node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGRP | CARTPT | ENSRBIP00000043669 | ENSRBIP00000001289 | Agouti related neuropeptide. | CART prepropeptide. | 0.564 |
AGRP | GHRL | ENSRBIP00000043669 | ENSRBIP00000029484 | Agouti related neuropeptide. | Ghrelin and obestatin prepropeptide. | 0.704 |
AGRP | GHSR | ENSRBIP00000043669 | ENSRBIP00000009607 | Agouti related neuropeptide. | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | 0.566 |
AGRP | LEP | ENSRBIP00000043669 | ENSRBIP00000041070 | Agouti related neuropeptide. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.675 |
CARTPT | AGRP | ENSRBIP00000001289 | ENSRBIP00000043669 | CART prepropeptide. | Agouti related neuropeptide. | 0.564 |
CARTPT | LEP | ENSRBIP00000001289 | ENSRBIP00000041070 | CART prepropeptide. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.499 |
GHRL | AGRP | ENSRBIP00000029484 | ENSRBIP00000043669 | Ghrelin and obestatin prepropeptide. | Agouti related neuropeptide. | 0.704 |
GHRL | GHSR | ENSRBIP00000029484 | ENSRBIP00000009607 | Ghrelin and obestatin prepropeptide. | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | 0.998 |
GHRL | LEP | ENSRBIP00000029484 | ENSRBIP00000041070 | Ghrelin and obestatin prepropeptide. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.892 |
GHSR | AGRP | ENSRBIP00000009607 | ENSRBIP00000043669 | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | Agouti related neuropeptide. | 0.566 |
GHSR | GHRL | ENSRBIP00000009607 | ENSRBIP00000029484 | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | Ghrelin and obestatin prepropeptide. | 0.998 |
GHSR | LEP | ENSRBIP00000009607 | ENSRBIP00000041070 | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.430 |
LEP | AGRP | ENSRBIP00000041070 | ENSRBIP00000043669 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Agouti related neuropeptide. | 0.675 |
LEP | CARTPT | ENSRBIP00000041070 | ENSRBIP00000001289 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | CART prepropeptide. | 0.499 |
LEP | GHRL | ENSRBIP00000041070 | ENSRBIP00000029484 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Ghrelin and obestatin prepropeptide. | 0.892 |
LEP | GHSR | ENSRBIP00000041070 | ENSRBIP00000009607 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | 0.430 |