STRINGSTRING
TSPAN32 TSPAN32 F13A1 F13A1 MERTK MERTK DGKG DGKG GNA12 GNA12 PROZ PROZ GP1BA GP1BA F2 F2 STXBP3 STXBP3 SERPINC1 SERPINC1 APOH APOH FGB FGB PF4 PF4 CD40LG CD40LG SYK SYK PF4V1 PF4V1 PPIA PPIA GP6 GP6 C4BPB C4BPB ADORA2A ADORA2A HNF4A HNF4A LOC108540315 LOC108540315 TFPI TFPI PLEK PLEK ENSRBIP00000025670 ENSRBIP00000025670 GNAS GNAS F2R F2R LOC108521383 LOC108521383 DGKA DGKA MPL MPL CTSG CTSG ENPP4 ENPP4 ANO6 ANO6 VWF VWF VKORC1 VKORC1 VAV3 VAV3 GNAQ GNAQ RAB27A RAB27A CLIC1 CLIC1 MYH9 MYH9 PLG PLG PAPSS2 PAPSS2 SERPINA10 SERPINA10 PAFAH2 PAFAH2 PTPN6 PTPN6 PEAR1 PEAR1 DGKB DGKB SLC7A11 SLC7A11 PIK3CG PIK3CG FBLN1 FBLN1 FGA FGA DGKZ DGKZ TLN1 TLN1 LOC108541626 LOC108541626 DGKI DGKI LMAN1 LMAN1 TREML1 TREML1 FZD6 FZD6 WAS WAS ENSRBIP00000043641 ENSRBIP00000043641 F8 F8 DGKQ DGKQ TFPI2 TFPI2 PROCR PROCR ENSRBIP00000029649 ENSRBIP00000029649 ENSRBIP00000030150 ENSRBIP00000030150 DTNBP1 DTNBP1 SRF SRF MMRN1 MMRN1 HRG HRG FN1 FN1 RAP2B RAP2B COMP COMP VAV2 VAV2 ENSRBIP00000001876 ENSRBIP00000001876 BLOC1S3 BLOC1S3 SRC SRC GP9 GP9 F3 F3 DGKK DGKK AP3B1 AP3B1 PLSCR1 PLSCR1 ENTPD1 ENTPD1 P2RX1 P2RX1 SCUBE1 SCUBE1 UBASH3B UBASH3B F2RL2 F2RL2 HPS6 HPS6 SERPIND1 SERPIND1 LOC108534255 LOC108534255 JMJD1C JMJD1C GAS6 GAS6 HGFAC HGFAC P2RY1 P2RY1 GATA1 GATA1 KNG1 KNG1 PROS1 PROS1 SERPINE2 SERPINE2 VCL VCL ITGB3 ITGB3 MYL9 MYL9 COL3A1 COL3A1 GP1BB GP1BB F12 F12 DGKD DGKD SERPING1 SERPING1 GNA13 GNA13 TYRO3 TYRO3 CD36 CD36 ADRA2B ADRA2B SHH SHH FIBP FIBP BLOC1S4 BLOC1S4 F5 F5 FERMT3 FERMT3 HSPB1 HSPB1 PIK3CB PIK3CB PABPC4L PABPC4L DGKH DGKH BLOC1S6 BLOC1S6 PLCG2 PLCG2 ENSRBIP00000013453 ENSRBIP00000013453 F10 F10 HPS5 HPS5 F7 F7 ENSRBIP00000030321 ENSRBIP00000030321 ITPK1 ITPK1 LCK LCK PABPC4 PABPC4 WNT3A WNT3A ENSRBIP00000032230 ENSRBIP00000032230 LOC108516810 LOC108516810 DGKE DGKE ADAMTS13 ADAMTS13 VAV1 VAV1 PROC PROC PRSS56 PRSS56 CD9 CD9 FGG FGG ITGA2 ITGA2 ANXA5 ANXA5 MPIG6B MPIG6B ENSRBIP00000036194 ENSRBIP00000036194 ADRA2A ADRA2A AXL AXL CSRP1 CSRP1 F13B F13B P2RY12 P2RY12 C1GALT1C1 C1GALT1C1 CPB2 CPB2 ENTPD2 ENTPD2 F11 F11 PIK3CA PIK3CA HPS4 HPS4 SLC4A1 SLC4A1 ENSRBIP00000018465 ENSRBIP00000018465
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (369 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
MERTKMER proto-oncogene, tyrosine kinase. (997 aa)
DGKGDiacylglycerol kinase. (791 aa)
GNA12G protein subunit alpha 12. (322 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (599 aa)
F2Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (572 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (548 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (464 aa)
APOHApolipoprotein H. (289 aa)
FGBFibrinogen beta chain. (491 aa)
PF4C-X-C motif chemokine. (101 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
SYKUncharacterized protein. (331 aa)
PF4V1C-X-C motif chemokine. (101 aa)
PPIAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
GP6Uncharacterized protein. (239 aa)
C4BPBComplement component 4 binding protein beta. (252 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
LOC108540315Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (233 aa)
TFPITissue factor pathway inhibitor. (208 aa)
PLEKPleckstrin. (350 aa)
ENSRBIP00000025670Uncharacterized protein. (68 aa)
GNASGNAS complex locus. (1041 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
LOC108521383Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (242 aa)
DGKADiacylglycerol kinase. (749 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (452 aa)
ANO6Anoctamin. (594 aa)
VWFVon Willebrand factor. (2813 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (164 aa)
VAV3Uncharacterized protein. (287 aa)
GNAQG protein subunit alpha q. (359 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (640 aa)
SERPINA10Serpin family A member 10; Belongs to the serpin family. (477 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (368 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1037 aa)
DGKBDiacylglycerol kinase. (804 aa)
SLC7A11Solute carrier family 7 member 11. (501 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (716 aa)
FGAFibrinogen alpha chain. (906 aa)
DGKZDiacylglycerol kinase. (1102 aa)
TLN1Talin 1. (2562 aa)
LOC108541626Uncharacterized protein. (246 aa)
DGKIDiacylglycerol kinase. (944 aa)
LMAN1Lectin, mannose binding 1. (516 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (311 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
WASWASP actin nucleation promoting factor. (455 aa)
ENSRBIP00000043641Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (154 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (1682 aa)
