129 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPR157	G protein-coupled receptor 157. (335 aa)
	ADGRG2	Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. (892 aa)
	ADRB2	Adrenoceptor beta 2. (399 aa)
	PTGER2	Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	LOC108541626	Uncharacterized protein. (246 aa)
	ADM	Adrenomedullin. (185 aa)
	GIPR	Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
	PDE4D	Phosphodiesterase. (809 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1531 aa)
	ADRA1A	Adrenoceptor alpha 1A. (455 aa)
	CNR1	Uncharacterized protein. (36 aa)
	GHRH	Growth hormone releasing hormone. (107 aa)
	ADGRE2	Adhesion G protein-coupled receptor E2; Belongs to the G-protein coupled receptor 2 family. (847 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (882 aa)
	ADGRF1	Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (908 aa)
	GNAQ	G protein subunit alpha q. (359 aa)
	GNAS	GNAS complex locus. (1041 aa)
	ADRA2A	Adrenoceptor alpha 2A. (400 aa)
	GNAL	G protein subunit alpha L. (448 aa)
	LOC108513979	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (266 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	CRHR1	Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
	GPHB5	Glycoprotein hormone subunit beta 5. (130 aa)
	ADORA2B	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (394 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
	RXFP2	Relaxin family peptide receptor 2. (724 aa)
	MC1R	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (304 aa)
	RAMP2	Receptor activity modifying protein 2. (175 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1343 aa)
	CALCA	Calcitonin related polypeptide alpha. (144 aa)
	ENSRBIP00000033334	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (676 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	GIP	Gastric inhibitory polypeptide. (151 aa)
	PTGIR	Prostaglandin I2 receptor. (373 aa)
	ADGRE3	Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (599 aa)
	PTGER1	Prostaglandin E receptor 1. (227 aa)
	GPR78	G protein-coupled receptor 78. (363 aa)
	ADGRB1	Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1548 aa)
	AKAP13	A-kinase anchoring protein 13. (2816 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (496 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (345 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	VIP	Vasoactive intestinal peptide. (167 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)
	ADGRG7	Adhesion G protein-coupled receptor G7; Belongs to the G-protein coupled receptor 2 family. (796 aa)
	ADGRF4	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (751 aa)
	ADGRD1	Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (770 aa)
	CALCRL	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
	CALCB	Calcitonin related polypeptide beta. (138 aa)
	ADGRG6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1248 aa)
	GCG	Glucagon. (180 aa)
	ENSRBIP00000026977	Latrophilin domain-containing protein. (173 aa)
	ENSRBIP00000025347	SCY domain-containing protein. (90 aa)
	TBXA2R	Thromboxane A2 receptor. (379 aa)
	ADORA2A	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	ENSRBIP00000024009	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	ADCY8	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
	TUBB3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (773 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2261 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
	PTGER3	Prostaglandin E receptor 3. (418 aa)
	ADGRF3	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family. (1068 aa)
	PF4	C-X-C motif chemokine. (101 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
	ADGRL3	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1104 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
	CXCL11	C-X-C motif chemokine. (94 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	CHGA	Chromogranin A. (510 aa)
	ADM5	Adrenomedullin 5 (putative). (128 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (176 aa)
	RAMP3	Receptor activity modifying protein 3. (151 aa)
	ADRB1	Adrenoceptor beta 1; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	GALR2	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
	ADM2	Adrenomedullin 2. (148 aa)
	GPR161	G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (592 aa)
	PTH1R	Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (593 aa)
	ADGRL4	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (677 aa)
	GCGR	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (522 aa)
	GPR4	G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	TMEM116	Transmembrane protein 116. (332 aa)
	PTRHD1	Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
