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| | PAXIP1 | PAX interacting protein 1. (1086 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1050 aa) |
| | INO80D | INO80 complex subunit D. (1028 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1418 aa) |
| | ENSRBIP00000043218 | Uncharacterized protein. (153 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (898 aa) |
| | LOC108532656 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (172 aa) |
| | NIPBL | Nipped-B protein. (2777 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (628 aa) |
| | BRCA2 | Uncharacterized protein. (386 aa) |
| | SEM1 | SEM1 26S proteasome complex subunit. (110 aa) |
| | REC8 | REC8 meiotic recombination protein. (545 aa) |
| | ENSRBIP00000000510 | Uncharacterized protein. (105 aa) |
| | EXOSC6 | Exosome component 6. (272 aa) |
| | NSMCE2 | SP-RING-type domain-containing protein. (246 aa) |
| | ENSRBIP00000000804 | RPA_C domain-containing protein. (235 aa) |
| | CCNB1IP1 | RING-type domain-containing protein. (293 aa) |
| | MSH3 | MutS homolog 3. (1195 aa) |
| | DCLRE1C | DNA cross-link repair 1C. (689 aa) |
| | POLN | DNA polymerase nu. (892 aa) |
| | ENSRBIP00000001755 | Uncharacterized protein. (218 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa) |
| | REC114 | REC114 meiotic recombination protein. (182 aa) |
| | RPAIN | RPA interacting protein. (219 aa) |
| | FANCM | FA complementation group M. (2047 aa) |
| | MSH4 | MutS homolog 4. (935 aa) |
| | ENSRBIP00000002911 | Uncharacterized protein. (190 aa) |
| | ENSRBIP00000003311 | Uncharacterized protein. (200 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1367 aa) |
| | ENSRBIP00000003378 | Metallophos domain-containing protein. (233 aa) |
| | ENSRBIP00000003851 | Uncharacterized protein. (199 aa) |
| | NABP1 | Nucleic acid binding protein 1. (204 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1305 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (468 aa) |
| | TPRKB | TP53RK binding protein; Belongs to the CGI121/TPRKB family. (175 aa) |
| | AP5Z1 | Adaptor related protein complex 5 subunit zeta 1. (808 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | FSBP | Uncharacterized protein. (908 aa) |
| | ENSRBIP00000004795 | DUF4502 domain-containing protein. (197 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | CYREN | Cell cycle regulator of NHEJ. (159 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1559 aa) |
| | RNF212B | Ring finger protein 212B. (300 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1226 aa) |
| | HMGB1-2 | Uncharacterized protein. (215 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | FANCD2 | Uncharacterized protein. (1422 aa) |
| | LOC108520651 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | AICDA | Activation induced cytidine deaminase. (199 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | RMI1 | RecQ mediated genome instability 1. (625 aa) |
| | INO80C | INO80 complex subunit C. (228 aa) |
| | MLH1 | MutL homolog 1. (754 aa) |
| | MSH5 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (778 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (419 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | LOC108526191 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa) |
| | PGBD5 | PiggyBac transposable element derived 5. (508 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1515 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1311 aa) |
| | MCRS1 | Microspherule protein 1. (475 aa) |
| | TM4SF19 | Uncharacterized protein. (295 aa) |
| | ENSRBIP00000009081 | Uncharacterized protein. (227 aa) |
| | PALB2 | Partner and localizer of BRCA2. (1149 aa) |
| | TRIP13 | Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (398 aa) |
| | ENSRBIP00000009490 | Uncharacterized protein. (81 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1718 aa) |
| | ENSRBIP00000010048 | YL1_C domain-containing protein. (93 aa) |
| | HDGFL2 | HDGF like 2. (575 aa) |
| | HUS1B | Checkpoint protein; Belongs to the HUS1 family. (277 aa) |
| | KLHDC3 | Kelch domain containing 3. (370 aa) |
| | ENSRBIP00000010478 | SP-RING-type domain-containing protein. (216 aa) |
| | LIG3 | DNA ligase. (950 aa) |
| | TCF7 | Transcription factor 7. (399 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | CENPS-CORT | CENPS-CORT readthrough. (143 aa) |
