STRINGSTRING
AGRP AGRP NR1H3 NR1H3 YWHAH YWHAH PGRMC2 PGRMC2 ESR1 ESR1 ENSRBIP00000002079 ENSRBIP00000002079 SRC SRC LOC108534534 LOC108534534 THRB THRB PAQR7 PAQR7 SSTR3 SSTR3 SSTR2 SSTR2 PADI2 PADI2 RWDD1 RWDD1 NKX3-1 NKX3-1 ENSRBIP00000005518 ENSRBIP00000005518 NR3C1 NR3C1 PPARA PPARA GTF2H1 GTF2H1 ESRRB ESRRB CRHR2 CRHR2 RARG RARG CALCOCO1 CALCOCO1 ESRRG ESRRG GHSR GHSR ENSRBIP00000009767 ENSRBIP00000009767 EGLN2 EGLN2 LHCGR LHCGR NR5A2 NR5A2 RARB RARB ENSRBIP00000011876 ENSRBIP00000011876 OSTN OSTN RARA RARA IFT88 IFT88 ZMIZ1 ZMIZ1 TRERF1 TRERF1 SSTR1 SSTR1 TSHB TSHB SLC27A1 SLC27A1 APPL2 APPL2 DAXX DAXX POU4F2 POU4F2 PAQR8 PAQR8 CYP7B1 CYP7B1 DDX17 DDX17 GPER1 GPER1 MED1 MED1 METTL21C METTL21C RNF14 RNF14 KDM3A KDM3A NR2E1 NR2E1 ENSRBIP00000016878 ENSRBIP00000016878 GCGR GCGR DDX54 DDX54 NR1D2 NR1D2 TTC6 TTC6 NR3C2 NR3C2 PPARG-2 PPARG-2 LOC108522656 LOC108522656 ENSRBIP00000018684 ENSRBIP00000018684 RBFOX2 RBFOX2 ADIPOR1 ADIPOR1 TRH TRH ESRRA ESRRA LOC108531993 LOC108531993 NR5A1 NR5A1 SSTR5 SSTR5 LOC108525471 LOC108525471 ACSL1 ACSL1 ENSRBIP00000023025 ENSRBIP00000023025 REN REN RHOXF1 RHOXF1 NR4A3 NR4A3 PLPP1 PLPP1 HNF4A HNF4A YAP1 YAP1 PRLR PRLR ENSRBIP00000025371 ENSRBIP00000025371 PPARGC1B PPARGC1B ARID1A ARID1A NEDD4 NEDD4 ENSRBIP00000026419 ENSRBIP00000026419 ESR2 ESR2 FKBP4 FKBP4 PTPN11 PTPN11 CST11 CST11 TRIP4 TRIP4 THRA THRA ENSRBIP00000028880 ENSRBIP00000028880 GHRL GHRL UBR5 UBR5 DDX5 DDX5 LATS1 LATS1 PGR PGR RXRG RXRG RXRB RXRB CRHBP CRHBP LOC108533646 LOC108533646 ENSRBIP00000031796 ENSRBIP00000031796 ASIP ASIP ENSRBIP00000032719 ENSRBIP00000032719 TSHR TSHR NR2E3 NR2E3 UBE3A UBE3A RXFP2 RXFP2 ENSRBIP00000034253 ENSRBIP00000034253 NR1D1 NR1D1 CRHR1 CRHR1 SCGB2A1 SCGB2A1 PPARD PPARD ADIPOR2 ADIPOR2 PPARG PPARG APPL1 APPL1 WBP2 WBP2 RXRA RXRA BMP4 BMP4 LATS2 LATS2 ABHD2 ABHD2 NCOA4 NCOA4 TMF1 TMF1 ENSRBIP00000042683 ENSRBIP00000042683 ENSRBIP00000042840 ENSRBIP00000042840 BMP7 BMP7 PHB PHB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGRPAgouti related neuropeptide. (132 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (441 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (241 aa)
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (247 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
ENSRBIP00000002079Uncharacterized protein. (202 aa)
SRCTyrosine-protein kinase. (627 aa)
LOC108534534Prohibitin. (272 aa)
THRBThyroid hormone receptor beta. (476 aa)
PAQR7Progestin and adipoQ receptor family member 7. (346 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (417 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
PADI2Peptidyl arginine deiminase 2. (723 aa)
RWDD1RWD domain-containing protein. (234 aa)
NKX3-1NK3 homeobox 1. (230 aa)
ENSRBIP00000005518Prohibitin. (152 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
GTF2H1General transcription factor IIH subunit 1. (558 aa)
ESRRBEstrogen related receptor beta. (500 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
RARGUncharacterized protein. (456 aa)
CALCOCO1Calcium binding and coiled-coil domain 1. (691 aa)
ESRRGEstrogen related receptor gamma. (470 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ENSRBIP00000009767Uncharacterized protein. (546 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (405 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (645 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (541 aa)
RARBRetinoic acid receptor beta. (448 aa)
ENSRBIP00000011876Uncharacterized protein. (157 aa)
OSTNOsteocrin. (133 aa)
RARARetinoic acid receptor alpha. (478 aa)
IFT88Intraflagellar transport 88. (821 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1073 aa)
TRERF1Transcriptional regulating factor 1. (1199 aa)
SSTR1Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
SLC27A1Solute carrier family 27 member 1. (651 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa)
DAXXDeath domain associated protein. (740 aa)