DGKQDiacylglycerol kinase. (849 aa)
TFPI2Tissue factor pathway inhibitor. (235 aa)
PROCRProtein C receptor. (238 aa)
ENSRBIP00000029649DH domain-containing protein. (251 aa)
ENSRBIP00000030150PPIase cyclophilin-type domain-containing protein. (128 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
SRFSerum response factor. (508 aa)
MMRN1Multimerin 1. (1230 aa)
HRGHistidine rich glycoprotein. (530 aa)
FN1Fibronectin 1. (2477 aa)
RAP2BUncharacterized protein. (183 aa)
COMPCartilage oligomeric matrix protein. (649 aa)
VAV2Vav guanine nucleotide exchange factor 2. (783 aa)
ENSRBIP00000001876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa)
SRCTyrosine-protein kinase. (627 aa)
GP9Glycoprotein IX platelet. (177 aa)
F3Coagulation factor III, tissue factor. (296 aa)
DGKKDiacylglycerol kinase. (1235 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1067 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (326 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (522 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (442 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (1027 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (595 aa)
F2RL2Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
HPS6Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (775 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
LOC108534255G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (443 aa)
JMJD1CJumonji domain containing 1C. (2539 aa)
GAS6Growth arrest specific 6. (623 aa)
HGFACHGF activator; Belongs to the peptidase S1 family. (647 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GATA1GATA binding protein 1. (421 aa)
KNG1Kininogen 1. (644 aa)
PROS1Protein S. (676 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
VCLVinculin. (1118 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
MYL9Myosin light chain 9. (172 aa)
COL3A1Collagen type III alpha 1 chain. (1333 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
F12Coagulation factor XII. (615 aa)
DGKDDiacylglycerol kinase. (1216 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (500 aa)
GNA13G protein subunit alpha 13. (353 aa)
TYRO3TYRO3 protein tyrosine kinase. (893 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ADRA2BAdrenoceptor alpha 2B. (451 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
FIBPFGF1 intracellular binding protein. (357 aa)
BLOC1S4Biogenesis of lysosomal organelles complex 1 subunit 4. (217 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2195 aa)
FERMT3Fermitin family member 3. (663 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (929 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
DGKHDiacylglycerol kinase. (1220 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (176 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ENSRBIP00000013453SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa)
F10Coagulation factor X. (434 aa)
HPS5Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1129 aa)
F7Coagulation factor VII. (461 aa)
ENSRBIP00000030321Uncharacterized protein. (819 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (414 aa)
LCKTyrosine-protein kinase. (518 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ENSRBIP00000032230Uncharacterized protein. (311 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
DGKEDiacylglycerol kinase. (566 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1420 aa)
VAV1Vav guanine nucleotide exchange factor 1. (843 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. (476 aa)
PRSS56Serine protease 56; Belongs to the peptidase S1 family. (603 aa)
CD9Tetraspanin. (278 aa)
FGGFibrinogen gamma chain. (453 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ANXA5Annexin. (320 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (237 aa)
ENSRBIP00000036194Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (156 aa)
ADRA2AAdrenoceptor alpha 2A. (400 aa)
AXLAXL receptor tyrosine kinase. (892 aa)
CSRP1Cysteine and glycine rich protein 1. (193 aa)
F13BCoagulation factor XIII B chain. (661 aa)
P2RY12Purinergic receptor P2Y12. (354 aa)
C1GALT1C1C1GALT1 specific chaperone 1. (301 aa)
CPB2Carboxypeptidase B2. (345 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (625 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (708 aa)
SLC4A1Anion exchange protein. (959 aa)
ENSRBIP00000018465G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (380 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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