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| | PDK3 | Protein-serine/threonine kinase. (363 aa) |
| | PPARG-2 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa) |
| | FH | Fumarate hydratase. (451 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (519 aa) |
| | ETFBKMT | Electron transfer flavoprotein subunit beta lysine methyltransferase. (262 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (205 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | LOC108521987 | DUF3496 domain-containing protein. (153 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | IRS2 | Insulin receptor substrate 2. (904 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa) |
| | STAR | Steroidogenic acute regulatory protein. (294 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (115 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) |
| | APOA5 | Apolipoprotein A5. (366 aa) |
| | MTLN | Mitoregulin. (111 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (691 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | CYP7A1 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (405 aa) |
| | BMP6 | Bone morphogenetic protein 6. (440 aa) |
| | BCKDK | Protein-serine/threonine kinase. (412 aa) |
| | REST | RE1 silencing transcription factor. (1080 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa) |
| | PDK2 | Protein-serine/threonine kinase. (559 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (275 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (493 aa) |
| | CEACAM1 | Uncharacterized protein. (525 aa) |
| | AKT1 | AKT serine/threonine kinase 1. (486 aa) |
| | SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa) |
| | SIRT1 | Sirtuin 1. (731 aa) |
| | PANK2 | Pantothenate kinase 2. (574 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | LOC108522821 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (502 aa) |
| | SOX9 | SRY-box transcription factor 9. (305 aa) |
| | ENSRBIP00000009022 | CCDC144C domain-containing protein. (348 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (343 aa) |
| | DAB2 | DAB adaptor protein 2. (756 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (530 aa) |
| | ENSRBIP00000007851 | ANK_REP_REGION domain-containing protein. (97 aa) |
| | SCAP | SREBF chaperone. (1469 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (481 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (369 aa) |
| | LOC108526381 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (371 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa) |
| | ENSRBIP00000018276 | Uncharacterized protein. (194 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | TYSND1 | Trypsin domain containing 1. (566 aa) |
| | SLC22A13 | Solute carrier family 22 member 13. (551 aa) |
| | LOC108512216 | Uncharacterized protein. (377 aa) |
| | LOC108532992 | Aldo-keto reductase family 1 member C1. (303 aa) |
| | ENSRBIP00000021372 | Lyase_1 domain-containing protein. (175 aa) |
| | CLN3 | Battenin. (438 aa) |
| | APOC2 | Apolipoprotein C2. (101 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (461 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | PPTC7 | Protein phosphatase; Belongs to the PP2C family. (304 aa) |
| | SLC7A7 | Solute carrier family 7 member 7. (511 aa) |
| | PARK7 | Parkinsonism associated deglycase. (191 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) |
| | ERFE | Erythroferrone. (348 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (749 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (283 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | ERLIN2 | ER lipid raft associated 2. (380 aa) |
| | BMP5 | TGF_BETA_2 domain-containing protein. (154 aa) |
| | ENSRBIP00000027656 | START domain-containing protein. (252 aa) |
| | ENSRBIP00000028026 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (139 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2488 aa) |
| | DGKQ | Diacylglycerol kinase. (849 aa) |
| | FABP1 | Fatty acid binding protein 1. (127 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2163 aa) |
| | ENSRBIP00000030628 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (118 aa) |
| | PDK1 | Protein-serine/threonine kinase. (436 aa) |
| | ANKRD26 | Ankyrin repeat domain 26. (1667 aa) |
| | ATCAY | ATCAY kinesin light chain interacting caytaxin. (343 aa) |
| | GIP | Gastric inhibitory polypeptide. (151 aa) |
| | PLA2G3 | Phospholipase A2 group III. (508 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (385 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1309 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (666 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2441 aa) |
| | PDK4 | Protein-serine/threonine kinase. (411 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2458 aa) |
| | AVP | Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (298 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | LOC108532991 | Aldo_ket_red domain-containing protein. (323 aa) |
| | ENSRBIP00000038661 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (104 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (501 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa) |
| | ADM | Adrenomedullin. (185 aa) |
| | LOC108540985 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (734 aa) |
| | BMP2 | Bone morphogenetic protein 2. (321 aa) |
| | FABP5-2 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | MLXIPL | MLX interacting protein like. (798 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (357 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (462 aa) |
| | CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (762 aa) |
| | ENSRBIP00000001673 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa) |
| | MID1IP1 | MID1 interacting protein 1. (183 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (350 aa) |
| | FABP3 | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | CLCN2 | Chloride channel protein. (898 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa) |
| | ENSRBIP00000000642 | FABP domain-containing protein. (121 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (441 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1047 aa) |