| | ENSRBIP00000011182 | Ku domain-containing protein. (328 aa) |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2508 aa) |
| | BLM | BLM RecQ like helicase. (1396 aa) |
| | TCF3 | Transcription factor 3. (654 aa) |
| | MEIOB | Meiosis specific with OB-fold. (449 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (303 aa) |
| | HMGB3-2 | Uncharacterized protein. (203 aa) |
| | RHNO1 | Uncharacterized protein. (240 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | ENSRBIP00000013688 | Uncharacterized protein. (232 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | HMGB3 | High mobility group box 3. (187 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) |
| | TEP1 | Telomerase associated protein 1. (2633 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa) |
| | XRCC3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (347 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (907 aa) |
| | MLH3 | MutL homolog 3. (1449 aa) |
| | SUPV3L1 | Suv3 like RNA helicase. (544 aa) |
| | HMGB1 | Uncharacterized protein. (181 aa) |
| | SPO11 | SPO11 initiator of meiotic double stranded breaks. (407 aa) |
| | RAD51C | RAD51 paralog C. (376 aa) |
| | ANKLE1 | Ankyrin repeat and LEM domain containing 1. (669 aa) |
| | WRN | WRN RecQ like helicase. (1394 aa) |
| | INO80 | INO80 complex ATPase subunit. (1555 aa) |
| | EPC1 | Enhancer of polycomb homolog. (836 aa) |
| | MBTD1 | Mbt domain containing 1. (722 aa) |
| | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (232 aa) |
| | SMC6 | Structural maintenance of chromosomes 6. (1040 aa) |
| | RNF212 | Uncharacterized protein. (190 aa) |
| | NSMCE4A | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa) |
| | EME2 | Essential meiotic structure-specific endonuclease subunit 2. (377 aa) |
| | LOC108521278 | Uncharacterized protein. (1136 aa) |
| | C14orf39 | Chromosome 14 open reading frame 39. (569 aa) |
| | AP5S1 | Adaptor related protein complex 5 subunit sigma 1. (250 aa) |
| | ENSRBIP00000017090 | Uncharacterized protein. (120 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (641 aa) |
| | RNF138 | Ring finger protein 138. (216 aa) |
| | WDR48 | WD repeat domain 48. (644 aa) |
| | ENSRBIP00000017801 | Uncharacterized protein. (86 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (805 aa) |
| | KIAA1841 | KIAA1841. (640 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | EME1 | Essential meiotic structure-specific endonuclease 1. (571 aa) |
| | SHOC1 | Shortage in chiasmata 1. (1381 aa) |
| | RECQL4 | RecQ like helicase 4. (1197 aa) |
| | ENSRBIP00000019157 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (78 aa) |
| | SPIDR | DUF4503 domain-containing protein. (397 aa) |
| | ENSRBIP00000019782 | Kin17_mid domain-containing protein. (206 aa) |
| | HFM1 | Helicase ATP-binding domain-containing protein. (471 aa) |
| | ENSRBIP00000019863 | Uncharacterized protein. (57 aa) |
| | FOXP3 | Forkhead box P3. (456 aa) |
| | INIP | INTS3 and NABP interacting protein. (104 aa) |
| | FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1017 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (908 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3026 aa) |
| | ENSRBIP00000020385 | Uncharacterized protein. (199 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (907 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa) |
| | ENSRBIP00000021707 | Uncharacterized protein. (240 aa) |
| | POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa) |
| | INTS3 | Integrator complex subunit 3. (976 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (576 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | SFPQ | Splicing factor proline and glutamine rich. (640 aa) |
| | SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (377 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (670 aa) |
| | PSMC3IP | PSMC3 interacting protein. (217 aa) |
| | HDAC10 | Histone deacetylase 10. (673 aa) |
| | ENSRBIP00000022903 | Uncharacterized protein. (60 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa) |
| | CENPX | Centromere protein X. (133 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | XRCC4 | X-ray repair cross complementing 4. (231 aa) |
| | C11orf80 | Chromosome 11 open reading frame 80. (511 aa) |
| | LOC108525622 | Uncharacterized protein. (425 aa) |
| | RAD51B | RAD51 paralog B. (426 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (309 aa) |
