STRINGSTRING
CPT1A CPT1A CARTPT CARTPT GCG GCG CCK CCK NEGR1 NEGR1 GHRL GHRL GDF15 GDF15 GALR3 GALR3 LOC108515307 LOC108515307 HELT HELT PRLH PRLH DACH1 DACH1 ENSRBIP00000032944 ENSRBIP00000032944 CALCA CALCA BBIP1 BBIP1 DERL2 DERL2 NTRK2 NTRK2 APP APP NPY1R NPY1R BSX BSX GAL GAL GPR83 GPR83 LEP LEP DMBX1 DMBX1 OPRD1 OPRD1 HCRT HCRT AGRP AGRP STRA6 STRA6 TACR1 TACR1 SLC24A4 SLC24A4 CNTFR CNTFR FOS FOS TBR1 TBR1 ADORA2A ADORA2A ACE2 ACE2 REN REN NMUR2 NMUR2 ENSRBIP00000022449 ENSRBIP00000022449 DACH1-2 DACH1-2 CNTN2 CNTN2 TRH TRH POU4F1 POU4F1 TH TH PMCH PMCH GALR2 GALR2 ADM2 ADM2 OXT OXT HCRTR2 HCRTR2 BBS12 BBS12 APLN APLN ENSRBIP00000011405 ENSRBIP00000011405 PYY PYY GIGYF2 GIGYF2 MRAP2 MRAP2 UBR3 UBR3 HCRTR1 HCRTR1 PPY PPY GHSR GHSR HAND2 HAND2 UBE2Q1 UBE2Q1 PRLHR PRLHR GLS GLS NPW NPW STAT3 STAT3 EN1 EN1 DRD2 DRD2 IAPP IAPP RMI1 RMI1 FYN FYN P2RY1 P2RY1 GFRAL GFRAL ENSRBIP00000004526 ENSRBIP00000004526 PEX13 PEX13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (762 aa)
CARTPTCART prepropeptide. (116 aa)
GCGGlucagon. (180 aa)
CCKCholecystokinin. (115 aa)
NEGR1Neuronal growth regulator 1. (354 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
GDF15Growth differentiation factor 15. (308 aa)
GALR3Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (228 aa)
LOC108515307Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (526 aa)
HELTHelt bHLH transcription factor. (327 aa)
PRLHProlactin releasing hormone. (87 aa)
DACH1Dachshund family transcription factor 1. (477 aa)
ENSRBIP00000032944Uncharacterized protein. (131 aa)
CALCACalcitonin related polypeptide alpha. (144 aa)
BBIP1Uncharacterized protein. (70 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
APPAmyloid beta precursor protein. (770 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
BSXBrain specific homeobox. (232 aa)
GALGalanin and GMAP prepropeptide. (112 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (423 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
DMBX1Diencephalon/mesencephalon homeobox 1. (377 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
AGRPAgouti related neuropeptide. (132 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
CNTFRCiliary neurotrophic factor receptor. (391 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TBR1T-box brain transcription factor 1. (682 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
ACE2Angiotensin-converting enzyme. (769 aa)
RENRenin; Belongs to the peptidase A1 family. (433 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (388 aa)
ENSRBIP00000022449Uncharacterized protein. (254 aa)
DACH1-2Ski_Sno domain-containing protein. (323 aa)
CNTN2Contactin 2. (1040 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
POU4F1POU domain protein. (424 aa)
THTyrosine hydroxylase. (532 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
ADM2Adrenomedullin 2. (148 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (153 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
BBS12Bardet-Biedl syndrome 12. (710 aa)
APLNApelin. (77 aa)
ENSRBIP00000011405G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
PYYPeptide YY. (97 aa)
GIGYF2GRB10 interacting GYF protein 2. (1276 aa)
MRAP2Melanocortin 2 receptor accessory protein 2. (205 aa)
UBR3E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1884 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
PPYPancreatic polypeptide; Belongs to the NPY family. (105 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
UBE2Q1Ubiquitin conjugating enzyme E2 Q1. (411 aa)
PRLHRProlactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa)
GLSGlutaminase. (669 aa)
NPWUncharacterized protein. (350 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
EN1Homeobox protein engrailed-like. (374 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
IAPPIslet amyloid polypeptide. (86 aa)
RMI1RecQ mediated genome instability 1. (625 aa)
FYNTyrosine-protein kinase. (537 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GFRALGDNF family receptor alpha like. (392 aa)
ENSRBIP00000004526Uncharacterized protein. (75 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.