STRINGSTRING
BRCA2 BRCA2 BAK1 BAK1 CARD16 CARD16 BCL3 BCL3 ENSRBIP00000030285 ENSRBIP00000030285 TP53 TP53 MAP3K4 MAP3K4 ENSRBIP00000021949 ENSRBIP00000021949 ENSRBIP00000020407 ENSRBIP00000020407 HMGN1 HMGN1 WRN WRN POLH POLH C9orf116 C9orf116 IMPACT IMPACT DCUN1D3 DCUN1D3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRCA2Uncharacterized protein. (386 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
CARD16Caspase recruitment domain family member 16. (197 aa)
BCL3BCL3 transcription coactivator. (405 aa)
ENSRBIP00000030285DCN1-like protein. (296 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1565 aa)
ENSRBIP00000021949Uncharacterized protein. (110 aa)
ENSRBIP00000020407DCN1-like protein. (295 aa)
HMGN1Uncharacterized protein. (79 aa)
WRNWRN RecQ like helicase. (1394 aa)
POLHDNA polymerase eta. (697 aa)
C9orf116Chromosome 9 open reading frame 116. (136 aa)
IMPACTImpact RWD domain protein. (319 aa)
DCUN1D3DCN1-like protein. (304 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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