STRINGSTRING
FGF14 FGF14 MAPK8IP2 MAPK8IP2 MYD88 MYD88 ENSRBIP00000010265 ENSRBIP00000010265 CARD9 CARD9 TLR3 TLR3 CDC42EP5 CDC42EP5 MAPK9 MAPK9 CASR CASR SMAD3 SMAD3 TLR4 TLR4 MAP3K7 MAP3K7 GPS2 GPS2 TLR7 TLR7 GPS1 GPS1 RIPK2 RIPK2 ARHGEF6 ARHGEF6 MAPK10 MAPK10 NOD2 NOD2 NOX1 NOX1 STRADB STRADB MAP2K4 MAP2K4 MAP3K5 MAP3K5 CRKL CRKL IRAK1 IRAK1 TRIB1 TRIB1 TNFSF11 TNFSF11 ERCC6 ERCC6 STK3 STK3 ENSRBIP00000022247 ENSRBIP00000022247 MAP3K10 MAP3K10 MAP4K3 MAP4K3 SH2D3A SH2D3A MAP3K20 MAP3K20 ENSRBIP00000016494 ENSRBIP00000016494 SH2D3C SH2D3C DUSP9 DUSP9 LOC108539701 LOC108539701 MAP3K13 MAP3K13 DAXX DAXX MAPK8 MAPK8 NOD1 NOD1 TNFRSF19 TNFRSF19 MAP4K1 MAP4K1 MAP3K11 MAP3K11 ATF2 ATF2 MAP2K7 MAP2K7 FGF12 FGF12 MAP4K2 MAP4K2 IRAK4 IRAK4 ENSRBIP00000039740 ENSRBIP00000039740 MINK1 MINK1 WNT5A WNT5A MAPK8IP1 MAPK8IP1 LRRK2 LRRK2 MAP3K12 MAP3K12 NFKB1 NFKB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (769 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
ENSRBIP00000010265Uncharacterized protein. (161 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
CDC42EP5CDC42 effector protein 5. (148 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
CASRCalcium sensing receptor. (1078 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
GPS2G protein pathway suppressor 2. (327 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
GPS1G protein pathway suppressor 1. (527 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
ARHGEF6DH domain-containing protein. (402 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
NOX1NADPH oxidase 1. (532 aa)
STRADBSTE20 related adaptor beta. (376 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (408 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (702 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1484 aa)
STK3Serine/threonine kinase 3. (490 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
MAP3K10Uncharacterized protein; Belongs to the protein kinase superfamily. (289 aa)
MAP4K3Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (813 aa)
SH2D3ASH2 domain containing 3A. (574 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
ENSRBIP00000016494Protein kinase domain-containing protein. (253 aa)
SH2D3CSH2 domain containing 3C. (860 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
LOC108539701Uncharacterized protein. (833 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
DAXXDeath domain associated protein. (740 aa)
MAPK8Mitogen-activated protein kinase 8. (383 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
TNFRSF19TNF receptor superfamily member 19. (416 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (819 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (429 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (414 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (854 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (461 aa)
ENSRBIP00000039740Protein kinase domain-containing protein. (374 aa)
MINK1Misshapen like kinase 1. (1332 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (704 aa)
LRRK2Protein kinase domain-containing protein. (537 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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