STRINGSTRING
MECP2 MECP2 BRCA2 BRCA2 ATXN7 ATXN7 PHF20 PHF20 SF3B5 SF3B5 TAF12 TAF12 MSL2 MSL2 OGT OGT JADE2 JADE2 IRF4 IRF4 ACTB ACTB LOC108519624 LOC108519624 PER1 PER1 LOC108525824 LOC108525824 ZMPSTE24 ZMPSTE24 MAP3K7 MAP3K7 LDB1 LDB1 JADE1 JADE1 GTF3C4 GTF3C4 KAT2A KAT2A ATXN7L2 ATXN7L2 KAT2B KAT2B VPS72 VPS72 YEATS2 YEATS2 MCRS1 MCRS1 LEF1 LEF1 ATXN7L3 ATXN7L3 TADA2A TADA2A ING4 ING4 ENSRBIP00000011112 ENSRBIP00000011112 BRPF3 BRPF3 SUPT3H SUPT3H PCGF2 PCGF2 ACTL6B ACTL6B WDR5 WDR5 NCOA3 NCOA3 EPC2 EPC2 MCM3AP MCM3AP HNF1A HNF1A NAA40 NAA40 BRPF1 BRPF1 KANSL2 KANSL2 KAT7 KAT7 MYOD1 MYOD1 TADA3 TADA3 ATXN7L1 ATXN7L1 MLLT1 MLLT1 EPC1 EPC1 MBTD1 MBTD1 CHD5 CHD5 MSL1 MSL1 TEX30 TEX30 LOC108526377 LOC108526377 KANSL1 KANSL1 MBD3 MBD3 HAT1 HAT1 PAX6 PAX6 RUVBL1 RUVBL1 MBIP MBIP FOXP3 FOXP3 NAA50 NAA50 TAF5L TAF5L CRTC2 CRTC2 MORF4L1 MORF4L1 NAA60 NAA60 KAT6A KAT6A TAF6 TAF6 MRGBP MRGBP RUVBL2 RUVBL2 NCOA1 NCOA1 ENSRBIP00000022866 ENSRBIP00000022866 KAT8 KAT8 BRD1 BRD1 SRCAP SRCAP DR1 DR1 ENSRBIP00000024049 ENSRBIP00000024049 ENSRBIP00000024059 ENSRBIP00000024059 SPHK2 SPHK2 ACTL6A ACTL6A APBB1 APBB1 TAF6L TAF6L TRIM16 TRIM16 KAT5 KAT5 ENSRBIP00000029472 ENSRBIP00000029472 MED24 MED24 PBXIP1 PBXIP1 HCFC1 HCFC1 CREBBP CREBBP TAF4 TAF4 ING3 ING3 LOC108514681 LOC108514681 ENSRBIP00000031407 ENSRBIP00000031407 BEND3 BEND3 JADE3 JADE3 KANSL3 KANSL3 SUPT7L SUPT7L TAF1 TAF1 TAF2 TAF2 ING5 ING5 DMAP1 DMAP1 EP300 EP300 BRD8 BRD8 SGF29 SGF29 GTF2B GTF2B ENSRBIP00000034744 ENSRBIP00000034744 ENSRBIP00000034867 ENSRBIP00000034867 CLOCK CLOCK ENSRBIP00000035213 ENSRBIP00000035213 TAF10 TAF10 ATF2 ATF2 ENY2 ENY2 YEATS4 YEATS4 ZZZ3 ZZZ3 POLE3 POLE3 MEAF6 MEAF6 EOMES EOMES TAF5 TAF5 CPA4 CPA4 TRRAP TRRAP PHF20L1 PHF20L1 MLLT3 MLLT3 EP400 EP400 KAT14 KAT14 ENSRBIP00000041672 ENSRBIP00000041672 TADA1 TADA1 KAT6B KAT6B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
BRCA2Uncharacterized protein. (386 aa)
ATXN7SCA7 domain-containing protein. (879 aa)
PHF20PHD finger protein 20. (1011 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
MSL2MSL complex subunit 2. (577 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (886 aa)
JADE2Jade family PHD finger 2. (834 aa)
IRF4Interferon regulatory factor 4. (450 aa)
ACTBActin beta. (379 aa)
LOC108519624MRG domain-containing protein. (208 aa)
PER1Period circadian regulator 1. (1227 aa)
LOC108525824Uncharacterized protein. (121 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (441 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LDB1LIM domain binding 1. (411 aa)
JADE1Jade family PHD finger 1. (843 aa)
GTF3C4General transcription factor IIIC subunit 4. (822 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
ATXN7L2Ataxin 7 like 2. (711 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
VPS72Vacuolar protein sorting 72 homolog. (364 aa)
YEATS2YEATS domain containing 2. (1261 aa)
MCRS1Microspherule protein 1. (475 aa)
LEF1Lymphoid enhancer binding factor 1. (398 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
TADA2ATranscriptional adapter. (382 aa)
ING4Inhibitor of growth protein. (252 aa)
ENSRBIP00000011112Uncharacterized protein. (159 aa)
BRPF3Bromodomain and PHD finger containing 3. (1229 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (328 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
ACTL6BActin like 6B; Belongs to the actin family. (440 aa)
WDR5WD repeat domain 5. (334 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
EPC2Enhancer of polycomb homolog. (702 aa)
MCM3APMinichromosome maintenance complex component 3 associated protein. (1925 aa)
HNF1AHNF1 homeobox A. (662 aa)
NAA40N(alpha)-acetyltransferase 40, NatD catalytic subunit. (274 aa)
BRPF1Uncharacterized protein. (1253 aa)
KANSL2KAT8 regulatory NSL complex subunit 2. (676 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (606 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
TADA3Transcriptional adaptor 3. (432 aa)
ATXN7L1Ataxin 7 like 1. (859 aa)
MLLT1MLLT1 super elongation complex subunit. (523 aa)
