 member 13. (551 aa)
TIRAPTIR domain containing adaptor protein. (233 aa)
ACOD1Aconitate decarboxylase 1. (458 aa)
PQBP1Polyglutamine binding protein 1. (265 aa)
LOC108541675Uncharacterized protein. (423 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL17AInterleukin 17A. (155 aa)
TRIM62Tripartite motif containing 62. (475 aa)
ZBP1Z-DNA binding protein 1. (451 aa)
ENSRBIP00000043094Uncharacterized protein. (97 aa)
PUM2Pumilio RNA binding family member 2. (1065 aa)
CD226CD226 molecule. (356 aa)
KIR3DL3Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (428 aa)
XRCC5X-ray repair cross complementing 5. (805 aa)
CD180CD180 molecule. (661 aa)
MMP12Matrix metallopeptidase 12. (475 aa)
STAT5BSignal transducer and activator of transcription. (768 aa)
AIM2Absent in melanoma 2. (343 aa)
LY86Lymphocyte antigen 86. (188 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1123 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (739 aa)
NLRP10NLR family pyrin domain containing 10. (626 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
ENSRBIP00000033534MHC_I-like_Ag-recog domain-containing protein. (227 aa)
EP300E1A binding protein p300. (2296 aa)
ENSRBIP00000034107HATPase_c domain-containing protein. (638 aa)
ENSRBIP00000034349Matrin-type domain-containing protein. (227 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
VAV1Vav guanine nucleotide exchange factor 1. (843 aa)
SIN3ASIN3 transcription regulator family member A. (1228 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1915 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
EMILIN2Elastin microfibril interfacer 2. (831 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (112 aa)
ENSRBIP00000041364Ku domain-containing protein. (498 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (749 aa)
SLC15A4Solute carrier family 15 member 4. (496 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
LYNTyrosine-protein kinase. (512 aa)
ENSRBIP00000036862Ku domain-containing protein. (567 aa)
ANKRD17Ankyrin repeat domain 17. (2572 aa)
LBPLipopolysaccharide binding protein. (481 aa)
RASGRP1RAS guanyl releasing protein 1. (841 aa)
COLEC10Collectin subfamily member 10. (276 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
BMP6Bone morphogenetic protein 6. (440 aa)
ENSRBIP00000013354IRF-3 domain-containing protein. (139 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ENSRBIP00000013166Uncharacterized protein. (117 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (426 aa)
PLA2G5Phospholipase A(2). (138 aa)
CD160CD160 molecule. (232 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (340 aa)
TRIM5Uncharacterized protein. (486 aa)
ZCCHC3Zinc finger CCHC-type containing 3. (402 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
ENSRBIP00000011182Ku domain-containing protein. (328 aa)
RNF185Ring finger protein 185. (195 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
DHX58DExH-box helicase 58. (678 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (288 aa)
ENSRBIP00000009551Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (318 aa)
NECTIN2Nectin cell adhesion molecule 2. (573 aa)
CLNKCytokine dependent hematopoietic cell linker. (428 aa)
EREGEpiregulin. (169 aa)
RBM14RNA binding motif protein 14. (669 aa)
ENSRBIP00000007889Fibrinogen C-terminal domain-containing protein. (317 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
ENSRBIP00000007185Ig-like domain-containing protein; Belongs to the MHC class I family. (392 aa)
ENSRBIP00000006958TNF receptor-associated factor. (473 aa)
HEXIM1Uncharacterized protein. (359 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
FYNTyrosine-protein kinase. (537 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
AKIRIN2Akirin 2. (203 aa)
ENSRBIP00000005739Uncharacterized protein. (212 aa)
COCHCochlin. (580 aa)
TRIM56Tripartite motif containing 56. (755 aa)
LSM14AUncharacterized protein. (401 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
ENSRBIP00000004373Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (143 aa)
LOC108543093Ig-like domain-containing protein; Belongs to the MHC class I family. (378 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
PVRIg-like domain-containing protein. (240 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (326 aa)
SRCTyrosine-protein kinase. (627 aa)
ENSRBIP00000001755Uncharacterized protein. (218 aa)
OASL2'-5'-oligoadenylate synthetase like. (449 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
CXorf21Chromosome X open reading frame 21. (301 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
LY96Lymphocyte antigen 96. (160 aa)
HRGHistidine rich glycoprotein. (530 aa)
ENSRBIP00000000175MHC_I-like_Ag-recog domain-containing protein. (233 aa)
PUM1Pumilio RNA binding family member 1. (1223 aa)
FCN3Ficolin 3. (320 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (880 aa)
PYCARDPYD and CARD domain containing. (195 aa)
LAMP1Lysosomal associated membrane protein 1. (415 aa)
SLAMF6SLAM family member 6. (332 aa)
LOC108536663MHC_I-like_Ag-recog domain-containing protein. (299 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1016 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
PSPC1Paraspeckle component 1. (487 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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