20 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PKN2	Protein kinase N2. (556 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
	PRKD3	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (581 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
	MAPKAPK2	MAPK activated protein kinase 2. (392 aa)
	MAPKAPK5	MAPK activated protein kinase 5. (471 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	PKN1	Protein kinase N1. (965 aa)
	PRKD1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (434 aa)
	MKNK1	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
	PKN3	Protein kinase N3. (891 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (630 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (472 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
	MKNK2	MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
	PRKD2	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
	PRKCG	Protein kinase C. (726 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAPKAPK2	MAPKAPK3	ENSRBIP00000034363	ENSRBIP00000012098	MAPK activated protein kinase 2.	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	0.981
MAPKAPK3	MAPKAPK2	ENSRBIP00000012098	ENSRBIP00000034363	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2.	0.981
PKN1	PKN2	ENSRBIP00000027809	ENSRBIP00000004980	Protein kinase N1.	Protein kinase N2.	0.929
PKN1	PKN3	ENSRBIP00000027809	ENSRBIP00000019819	Protein kinase N1.	Protein kinase N3.	0.925
PKN2	PKN1	ENSRBIP00000004980	ENSRBIP00000027809	Protein kinase N2.	Protein kinase N1.	0.929
PKN2	PKN3	ENSRBIP00000004980	ENSRBIP00000019819	Protein kinase N2.	Protein kinase N3.	0.925
PKN2	PRKCA	ENSRBIP00000004980	ENSRBIP00000020301	Protein kinase N2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.574
PKN2	PRKCB	ENSRBIP00000004980	ENSRBIP00000021883	Protein kinase N2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.550
PKN2	PRKCG	ENSRBIP00000004980	ENSRBIP00000001216	Protein kinase N2.	Protein kinase C.	0.446
PKN2	PRKCI	ENSRBIP00000004980	ENSRBIP00000039024	Protein kinase N2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.494
PKN2	PRKCZ	ENSRBIP00000004980	ENSRBIP00000037173	Protein kinase N2.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.406
PKN3	PKN1	ENSRBIP00000019819	ENSRBIP00000027809	Protein kinase N3.	Protein kinase N1.	0.925
PKN3	PKN2	ENSRBIP00000019819	ENSRBIP00000004980	Protein kinase N3.	Protein kinase N2.	0.925
PKN3	PRKCG	ENSRBIP00000019819	ENSRBIP00000001216	Protein kinase N3.	Protein kinase C.	0.404
PRKCA	PKN2	ENSRBIP00000020301	ENSRBIP00000004980	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase N2.	0.574
PRKCA	PRKCD	ENSRBIP00000020301	ENSRBIP00000022764	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.947
PRKCA	PRKCE	ENSRBIP00000020301	ENSRBIP00000040835	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...]	0.942
PRKCA	PRKCG	ENSRBIP00000020301	ENSRBIP00000001216	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C.	0.969
PRKCA	PRKCI	ENSRBIP00000020301	ENSRBIP00000039024	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.451
PRKCA	PRKCQ	ENSRBIP00000020301	ENSRBIP00000031048	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.413