Your Input: | |
| | LOC108521487 | BIVM-ERCC5 readthrough. (1654 aa) |
| | NEIL3 | Nei like DNA glycosylase 3. (594 aa) |
| | SSBP4 | Single stranded DNA binding protein 4. (381 aa) |
| | ENSRBIP00000004884 | Uncharacterized protein. (162 aa) |
| | PURB | Purine rich element binding protein B. (312 aa) |
| | NABP1 | Nucleic acid binding protein 1. (204 aa) |
| | HNRNPA2B1 | Heterogeneous nuclear ribonucleoprotein A2/B1. (353 aa) |
| | FAM111A | Family with sequence similarity 111 member A. (611 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (613 aa) |
| | TEN1 | Uncharacterized protein. (123 aa) |
| | POLR2G | RNA polymerase II subunit G. (172 aa) |
| | SMC2 | Structural maintenance of chromosomes protein. (1197 aa) |
| | ENSRBIP00000000804 | RPA_C domain-containing protein. (235 aa) |
| | BRCA2 | Uncharacterized protein. (386 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (628 aa) |
| | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (232 aa) |
| | SMC6 | Structural maintenance of chromosomes 6. (1040 aa) |
| | POLR2H | RNA polymerase II subunit H. (174 aa) |
| | LOC108537870 | Uncharacterized protein. (322 aa) |
| | TDP1 | Tyrosyl-DNA phosphodiesterase 1. (573 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | TERF2IP | TERF2 interacting protein. (400 aa) |
| | RNF138 | Ring finger protein 138. (216 aa) |
| | WDR48 | WD repeat domain 48. (644 aa) |
| | SHOC1 | Shortage in chiasmata 1. (1381 aa) |
| | ENSRBIP00000019027 | Uncharacterized protein. (312 aa) |
| | RECQL4 | RecQ like helicase 4. (1197 aa) |
| | WBP11 | Uncharacterized protein. (637 aa) |
| | POU4F1 | POU domain protein. (424 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (907 aa) |
| | ENSRBIP00000021679 | Uncharacterized protein. (269 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | YBX1 | CSD_1 domain-containing protein. (282 aa) |
| | RAD51B | RAD51 paralog B. (426 aa) |
| | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (752 aa) |
| | RPA2 | Replication protein A2. (273 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | TDP2 | Tyrosyl-DNA phosphodiesterase 2. (358 aa) |
| | HROB | Chromosome 17 open reading frame 53. (437 aa) |
| | REXO4 | REX4 homolog, 3'-5' exonuclease. (422 aa) |
| | MYEF2 | Myelin expression factor 2. (600 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | LOC108516807 | Uncharacterized protein. (564 aa) |
| | FBH1 | F-box DNA helicase 1. (1079 aa) |
| | CDC45 | Cell division cycle 45. (552 aa) |
| | SWSAP1 | SWIM-type zinc finger 7 associated protein 1. (250 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (421 aa) |
| | PCBP2 | Poly(rC) binding protein 2. (366 aa) |
| | NABP2 | Nucleic acid binding protein 2. (211 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (687 aa) |
| | NUP35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa) |
| | SMC5 | Structural maintenance of chromosomes 5. (1054 aa) |
| | RAD23A | RAD23 homolog A, nucleotide excision repair protein. (363 aa) |
| | ENSRBIP00000031803 | RRM domain-containing protein. (287 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (337 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1243 aa) |
| | SPRTN | SprT-like N-terminal domain. (488 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (998 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (907 aa) |
| | LRPPRC | PPR_long domain-containing protein. (1401 aa) |
| | SMC4 | Structural maintenance of chromosomes protein. (1253 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (793 aa) |
| | HNRNPDL | Heterogeneous nuclear ribonucleoprotein D like. (428 aa) |
| | MEIOB | Meiosis specific with OB-fold. (449 aa) |
| | LOC108529358 | CSD_1 domain-containing protein. (284 aa) |
| | BLM | BLM RecQ like helicase. (1396 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (959 aa) |
| | POT1 | Protection of telomeres 1. (633 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (904 aa) |
| | LONP1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (1019 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | DDX11 | DEAD/H-box helicase 11. (906 aa) |
| | TSN | Translin. (228 aa) |
| | DHX9 | DExH-box helicase 9. (1275 aa) |
| | RAD51AP2 | RAD51 associated protein 2. (1159 aa) |
| | ENSRBIP00000035711 | RAD51_interact domain-containing protein. (282 aa) |
| | FUBP3 | Uncharacterized protein. (572 aa) |
| | NOL12 | Uncharacterized protein. (213 aa) |
| | CTC1 | CST telomere replication complex component 1. (1217 aa) |
| | SSBP3 | Single stranded DNA binding protein 3. (369 aa) |
| | TWNK | Twinkle mtDNA helicase. (684 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (406 aa) |
| | FUBP1 | Far upstream element binding protein 1. (666 aa) |
| | RAD54L | RAD54 like. (747 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (376 aa) |
| | HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (354 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (289 aa) |
| | ENSRBIP00000011440 | HELICc2 domain-containing protein. (117 aa) |
| | SSBP2 | Single stranded DNA binding protein 2. (357 aa) |
| | RAD18 | RAD18 E3 ubiquitin protein ligase. (494 aa) |
| | IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (985 aa) |
| | HSF1 | Heat shock transcription factor 1. (489 aa) |
| | RBMS1 | RNA binding motif single stranded interacting protein 1. (422 aa) |
| | DHX36 | DEAH-box helicase 36. (971 aa) |
| | RAD23B | RAD23 homolog B, nucleotide excision repair protein. (375 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (898 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (766 aa) |
| | SSBP1 | Single stranded DNA binding protein 1. (148 aa) |
| | ENSRBIP00000008618 | Uncharacterized protein. (361 aa) |
| | XPC | XPC complex subunit, DNA damage recognition and repair factor. (939 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (419 aa) |
| | LOC108525285 | Uncharacterized protein. (274 aa) |