	GPHA2	Glycoprotein hormone subunit alpha 2. (127 aa)
	GPER1	G protein-coupled estrogen receptor 1. (373 aa)
	ADGRE1	Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (727 aa)
	RIT2	Ras like without CAAX 2. (217 aa)
	MC4R	Melanocortin 4 receptor. (332 aa)
	ADGRG1	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (692 aa)
	ADGRG4	Adhesion G protein-coupled receptor G4; Belongs to the G-protein coupled receptor 2 family. (3051 aa)
	ADGRG5	Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family. (533 aa)
	LPAR3	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (341 aa)
	CNR2	Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	ADRA2B	Adrenoceptor alpha 2B. (451 aa)
	ADRA1B	Adrenoceptor alpha 1B. (500 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (645 aa)
	ADRA1D	Adrenoceptor alpha 1D. (491 aa)
	GNA13	G protein subunit alpha 13. (353 aa)
	ADGRG3	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (551 aa)
	CXCL9	C-X-C motif chemokine ligand 9. (125 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	CHRM1	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
	PLN	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
	GALR1	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (348 aa)
	IAPP	Islet amyloid polypeptide. (86 aa)
	ADGRE5	Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (779 aa)
	RAMP1	Receptor activity modifying protein 1. (140 aa)
	TCP11	T-complex 11. (516 aa)
	PTHLH	Parathyroid hormone like hormone. (209 aa)
	ADRB3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
	S1PR2	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
	LOC108523468	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1474 aa)
	S1PR3	Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	GPR26	G protein-coupled receptor 26. (337 aa)
	GPR3	G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)
	S1PR1	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	PTGFR	Prostaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	LOC108523462	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	ADGRD2	Adhesion G protein-coupled receptor D2; Belongs to the G-protein coupled receptor 2 family. (978 aa)
	ADGRL2	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1482 aa)
	GPR119	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
	GPR12	G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	MC3R	Melanocortin 3 receptor. (323 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSRBIP00000035296	ENSRBIP00000024365	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY1	ADCY3	ENSRBIP00000035296	ENSRBIP00000021747	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.944
ADCY1	ADCY4	ENSRBIP00000035296	ENSRBIP00000022756	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.446
ADCY1	ADCY5	ENSRBIP00000035296	ENSRBIP00000034265	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY6	ENSRBIP00000035296	ENSRBIP00000004607	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.429
ADCY1	ADCY7	ENSRBIP00000035296	ENSRBIP00000016019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.488
ADCY1	ADCY8	ENSRBIP00000035296	ENSRBIP00000023627	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.957
ADCY1	ADCY9	ENSRBIP00000035296	ENSRBIP00000021122	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.672
ADCY1	ADRA2A	ENSRBIP00000035296	ENSRBIP00000036669	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adrenoceptor alpha 2A.	0.492
ADCY1	ADRA2B	ENSRBIP00000035296	ENSRBIP00000010683	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adrenoceptor alpha 2B.	0.541
ADCY1	CNR1	ENSRBIP00000035296	ENSRBIP00000040532	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.912
ADCY1	GNAL	ENSRBIP00000035296	ENSRBIP00000036655	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.674
ADCY1	GNAS	ENSRBIP00000035296	ENSRBIP00000036792	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.970
ADCY1	GNG2	ENSRBIP00000035296	ENSRBIP00000022343	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.827
ADCY1	LOC108541626	ENSRBIP00000035296	ENSRBIP00000041615	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.903
ADCY1	PDE4D	ENSRBIP00000035296	ENSRBIP00000041082	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.722
ADCY1	PTRHD1	ENSRBIP00000035296	ENSRBIP00000016259	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Peptidyl-tRNA hydrolase domain containing 1.	0.465
ADCY1	RAPGEF4	ENSRBIP00000035296	ENSRBIP00000038017	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Rap guanine nucleotide exchange factor 4.	0.917
ADCY2	ADCY1	ENSRBIP00000024365	ENSRBIP00000035296	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.458
ADCY2	ADCY4	ENSRBIP00000024365	ENSRBIP00000022756	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.415