POU4F2POU domain protein. (408 aa)
PAQR8Progestin and adipoQ receptor family member 8. (354 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (735 aa)
GPER1G protein-coupled estrogen receptor 1. (373 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
METTL21CMethyltransferase like 21C. (264 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
KDM3ALysine demethylase 3A. (1322 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
ENSRBIP00000016878Uncharacterized protein. (251 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (522 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (884 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (579 aa)
TTC6TPR_REGION domain-containing protein. (1871 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (867 aa)
PPARG-2Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa)
LOC108522656NR LBD domain-containing protein. (344 aa)
ENSRBIP00000018684Uncharacterized protein. (605 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (391 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
ESRRAUncharacterized protein. (400 aa)
LOC108531993RWD domain-containing protein. (211 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
SSTR5Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LOC108525471Uncharacterized protein. (356 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (721 aa)
ENSRBIP00000023025Uncharacterized protein. (387 aa)
RENRenin; Belongs to the peptidase A1 family. (433 aa)
RHOXF1Homeobox domain-containing protein. (185 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
YAP1Yes associated protein 1. (326 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
ENSRBIP00000025371RBR-type E3 ubiquitin transferase. (375 aa)
PPARGC1BPPARG coactivator 1 beta. (1024 aa)
ARID1AAT-rich interaction domain 1A. (2225 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1224 aa)
ENSRBIP00000026419Uncharacterized protein. (249 aa)
ESR2Estrogen receptor 2. (530 aa)
FKBP4Peptidylprolyl isomerase. (519 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
CST11Cystatin 11. (138 aa)
TRIP4Thyroid hormone receptor interactor 4. (510 aa)
THRAThyroid hormone receptor alpha. (524 aa)
ENSRBIP00000028880Uncharacterized protein. (375 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2727 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
LATS1Large tumor suppressor kinase 1. (1179 aa)
PGRProgesterone receptor. (935 aa)
RXRGRetinoid X receptor gamma. (463 aa)
RXRBRetinoid X receptor beta. (508 aa)
CRHBPCorticotropin releasing hormone binding protein. (275 aa)
LOC108533646Uncharacterized protein. (93 aa)
ENSRBIP00000031796HECT domain-containing protein. (669 aa)
ASIPAgouti signaling protein. (132 aa)
ENSRBIP00000032719SH2 domain-containing protein. (203 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
NR2E3Nuclear receptor subfamily 2 group E member 3. (425 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
RXFP2Relaxin family peptide receptor 2. (724 aa)
ENSRBIP00000034253BSD domain-containing protein. (465 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (444 aa)
SCGB2A1Secretoglobin family 2A member 1. (94 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
ADIPOR2Adiponectin receptor 2. (337 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (298 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (707 aa)
WBP2WW domain binding protein 2. (261 aa)
RXRARetinoid X receptor alpha. (492 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
LATS2Non-specific serine/threonine protein kinase. (1083 aa)
ABHD2Abhydrolase domain containing 2. (369 aa)
NCOA4Nuclear receptor coactivator 4. (650 aa)
TMF1TATA element modulatory factor 1. (1092 aa)
ENSRBIP00000042683Prohibitin. (189 aa)
ENSRBIP00000042840Prohibitin. (259 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
PHBProhibitin. (272 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: medium (52%) [HD]