(36 nodes) Regulation of myotube differentiation network (Rhinopithecus bieti)

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second shell of interactors

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Predicted Interactions

gene neighborhood

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Your Input:
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	PIEZO1	Piezo-type mechanosensitive ion channel component. (2423 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (961 aa)
	RBM38	RNA binding motif protein 38. (234 aa)
	SHOX2	Short stature homeobox 2. (355 aa)
	RBM24	RNA binding motif protein 24. (255 aa)
	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator. (312 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	TBX1	T-box transcription factor 1. (371 aa)
	MMP14	Matrix metallopeptidase 14. (582 aa)
	SMYD1	SET and MYND domain containing 1. (490 aa)
	MYOG	Myogenin. (249 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1178 aa)
	MYOCD	Myocardin. (832 aa)
	NIBAN2	Niban apoptosis regulator 2. (746 aa)
	NOTCH1	Notch receptor 1. (2438 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (189 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	CCN3	Cellular communication network factor 3. (357 aa)
	MYF6	Myogenic factor 6. (242 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
	DMPK	DM1 protein kinase. (630 aa)
	TRIM72	Tripartite motif containing 72. (479 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1123 aa)
	BHLHE41	Basic helix-loop-helix family member e41. (460 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	FBXO22	F-box protein 22. (404 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	PLPP7	Phospholipid phosphatase 7 (inactive). (271 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (937 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2527 aa)
	LMOD3	Leiomodin 3. (553 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	NKX2-5	NK2 homeobox 5. (325 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MYF6	ENSRBIP00000005898	ENSRBIP00000020062	Actinin alpha 3 (gene/pseudogene).	Myogenic factor 6.	0.456
BCL2	MAPK14	ENSRBIP00000010712	ENSRBIP00000027919	BCL2 apoptosis regulator.	Mitogen-activated protein kinase.	0.419
BCL2	MTOR	ENSRBIP00000010712	ENSRBIP00000004660	BCL2 apoptosis regulator.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.420
BCL2	XBP1	ENSRBIP00000010712	ENSRBIP00000021062	BCL2 apoptosis regulator.	BZIP domain-containing protein.	0.406
CAV3	TRIM72	ENSRBIP00000001580	ENSRBIP00000019002	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tripartite motif containing 72.	0.824
CCN3	NOTCH1	ENSRBIP00000020466	ENSRBIP00000022251	Cellular communication network factor 3.	Notch receptor 1.	0.435
HDAC4	HDAC5	ENSRBIP00000021353	ENSRBIP00000018063	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.936
HDAC4	MYOD1	ENSRBIP00000021353	ENSRBIP00000014936	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.495
HDAC4	MYOG	ENSRBIP00000021353	ENSRBIP00000032471	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myogenin.	0.433
HDAC5	HDAC4	ENSRBIP00000018063	ENSRBIP00000021353	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.936
MAML1	NOTCH1	ENSRBIP00000043234	ENSRBIP00000022251	Mastermind like transcriptional coactivator 1.	Notch receptor 1.	0.990
MAPK14	BCL2	ENSRBIP00000027919	ENSRBIP00000010712	Mitogen-activated protein kinase.	BCL2 apoptosis regulator.	0.419
MAPK14	MTOR	ENSRBIP00000027919	ENSRBIP00000004660	Mitogen-activated protein kinase.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.434
MAPK14	MYF6	ENSRBIP00000027919	ENSRBIP00000020062	Mitogen-activated protein kinase.	Myogenic factor 6.	0.410
MAPK14	MYOD1	ENSRBIP00000027919	ENSRBIP00000014936	Mitogen-activated protein kinase.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.573
MAPK14	MYOG	ENSRBIP00000027919	ENSRBIP00000032471	Mitogen-activated protein kinase.	Myogenin.	0.479
MMP14	MYOG	ENSRBIP00000034948	ENSRBIP00000032471	Matrix metallopeptidase 14.	Myogenin.	0.464
MTOR	BCL2	ENSRBIP00000004660	ENSRBIP00000010712	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	BCL2 apoptosis regulator.	0.420
MTOR	MAPK14	ENSRBIP00000004660	ENSRBIP00000027919	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Mitogen-activated protein kinase.	0.434
MTOR	NOTCH1	ENSRBIP00000004660	ENSRBIP00000022251	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Notch receptor 1.	0.423