STRINGSTRING
TEP1 TEP1 ERCC1 ERCC1 DMC1 DMC1 RAD51 RAD51 SMC5 SMC5 XRCC4 XRCC4 GEN1 GEN1 SMC6 SMC6 RAD51C RAD51C ERCC4 ERCC4 XRCC3 XRCC3 MSH2 MSH2 ENSRBIP00000010478 ENSRBIP00000010478 RAD52 RAD52 FSBP FSBP TPRKB TPRKB MSH3 MSH3 NSMCE2 NSMCE2 BRCA2 BRCA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEP1Telomerase associated protein 1. (2633 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (289 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (376 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (337 aa)
SMC5Structural maintenance of chromosomes 5. (1054 aa)
XRCC4X-ray repair cross complementing 4. (231 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (908 aa)
SMC6Structural maintenance of chromosomes 6. (1040 aa)
RAD51CRAD51 paralog C. (376 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (907 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (347 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
ENSRBIP00000010478SP-RING-type domain-containing protein. (216 aa)
RAD52RAD52 homolog, DNA repair protein. (419 aa)
FSBPUncharacterized protein. (908 aa)
TPRKBTP53RK binding protein; Belongs to the CGI121/TPRKB family. (175 aa)
MSH3MutS homolog 3. (1195 aa)
NSMCE2SP-RING-type domain-containing protein. (246 aa)
BRCA2Uncharacterized protein. (386 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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