66 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108535070	Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. (350 aa)
	REL	REL proto-oncogene, NF-kB subunit. (602 aa)
	DEFB124	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (71 aa)
	TIFA	TRAF interacting protein with forkhead associated domain. (185 aa)
	RIPK3	Receptor interacting serine/threonine kinase 3. (518 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1153 aa)
	FAIM	Fas apoptotic inhibitory molecule. (212 aa)
	BIRC3	Baculoviral IAP repeat containing 3. (604 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	CARD11	Caspase recruitment domain family member 11. (1154 aa)
	IKBKE	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
	ENSRBIP00000006958	TNF receptor-associated factor. (473 aa)
	NKIRAS1	NFKB inhibitor interacting Ras like 1. (192 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	CARD9	Caspase recruitment domain family member 9. (536 aa)
	ROCK1	Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
	AKT1	AKT serine/threonine kinase 1. (486 aa)
	BIRC2	Baculoviral IAP repeat containing 2. (618 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (426 aa)
	ATP6V1G2	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
	DAB2IP	DAB2 interacting protein. (1156 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
	AVPR2	Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa)
	RELA	Uncharacterized protein. (282 aa)
	TIRAP	TIR domain containing adaptor protein. (233 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (507 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	TLR8	Toll like receptor 8; Belongs to the Toll-like receptor family. (1016 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (947 aa)
	TICAM1	Toll like receptor adaptor molecule 1. (515 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	AZI2	5-azacytidine induced 2. (392 aa)
	TANK	TRAF family member associated NFKB activator. (425 aa)
	ZNF675	Zinc finger protein 675. (530 aa)
	EDN1	Endothelin 1. (211 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
	TLR9	TIR domain-containing protein. (1033 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (537 aa)
	TBK1	TANK binding kinase 1. (681 aa)
	BCL3	BCL3 transcription coactivator. (405 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (541 aa)
	NFKBIL1	NFKB inhibitor like 1. (381 aa)
	ASH1L	ASH1 like histone lysine methyltransferase. (2894 aa)
	AJUBA	Ajuba LIM protein. (538 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	NKIRAS2	NFKB inhibitor interacting Ras like 2. (231 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
	NLRC3	NLR family CARD domain containing 3. (1091 aa)
	LOC108521073	Uncharacterized protein. (133 aa)
	SNIP1	Smad nuclear interacting protein 1. (396 aa)
	ENSRBIP00000038500	RHD domain-containing protein. (112 aa)
	PRDX4	Peroxiredoxin 4. (232 aa)
	TBKBP1	TBK1 binding protein 1. (614 aa)
	NFKBIA	NFKB inhibitor alpha. (317 aa)
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (809 aa)
	BCL10	BCL10 immune signaling adaptor. (233 aa)
	BTK	Tyrosine-protein kinase. (673 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	BIRC2	ENSRBIP00000007933	ENSRBIP00000011618	Tyrosine-protein kinase.	Baculoviral IAP repeat containing 2.	0.412
ABL1	BIRC3	ENSRBIP00000007933	ENSRBIP00000003782	Tyrosine-protein kinase.	Baculoviral IAP repeat containing 3.	0.412
ABL1	CTNNB1	ENSRBIP00000007933	ENSRBIP00000022705	Tyrosine-protein kinase.	Catenin beta 1.	0.694
AKT1	BCL10	ENSRBIP00000010710	ENSRBIP00000041432	AKT serine/threonine kinase 1.	BCL10 immune signaling adaptor.	0.406
AKT1	BTK	ENSRBIP00000010710	ENSRBIP00000042366	AKT serine/threonine kinase 1.	Tyrosine-protein kinase.	0.516
AKT1	CHUK	ENSRBIP00000010710	ENSRBIP00000023948	AKT serine/threonine kinase 1.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.907
AKT1	CTNNB1	ENSRBIP00000010710	ENSRBIP00000022705	AKT serine/threonine kinase 1.	Catenin beta 1.	0.782
AKT1	ENSRBIP00000006958	ENSRBIP00000010710	ENSRBIP00000006958	AKT serine/threonine kinase 1.	TNF receptor-associated factor.	0.603
AKT1	ENSRBIP00000038500	ENSRBIP00000010710	ENSRBIP00000038500	AKT serine/threonine kinase 1.	RHD domain-containing protein.	0.432
AKT1	FYN	ENSRBIP00000010710	ENSRBIP00000006312	AKT serine/threonine kinase 1.	Tyrosine-protein kinase.	0.633
AKT1	IKBKB	ENSRBIP00000010710	ENSRBIP00000027811	AKT serine/threonine kinase 1.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.766
AKT1	IKBKE	ENSRBIP00000010710	ENSRBIP00000004507	AKT serine/threonine kinase 1.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.485
AKT1	IKBKG	ENSRBIP00000010710	ENSRBIP00000015173	AKT serine/threonine kinase 1.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.445
AKT1	MYD88	ENSRBIP00000010710	ENSRBIP00000010319	AKT serine/threonine kinase 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.520
AKT1	NFKBIA	ENSRBIP00000010710	ENSRBIP00000039262	AKT serine/threonine kinase 1.	NFKB inhibitor alpha.	0.456
AKT1	RELA	ENSRBIP00000010710	ENSRBIP00000018109	AKT serine/threonine kinase 1.	Uncharacterized protein.	0.432
AKT1	TBK1	ENSRBIP00000010710	ENSRBIP00000030823	AKT serine/threonine kinase 1.	TANK binding kinase 1.	0.661
AKT1	TLR4	ENSRBIP00000010710	ENSRBIP00000006333	AKT serine/threonine kinase 1.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.480
AKT1	TRAF6	ENSRBIP00000010710	ENSRBIP00000036224	AKT serine/threonine kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.603
ASH1L	MYD88	ENSRBIP00000031348	ENSRBIP00000010319	ASH1 like histone lysine methyltransferase.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.453