STRINGSTRING
ENSRBIP00000017297 ENSRBIP00000017297 JUP JUP CTNNB1 CTNNB1 TJP1 TJP1 NEDD4 NEDD4 TMEM114 TMEM114 CRB2 CRB2 MTCL1 MTCL1 CLDN3 CLDN3 MPDZ MPDZ CLDN7 CLDN7 CXADR CXADR PALM PALM FZD6 FZD6 OCLN OCLN CLDN4 CLDN4 ENSRBIP00000009563 ENSRBIP00000009563 CLDN5 CLDN5 CLDN8 CLDN8 KRT19 KRT19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRBIP00000017297IF rod domain-containing protein; Belongs to the intermediate filament family. (387 aa)
JUPJunction plakoglobin. (709 aa)
CTNNB1Catenin beta 1. (781 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1737 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1224 aa)
TMEM114Transmembrane protein 114. (223 aa)
CRB2Crumbs cell polarity complex component 2. (1108 aa)
MTCL1Microtubule crosslinking factor 1. (1750 aa)
CLDN3Claudin 3. (211 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2049 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
PALMParalemmin. (378 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
ENSRBIP00000009563IF rod domain-containing protein; Belongs to the intermediate filament family. (372 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
KRT19IF rod domain-containing protein; Belongs to the intermediate filament family. (386 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (18%) [HD]