EPC1Enhancer of polycomb homolog. (836 aa)
MBTD1Mbt domain containing 1. (722 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1978 aa)
MSL1MSL complex subunit 1. (613 aa)
TEX30Testis expressed 30. (227 aa)
LOC108526377MRG domain-containing protein. (291 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (782 aa)
MBD3Methyl-CpG binding domain protein 3. (259 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (486 aa)
PAX6Paired box 6. (462 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
MBIPMAP3K12 binding inhibitory protein 1. (320 aa)
FOXP3Forkhead box P3. (456 aa)
NAA50N(alpha)-acetyltransferase 50, NatE catalytic subunit. (168 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
CRTC2CREB regulated transcription coactivator 2. (699 aa)
MORF4L1Mortality factor 4 like 1. (361 aa)
NAA60N(alpha)-acetyltransferase 60, NatF catalytic subunit. (242 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1703 aa)
TAF6TATA-box binding protein associated factor 6. (737 aa)
MRGBPMRG domain binding protein. (179 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
NCOA1Nuclear receptor coactivator. (1433 aa)
ENSRBIP00000022866MRG domain-containing protein. (317 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (469 aa)
BRD1Bromodomain containing 1. (1094 aa)
SRCAPUncharacterized protein. (3230 aa)
DR1Down-regulator of transcription 1. (176 aa)
ENSRBIP00000024049EP400_N domain-containing protein. (391 aa)
ENSRBIP00000024059Chromo domain-containing protein. (457 aa)
SPHK2Sphingosine kinase 2. (658 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (746 aa)
TAF6LTATA-box binding protein associated factor 6 like. (622 aa)
TRIM16B30.2/SPRY domain-containing protein. (348 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
ENSRBIP00000029472MRG domain-containing protein. (514 aa)
MED24Mediator complex subunit 24. (1028 aa)
PBXIP1PBX homeobox interacting protein 1. (737 aa)
HCFC1Host cell factor C1. (2060 aa)
CREBBPCREB binding protein. (2422 aa)
TAF4TATA-box binding protein associated factor 4. (1026 aa)
ING3Inhibitor of growth protein. (418 aa)
LOC108514681Uncharacterized protein. (252 aa)
ENSRBIP00000031407MRG domain-containing protein. (160 aa)
BEND3BEN domain containing 3. (828 aa)
JADE3Jade family PHD finger 3. (823 aa)
KANSL3KAT8 regulatory NSL complex subunit 3. (880 aa)
SUPT7LSPT7 like, STAGA complex gamma subunit. (412 aa)
TAF1TATA-box binding protein associated factor 1. (1713 aa)
TAF2TATA-box binding protein associated factor 2. (863 aa)
ING5Inhibitor of growth family member 5. (254 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
EP300E1A binding protein p300. (2296 aa)
BRD8Bromodomain containing 8. (1236 aa)
SGF29SAGA complex associated factor 29. (304 aa)
GTF2BGeneral transcription factor IIB. (222 aa)
ENSRBIP00000034744Uncharacterized protein. (127 aa)
ENSRBIP00000034867MRG domain-containing protein. (217 aa)
CLOCKClock circadian regulator. (847 aa)
ENSRBIP00000035213Uncharacterized protein; Belongs to the actin family. (362 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (229 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (429 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
YEATS4YEATS domain containing 4. (224 aa)
ZZZ3Uncharacterized protein. (905 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
MEAF6Uncharacterized protein. (171 aa)
EOMESEomesodermin. (410 aa)
TAF5TATA-box binding protein associated factor 5. (610 aa)
CPA4Carboxypeptidase A4. (421 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3824 aa)
PHF20L1PHD finger protein 20 like 1. (1017 aa)
MLLT3MLLT3 super elongation complex subunit. (369 aa)
EP400E1A binding protein p400. (3059 aa)
KAT14Lysine acetyltransferase 14. (781 aa)
ENSRBIP00000041672Uncharacterized protein. (174 aa)
TADA1Transcriptional adaptor 1. (334 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2079 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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