| | RPA2 | Replication protein A2. (273 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (864 aa) |
| | APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (518 aa) |
| | MND1 | Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (190 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | EXO1 | Exonuclease 1. (827 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (752 aa) |
| | INO80E | INO80 complex subunit E. (244 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1475 aa) |
| | HROB | Chromosome 17 open reading frame 53. (437 aa) |
| | RFWD3 | Ring finger and WD repeat domain 3. (773 aa) |
| | ENSRBIP00000026978 | Uncharacterized protein. (179 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | RMI2 | RecQ mediated genome instability 2. (150 aa) |
| | NONO | Non-POU domain containing octamer binding. (366 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | FBH1 | F-box DNA helicase 1. (1079 aa) |
| | CDC45 | Cell division cycle 45. (552 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (322 aa) |
| | SWSAP1 | SWIM-type zinc finger 7 associated protein 1. (250 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1343 aa) |
| | ANKRD31 | RAMA domain-containing protein. (622 aa) |
| | HSF2BP | Heat shock transcription factor 2 binding protein. (294 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | CCDC36 | Coiled-coil domain containing 36. (599 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1712 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa) |
| | RAD21 | RAD21 cohesin complex component. (584 aa) |
| | NABP2 | Nucleic acid binding protein 2. (211 aa) |
| | SYCE3 | Synaptonemal complex central element protein 3. (88 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (281 aa) |
| | SMC5 | Structural maintenance of chromosomes 5. (1054 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (337 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1243 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (568 aa) |
| | FANCB | FA complementation group B. (516 aa) |
| | LIG4 | DNA ligase. (901 aa) |
| | ENSRBIP00000032381 | Uncharacterized protein. (130 aa) |
| | SLX4 | SLX4 structure-specific endonuclease subunit. (1814 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (345 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | MEI4 | Meiotic double-stranded break formation protein 4. (290 aa) |
| | SEM1-2 | Uncharacterized protein. (89 aa) |
| | SYCP1 | Synaptonemal complex protein 1. (927 aa) |
| | SETX | Senataxin. (2655 aa) |
| | CDC7 | Cell division cycle 7. (574 aa) |
| | ENSRBIP00000033932 | LEDGF domain-containing protein. (228 aa) |
| | ENSRBIP00000033992 | Uncharacterized protein. (157 aa) |
| | MUS81 | MUS81 structure-specific endonuclease subunit. (551 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3106 aa) |
| | ZSWIM7 | Zinc finger SWIM-type containing 7. (132 aa) |
| | RAD51AP2 | RAD51 associated protein 2. (1159 aa) |
| | ENSRBIP00000035711 | RAD51_interact domain-containing protein. (282 aa) |
| | HELQ | Helicase, POLQ like. (1101 aa) |
| | PAGR1 | PAXIP1 associated glutamate rich protein 1. (254 aa) |
| | ACTR5 | Actin related protein 5; Belongs to the actin family. (607 aa) |
| | ENSRBIP00000036862 | Ku domain-containing protein. (567 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa) |
| | ENSRBIP00000037559 | Uncharacterized protein. (198 aa) |
| | CCDC155 | Coiled-coil domain containing 155. (562 aa) |
| | AUNIP | Aurora kinase A and ninein interacting protein. (351 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
| | CNTD1 | Cyclin N-terminal domain containing 1. (330 aa) |
| | EID3 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (426 aa) |
| | RAD54L | RAD54 like. (747 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (631 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (771 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (376 aa) |
| | C1orf146 | Chromosome 1 open reading frame 146. (180 aa) |
| | LIG1 | DNA ligase. (928 aa) |
| | ENSRBIP00000040579 | Sld5 domain-containing protein. (151 aa) |
| | SFR1 | SWI5 dependent homologous recombination repair protein 1. (245 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (289 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | KIN | Kin17_mid domain-containing protein. (393 aa) |
| | ENSRBIP00000041364 | Ku domain-containing protein. (498 aa) |
